• Lung transplantation in the management of cystic fibrosis 

  Rotaru, Ludmila; Rotaru, Tudor (CEP Medicina, 2026)

  Introduction. Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the CFTR gene, affecting multiple organs, particularly the lungs, and leading to progressive respiratory failure. Despite ...
• Fecal microbiota transplantation in metabolic syndrome 

  Potînga, Irina; Protopop, Svetlana (CEP Medicina, 2026)

  Introduction. Metabolic syndrome (MetS) is a multifactorial disease, and the gut microbiota plays an important role in its pathogenesis. Moreover, recent studies suggest associations between gut dysbiosis and components ...
• Pancreatic islet cell autotransplantation as a therapeutic option in chronic pancreatitis complicated by pancreatic pseudocyst 

  Pîrțac, Mihail; Berliba, Sergiu; Chira, Inga; Ciobanu, Lorina (CEP Medicina, 2026)

  Introduction. In the management of chronic pancreatitis (CP), pancreatic pseudocyst (PCP) is a complication that requires the attention of surgeons, provided that it is non-neoplastic, recurrent, >6 cm in size, persists ...
• Implementing regenerative medecine across surgical pathways in liver cirrhosis 

  Negarî, Nadejda; Minchevici, Delia; Cazacov, Vladimir; Nacu, Viorel (CEP Medicina, 2026)

  Introduction: Liver cirrhotic patients often face surgical and interventional procedures, such as hepatectomy with modulation of future liver remnant, portoenterostomy in cases of biliary atresia, transjugular intrahepatic ...
• Translational perinatal medicine in non-immune fetal hydrops: from prenatal to modern cellular therapies 

  Neagu, Anastasia (CEP Medicina, 2026)

  Introduction. Non-immune fetal hydrops (NIHF) represents one of the most severe conditions in fetal medicine, characterized by the pathological accumulation of fluid in at least two fetal compartments and associated with ...
• Perinatal stem cells in regenerative medecine and transplantation: current applications and future perspectives 

  Mudzhuk, Alona; Nacu, Viorel (CEP Medicina, 2026)

  Introduction. The preservation of perinatal biological materials - umbilical cord blood, umbilical cord tissue, and placental tissue - has become one of the most important developments in modern preventive and regenerative ...
• Restoring thyroid function with tissue-engineered products after total thyroidectomy 

  Minchevici, Delia; Negarî, Nadejda; Bour, Alin; Gîlea, Angela; Nacu, Viorel (CEP Medicina, 2026)

  Introduction: Post-thyroidectomy hypothyroidism is a common complication of total thyroid removal, traditionally managed with lifelong hormone replacement therapy. Thyroid models developed through tissue engineering ...
• Diabetogenic efect of immunosuppressive drugs in transplant recipients 

  Mihalachi-Anghel, Maria; Bacinschi-Gheorghița, Stela; Bacinschi, Nicolae (CEP Medicina, 2026)

  Introduction. In organ transplant patients, new onset diabetes mellitus after transplantation (NODAT) has been found to be a frequent and serious complication. The use of immunosuppressive drugs after transplantation has ...
• Thirteen years of activity of the human tissue bank at the clinical hospital of orthopedics and traumatology 

  Nacu, Viorel; Stepa, Serghei; Cospormac, Igor; Cociug, Adrian; Cobzac, Vitalie; Țîmbalari, Tatiana (CEP Medicina, 2026)

  Introduction. Tissue transplantation represents an essential component of modern regenerative and reconstructive medicine. In the Republic of Moldova, this field has evolved progressively since the 1960s, beginning with ...
• First seizure in the elderly: causes, impact and perspectives 

  Dragan, Diana; Groppa, Stanislav (CEP Medicina, 2026)

  Background. In recent years, epilepsy in the elderly has emerged as a growing public health concern. The first epileptic seizure in an older adult often represents a critical juncture, both diagnostically and therapeutically, ...
• Evolutionary peculiarities of diabetes mellitus in liver cirrhosis 

  Ignat, Gloria; Bugai, Rodica (CEP Medicina, 2026)

  Background. Diabetes mellitus is a common comorbidity in patients with liver cirrhosis, negatively influencing the evolution and prognosis of the disease. Its evolutionary forms, especially hepatogenic diabetes, have ...
• Ischemic stroke in the vertebrobasilar territory: clinical and imaging examination 

  Botnaru, Anastasia; Ciobanu, Natalia (CEP Medicina, 2026)

  Background. Vertebrobasilar ischemic stroke is a major emergency, associated with a variable clinical picture and high risk of severe disability or death. Involvement of this territory may cause balance disorders, diplopia, ...
• Biomarkers with predictive role in chronic advanced liver disease 

  Buruiană, Daniela; Țurcanu, Adela (CEP Medicina, 2026)

  Background. Von Willebrand factor (VWF) is currently considered a biomarker of endothelial dysfunction, its determining role in the evolution of advanced chronic liver disease being highlighted, so that its high concentration ...
• Evaluation of metabolic syndrome components in patients with GERD 

  Postovanu, Alexandru; Stoica, Mihaela; Sârbu, Oxana; Calin, Ghenadie; Istrati, Valeriu (CEP Medicina, 2026)

  Background. Gastroesophageal reflux disease (GERD), with a prevalence of 10–30% worldwide, is associated with metabolic syndrome (MetS) in 30–50% of cases. The components of MetS - obesity, hyperglycemia and dyslipidemia ...
• Potential risk factors in MDR-TB patients with acquired resistance to who group a second-line drugs 

  Mukherjee, Tishya; Tewatia, Krishan; Chesov, Dumitru (CEP Medicina, 2026)

  Background. Acquired Resistance to WHO Group A second-line drugs like bedaquiline and linezolid is a new threat to treatment outcomes in patients with multi-drug resistant tuberculosis (MDR-TB). To improve treatment ...
• Silent but rising: thyroid cancer epidemiology in Moldova 

  Nizamudeen, Fathima; Motreac, Cristina (CEP Medicina, 2026)

  Background. Thyroid cancer, the leading endocrine malignancy globally, reflects a paradox of rising incidence and low mortality often linked to overdiagnosis and gender-linked disparities. The demographic and socioeconomic ...
• The rate of progression of chronic kidney disease based on etiology 

  Tritar, Mustapha; Sasu, Dorian (CEP Medicina, 2026)

  Background. Chronic kidney disease (CKD) progression varies by etiology: diabetic nephropathy, hypertensive nephrosclerosis, glomerulonephritis and polycystic kidney disease. Proteinuria and hypertension accelerate renal ...
• Particularities of joint affection in osteoarthrosis deformants in different age groups 

  Ambros, Ana-Maria; Nestor, Maria; Deseatnicova, Elena (CEP Medicina, 2026)

  Background. Osteoarthritis (OA) is a chronic degenerative joint disease affecting the cartilage and subchondral bone. Its incidence is increasing among young adults due to obesity, mechanical overload, and genetic factors. ...
• Effectiveness of different treatment regimens in H. pylori eradication – local clinical experience 

  Surguci, Doina; Dumbrăveanu, Ion; Tcaciuc, Eugen (CEP Medicina, 2026)

  Background. The eradication of H. pylori infection remains a challenge in medical practice, especially in the context of increasing antimicrobial resistance. It is assumed that in the Republic of Moldova, the infection ...
• Recurrent pulmonary tuberculosis associated with neoplastic process and severe comorbidities 

  Vatavu, Nicoleta; Gumeniuc, Cristina; Roșcovan, Gheorghe; Niguleanu, Adriana (CEP Medicina, 2026)

  Background. Pulmonary tuberculosis (TB) common recurs in immunocompromised patients with multiple comorbidities, severe nutritional impairment. The coexistence of pulmonary oncological pathology complicates differential ...

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