Hipotiroidia subclinică – aspecte clinice şi de diagnostic

Abstract

Subclinical hypothyroidism is characterized by increased serum TSH concentrations associated with normal levels of circulating total and free thyroxine (fT4). The clinical significance of subclinical hypothyroidism is much debated. Subclinical hypothyroidism can have repercussions on the cardiovascular system and other organs and systems. The purpose of this study is to evaluate the clinical and therapeutical significance of the subclinical hypothyroidism.

Hipotiroidia subclinică reprezintă majorarea TSH-lui plasmatic asociată cu nivel plasmatic normal a T4 total şi fT4. Semnificaţia clinică a acestei patologii rămîne subiect controversat. Hipotiroidia subclinică se asociază cu risc înalt cardio-vascular şi de afectare a altor organe şi sisteme. Scopul acestei lucrări este evaluarea semnificaţiei clinice şi terapeutice a hipotiroidiei subclinice.