The Moldovan Medical Journal: Recent submissions

  • Clinical and laboratory biomarkers to predict haemorrhagic transformation of ischemic stroke: first data of a prospective study 
    Costru-Tașnic, Elena; Gavriliuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Haemorrhagic transformation of ischemic stroke represents the bleeding in the infarcted areas of the brain after the cerebrovascular accident. The aim of the study was to analyse the clinical parameters and ...
  • Medication overuse in patients with headache during the COVID-19 pandemic 
    Cebotari, Ecaterina; Grosu, Oxana; Odobescu, Stela; Rotaru, Lilia; Corcea, Galina; Moldovanu, Ion (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Medication overuse in patients with headache is the most important risk factor for secondary headache. According to ICHD criteria, the use of analgesics or triptans for more than 10 days / month and combined ...
  • Physician`s knowledge, attitudes and practices regarding the management of major cognitive disorders in the Republic of Moldova 
    Caliga, Ioana; Grosu, Oxana; Odobescu, Stela; Rotaru, Lilia; Corcea, Galina; Moldovanu, Ion (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The number of people living with dementia worldwide is increasing exponentially. It is estimated to be doubled by 2030 and tripled by 2050. The management of cognitive disorders is a developing field in the ...
  • Subarachnoid hemorrhage associated with COVID-19 infection: case series report 
    Zolotco, Galina; Grosu, Oxana; Rotaru, Lilia; Corcea, Galina; Andronachi, Victor; Zapuhlih, Grigore (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Subarachnoid hemorrhage is a sudden bleeding in the subarachnoid space, representing 5-10% of all strokes. Several reports of Covid-19 infection and subarachnoid hemorrhage have been published. The objective ...
  • Brain structural integrity and connectivity in Multiple Sclerosis patients with epilepsy 
    Ciolac, Dumitru (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Seizures and epilepsy in multiple sclerosis (MS) have been related to grey matter (GM) pathology. However, the link between epilepsy occurrence and GM alterations in MS is still poorly understood. Hence, we ...
  • Epidemiological data on Myasthenia gravis related to SARS-COV-2 infections in the Republic of Moldova 
    Lisnic, Vitalie; Bubuioc, Ana-Maria; Alboini, Paulo Emilio; Leone, Maurizio Angelo (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The aim of this study is to provide an estimated incidence of Myasthenia Gravis (MG) and to describe the pattern of the disease in the Republic of Moldova before and during the COVID-19 pandemic. Material and ...
  • The impact of the pandemic on the in – hospital stroke quality indicators based on the RES-Q Register 
    Serebreanschi, Elena; Manole, Elena; Odainic, Olesea; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Coronavirus pandemic (COVID-19) has influenced not only global morbidity statistics, but also healthcare ones in relation to other diseases, including stroke. The aim of the study was to analyse the in-hospital ...
  • Four years’ experience of participation of the Republic of Moldova in the RES-Q Registry 
    Manole, Elena; Ciobanu, Natalia; Crivorucica, Igor; Odainic, Olesea; Lisnic, Vitalie; Zota, Eremei; Plotnicu, Sorin; Turcanu, Ghenadie; Harco, Ala; Cravcenco, Natalia; Cretu, Natalia; Todirean, Rodica; Dolghier, Valentina; Barbaros, Valentina; Crijanovschi, Svetlana; Eleniuc, Diana; Salcutanu, Veaceslav; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The Republic of Moldova is a member of the Registry of Stroke Care Quality (RES-Q) project, initiated by the European Stroke Organization in 2016. The aim of this study was to analyze the in-hospital stroke ...
  • Prevalence and clinical peculiarities of Multiple Sclerosis in the Republic of Moldova 
    Belenciuc, Anna; Odainic, Olesea; Lisnic, Vitalie; Leone, Maurizio Angelo (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, neurodegenerative disease of the central nervous system and the most common disabling neurological disease in young adults. The disease natural ...
  • Anxiety and sympathetic skin responses in patients with masticatory muscle pain 
    Fala, Valeriu; Lacusta, Victor; Bordeniuc, Gheorghe (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: An important clinical aspect of masticatory muscle pain is its association with autonomic disorders and various mental states. Sympathetic skin response is a non-invasive approach for assessing sympathetic ...
  • Objective assesment of sympathetic electrodermal activity in patients with masticatory muscle pain 
    Bordeniuc, Gheorghe; Lacusta, Victor; Fala, Valeriu (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Masticatory muscle pain is associated with autonomic disorders of different intensity; their identification leads to a more accurate diagnosis and a differentiated treatment. Currently, various scales and ...
  • Assessment of risk factors in post-stroke cognitive impairment 
    Gavriluta, Diana; Gasnas, Alexandru; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Cognitive impairment is a frequent symptom in post-stroke patients, with a prevalence range of 20% to 80%. Our study’s aim was to analyze the previously reported risk factors in order to highlight predictors ...
  • Anxiety in epilepsy. Gender differences 
    Doten, Natalia (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The aim of the study was to assess the prevalence of anxiety symptoms in women and men with epilepsy, and to evaluate their relationships with psychological variables: duration of the epilepsy disease, education, ...
  • Evolution of status epilepticus in children 
    Calcii, Cornelia; Sprincean, Mariana; Lupușor, Nadejda; Griu, Corina; Cuznet, Ludmila; Racovita, Stela; Feghiu, Ludmila; Hadjiu, Svetlana (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Status epilepticus is defined as a neurologic emergency in which there is at least 5 minutes of continuous seizure activity or recurrent seizures with a return to baseline between seizures. The aim of this ...
  • Imaging aspects in Spastic Cerebral Palsy in children 
    Cuznet, Ludmila; Hadjiu, Svetlana; Calcii, Cornelia; Griu, Corina; Racovita, Stela; Lupușor, Nadejda; Feghiu, Ludmila; Sprincean, Mariana; Revenco, Ninel (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Magnetic resonance imaging (MRI) is commonly used in the investigation of children with cerebral palsy (CP). This investigation suggests hope in future therapeutic interventions of children with CP. The aim ...
  • Clinical features and outcome in patients with Guillain-Barré syndrome 
    Lentitchii, Alina; Haider, Zeyba; Melnic, Adrian; Sangheli, Marina; Plesca, Svetlana; Simon, Victoria (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Guillain-Barré syndrome (GBS) is a heterogeneous group of autoimmune polyradiculopathies, in which disease biomarkers, and outcome predictors are under continuous research. Material and methods: Thirty-three ...
  • SARS-Cov-2 associated periferal neuropathy and congenital myopathy: case report 
    Rusu, Irina; Lisnic, Vitalie; Railean, Gheorghe (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Association of congenital myopathy with COVID-19 – associated peripheral neuropathy is not reported. We aim to present such a case. Material and methods: Clinical case of a 14-year-old male with history of ...
  • Results of the cohort study of cognitive impairment associated with Parkinson's disease 
    Rotaru, Lilia (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Cognitive impairment (CI) is frequent in Parkinson’s Disease (PD), having particular features. Material and methods: Sixty-five consecutive PD patients, (mean age 64.87 ± 7.69 y.o.; disease duration 50.21 ± ...
  • Role of nutritional and lifestyle factors on the Amyotrophic Lateral Sclerosis progression. Results from a multicenter cross-sectional study 
    Cucovici, Aliona; Ivashynka, Andrei; Fontana, Andrea; Lisnic, Vitalie; Leone, Maurizio A. (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Amyotrophic Lateral Sclerosis is a devastating, untreatable motor neuron disease with unknown causes, but nutritional and lifestyle factors may play a role. To check this hypothesis, we conducted a multicentre ...
  • Treatment of acute ischemic stroke by systemic thrombolysis combined with endovascular thrombectomy: case report 
    Condrea, Alexandra; Zota, Eremei; Crivorucica, Igor; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: A small number of acute ischemic stroke (AIS) patients meets eligibility criteria for systemic thrombolysis (ST) with recombinant tissue plasminogen activator, but its efficacy for large vessel occlusion is ...

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