Abstract:
Introduction: A solution to resolve
gastroesophageal reflux is to increase
the tonus of the inferior esophageal
sphincter through electrostimulation.
The type of electrostimulation and the
optimal parameters remains a dispute in the medical field.
Purpose: To obtain clinical data
from laboratory animals regarding
the effects of different types of
electrostimulation of IES, elaboration and testing the prototype of
implantable and rechargeable microstimulator through cordless energy
transfer.
Material and methods: In
Department of surgery Nr.4 over the
course of 4 years (2015-2018), there
has been performed a randomized,
prospective clinical experimental
study of inferior esophageal sphincter
electrostimulation.
Results: In the first stage the study aimed to
determine the optimal parameters of IES electrostimulation through the clinical and paraclinical
analysis of 15 patients. In the second stage there has
been created an experimental device that consisted of
an implantable microstimulator in which cordless
energy transfer was used, following the testing on
laboratory animals at Center of Experimental Surgery
„Pius Brânzeu”, Timișoara, Romania.The value of
resting pressure of IES and the integrate resting
pressure (IRP) were significantly different in the
before and after stimulation.
Conclusions: In the first stage the study aimed to
determine the optimal parameters of IES electrostimulation through the clinical and paraclinical
analysis of 15 patients. In the second stage there has
been created an experimental device that consisted of
an implantable microstimulator in which cordless
energy transfer was used, following the testing on
laboratory animals at Center of Experimental Surgery
„Pius Brânzeu”, Timișoara, Romania.The value of
resting pressure of IES and the integrate resting
pressure (IRP) were significantly different in the before
and after stimulation.
Description:
State Medical Pharmaceutical University ”Nicolae Testemițanu”, State Technical University of Republic Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltare
