Abstract:
Background: Preoperative embolization of intracranial tumors is used for more than four decades to minimize intraoperative
bleeding and facilitate surgical removal. The goal of embolization is to occlude intratumoral vessels and the large feeding
arteries. Preoperative embolization is recommended for large menigiomas (>3–4 cm in diameter) with pure or predominant
external carotid artery supply, tumors in eloquent areas and hypervascular tumors. Debate remains on several aspects of
preoperative embolization of meningiomas including selection of embolic agent and injected volume as well as optimal
timing of embolization before the open surgery.
Content: The presentation provides a brief overview of embolization agents and techniques. We also present two patients with
large intracranial meningiomas (located on the sphenoid wing and the parasagittal region) who underwent microsurgery
during the same session aft er endovascular treatment. In both cases the tumor was embolized with microparticles, aft er
which we resected the tumor in our hybrid operating room. Complete tumor resection (Simpson Grade II) was achieved in
both cases. The estimated blood loss was about 500 ml for each intervention. Postoperative histopathological exam revealed
embolization particles in tumor vessels and small foci of necrosis.
Conclusions: The implementation of preoperative embolization can further improve the treatment strategy of intracranial
tumors in our country. We hope that the combination of microsurgical and endovascular techniques would lead to
improvement in overall clinical outcomes and further reduce the mortality and morbidity of neurooncological patients.
Description:
Department of Neurosurgery, Republican Clinical Hospital, Nicolae Testemitsanu State University of Medicine and Pharmacy, CSD Moldova Pathology Laboratory, Chisinau, the Republic of Moldova, The IVth Congress of Radiology and Medical Imaging of the Republic of Moldova with international participation, Chisinau, May 31 – June 2, 2018