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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3949
Title: Role of mast cells in tumor progression
Other Titles: Rolul mastocidelor în progresia tumorală
Authors: Stratan, Nadejda
Cazac, Victor
Issue Date: 2010
Publisher: CEP Medicina
Citation: STRATAN, Nadejda, CAZAC Victor. Role of mast cells in tumor progression. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 1: Probleme medico-biologice si farmaceutice, pp. 134-143.
Abstract: The aim of this article is to show the key points regarding the crucial role of mast cells in supporting and promoting tumor progression. The article reveals important facts about both the immunosuppressive function of mast cells, that greatly enhances the tumor progression, as well as the changes in intercellular junctions induced by mast cell activity. Additionally, the article focuses on blood and lymphatic vessels growth provided by mast cell activity, an essential prerequisite necessary for tumor growth. Rolul mastocidelor în progresia tumorală Scopul acestui articol este de a prezenta momentele cheie privitor la rolul crucial al mastocitelor în promovarea progresiei tumorale. Articolul aduce informaţii importante atât despre funcţia imunosupresivă a mastocitelor, care considerabil duce la accelerarea progresiei tumorale, cât şi despre modificările joncţiunilor intercelulare induse de activitatea mastocitelor. Deasemenea, articolul descrie angiogeneza şi limfangiogeneza promovată de activitatea mastocitelor, o premisă necesară pentru creşterea tumorală.
URI: http://repository.usmf.md/handle/20.500.12710/3949
Appears in Collections:Morfologie normală și patologică

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