Conceptul polietiologic al pancreatitei cronice

Abstract

The study included 265 patients who had been evaluated the pathogenic spectrum of different clinical forms of chronic pancreatitis (CP) and 25 patients with CP and a family history of CP . The results proved CP to be a disease of diverse ethiology, one being the alcohol consumption. In CP patients with a family history when the onset occurs at a young age, the recurrent form with dolor syndrome prevails, this developing into exo- and/or endocrine insufficiency. A deeper assessment of pathogenic spectrum of CP, including the genetic factors, would allow the prevention, early diagnosis, proper treatment and reduction of CP risks development.

Studiul a inclus 265 pacienţi, diagnosticaţi cu diferite forme clinice de pancreatită cronică (PC) şi 25 pacienţi cu PC cu anamneză familială. Rezultatele obţinute au demonstrat că PC este o maladie polietiologică, rolul principal revenindu-i consumului de alcool. La pacienţii cu PC cu anamneză familială debutul are loc la o vărstă tănără, predomină forma recidivantă cu sindrom dolor, cu progresarea spre insuficienţă exo- şi/sau endocrină. Evaluarea mai profundă a spectrului etiopatogenic al PC ar permite prevenirea, diagnosticarea precoce, elaborarea unui tratament corect şi reducerea riscurilor acestei patologii.