Abstract:
Background: COVID-19 is a part of the betacoronaviridae group, sabercoviridae subgroup. At the moment we are confronting a pandemy, which has
a completely new pathologic pattern for the whole world. Considering the highly contagious characteristics of the virus, which is the cause of death for
many people, and also the fact that many people continue to be infected with this virus there is a stringing necesity of combating this pandemy. Because
of that we need the knowledge that regards the physiopathologic mechanisms, particularities of the host-invader interactions, relevance of asymptomatic
forms, explanations of the evolving divergencies, posibility of recurrent infections, clinical signs, comorbidities that harshen this pathology, pharmacologic
agents that are effective to fight the infection and immune mechanisms of defense in the organism. A great importance is given for the identification of
the intial criteria needed for a prognostic, to prevent the critical forms of pathology and to set the parameters for the severity indicators.
Conclusions: The research in the field of SARS-CoV-2 requires the gathering of the databases that are related to the investigated persons, to establish the
clinico-evolutive differences for the COVID-19 patients according to many factors that could influence the course of the disease. An important difference
is the identification of early signs and prevention of the critical disease forms, by extending the laboratory investigations, establishing the parameters for
severity indicators through determining the degree of the immune response.
Description:
Department of Infectious Diseases, Department of Infectious Diseases, Tropical and Medical Parasitology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova