• Assessment of the cases of postpartum hemorrhage in multiparous women 

  Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
• Adeno-associated virus (AAV) - based gene therapies for retinal diseases 

  Ciolac, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Retinal degeneration and macular dystrophies are the leading causes of visual acuity loss and blindness in middle-aged people worldwide. Existing treatment, although considered effective, often does not lead ...
• Cystic fibrosis: current therapeutic targets based on symptoms occurred due to specific CFRT gene mutations 

  Caraman, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Cystic fibrosis (henceforth CF) is autosomal recessive disease involving mucus and sweat producing cells affecting multiple organs with lungs most severely affected leading to death in 90% of patients . A ...
• Fundoplication-induced hyperinsulinemic hypoglycemia 

  Bogdanov, Alan; Louka, George (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Hypoglycemia is often diagnosed in diabetic patients; however, this diagnosis is far rarer in non-diabetic patients. Hypoglycemia in non-diabetic persons is polyetiological. Patients often require an extensive ...
• A case study of cardiovascular disorders and its consequences in a patient with diabetes mellitus type 2 with metabolic dyslipidemia 

  Joseph, Daniel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The major aim of this case study is to analyse and understand the complicated relationship between cardiovascular disease, in a patient diagnosed with diabetes mellitus type 2 with a mixed complication stage ...
• A case of suspected lipodystrophy in an insulinresistant patient 

  Tishya, Mukherjee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Lipodystrophy syndrome, a rare disease associated with leptin deficiency and characterized by disproportionate fat loss, is linked to me tabolic disorders like dyslipidemia and severe insulin resistance. It ...
• Prevalence of POAF following cardiac surgery and comparative study on the preferred treatment modalities 

  Joy, Anugrah (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postoperative atrial fibrillation (POAF) is a common arrhythmia after cardiac surgery, with an incidence ranging from 10-65%. It is more common in older patients and noncardiac surgery patients. POAF usually ...
• The correct early diagnosis established by the multidisciplinary team is the key to success in the treatment of the post-myocardial infarction patient, complicated with renal infarction and pneumonia-infarction 

  Gobjila, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. According to the ESC guideline for the management of Acute Coronary Syndrome (ACS) it meets a spectrum of conditions, from symptoms and signs, with or without 12-lead ECG changes and with or without positive ...
• The connection between the treatment of hypothyroidism with levothyroxine and its effects on the cardiovascular system 

  Ciorici, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Hypothyroidism is a common clinical condition. Thyroid hormones have multiple effects on the function of the cardiovascular system. Aim of study. Literature analysis to determine the relationship between ...
• Epidemiological and clinical aspects of indolent extranodal non-Hodgkin's lymphoma in the Republic of Moldova 

  Josanu, Marina; Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Non-Hodgkin's lymphoma (NHL)-lymphoproliferative tumors that are histologically and biologically heterogeneous. The most common subtypes of indolent NHL being follicular lymphoma (FL), marginal zone lymphoma ...
• From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 

  Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
• Bioethical aspects of the rehabilitation of patients with type 2 diabetes in conditions of anti-pandemic restrictions 

  Croitoru, Vera (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Rehabilitation is essential for many health conditions such as acute stroke, cardiac events and endocrine diseases and others. It is estimated that due to the SARS COV-2 pandemic, an estimated range of 1.3–2.2 ...
• The involvement of micro-RNAs in cardiovascular pathologies 

  Bairamculov, Azamat (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Micro-RNAs are short molecules of ribonucleic acid with significant regulatory functions in controlling gene expression within eukaryotic cells. These small molecules play a crucial role in post-transcriptional ...
• Nonalcoholic fatty liver disease pathogenic mechanisms and non-invasive diagnosis 

  Uncu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Non-alcoholic fatty liver disease (NAFLD) affects a quarter of the world's population and is one of the most common liver diseases. It can progress to liver cirrhosis and hepatocellular carcinoma (HCC). ...
• Clinical characteristic of adults hospitalized with COVID-19 in the Republic of Moldova 

  Ciobanu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The global impact of the unprecedented COVID-19 pandemic has prompted an urgent need to comprehensively understand the clinical characteristics of affected individuals for effective healthcare management. ...
• The role of JAK-inhibitors in the treatment of rheumatoid arthritis 

  Cozma, Octavian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Rheumatoid arthritis is a systemic chronic autoimmune inflammatory disease characterized by persistent destructive synovitis with extra-articular manifestations. Despite the recent development and recommended ...
• Genetic aspects of thrombophilia in pregnancy 

  Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
• Hormonal disturbances in the polycystic ovary syndrome 

  Colin, Mihai; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Polycystic ovary syndrome (PCOS) is an endocrine pathology that affects women of reproductive age. Hormonal disturbances in the PCOS are the central cause of heterogenous clinical presentation involving ...
• Obesity: particular complications in pregnant women 

  Sofonov, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Obesity is a nosological entity determined by the body's psychosomatic imbalance, resulting in energy excess and pathological expansion of adipose tissue causing severe complications and increased overall ...
• Clinical ”Odyssey” in Wilson's disease patients from the Republic of Moldova 

  Cumpătă, Veronica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Wilson's disease (WD) presents high clinical heterogeneity, independent of age and sex. In our country, it is the first study that analyzes the phenotype of patients with this genetic disorder. Aim of study. ...

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