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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4660
Title: Inhibina B marker în răspunsul ovarian
Other Titles: Inhibin B a marker for ovarian response
Authors: Cauş, Natalia
Issue Date: 2011
Publisher: CEP Medicina
Citation: CAUŞ, Natalia. Inhibina B marker în răspunsul ovarian. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 5: Probleme actuale ale sănătăţii mamei si copilului, pp.136-139.
Abstract: Inhibin B is a heterodimetric glycoprotein released by the granulosa cells of the follicle. The low concentration was predictive for a poor ovarian response and decreased the success 137 during IVF cycles. Inhibin B concentrations in follicular fluid increase during the menstrual cycle correlated to the ovarian follicle development, proceeding with a mean of 19.2ng/ml in 5mm follicles, 409ng/ml in 14mm follicles, but with decline in 18 mm follicles to 275ng/ml. Keyword inhibin B, infertility, ovarian reserve, IVF Inhibinele sunt hormoni polipeptidici heterodimerici care suprima selectiv secretia hipofizara de hormon foliculo-stimulant (FSH) si exercita actiuni paracrine locale asupra gonadelor. Formele finale ale moleculelor de inhibine au o greutate moleculara de aproximativ 32-36 kD si sunt alcatuite din 2 lanturi distincte α si β unite prin punti disulfidice. Numeroase studii atestă utilitatea determinării de inhibina B ca marker endocrin pentru monitorizarea funcţiei gonadale la ambele sexe. Cuvinte chee: inhibina B , infertilitate, rezerva ovariana, FIV
URI: http://repository.usmf.md/handle/20.500.12710/4660
Appears in Collections:Obstetrică și ginecologie

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