• Assessment of the cases of postpartum hemorrhage in multiparous women 

  Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
• Gluten intolerance. Celiac disease 

  Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
• The influence of type 2 pregestational diabetes mellitus on the fetus 

  Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
• The role of gut microbiota metabolites in atherosclerosis 

  Berliba, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Changes in gut microbiota metabolites(GMM) is linked to the development of CVD, which includes atherosclerosis, hypertension, ...
• Mechanisms of action and metabolic effects of anticoagulants 

  Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
• Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 

  Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
• Biochemical aspects of malabsorption syndromes 

  Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
• The anatomical variability of the last three pairs of the intercostal arteries 

  Croitoru, Dan; Coșciug, Stanislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The intercostal arteries are of vital significance in the vascularisation of the intercostal musculature, fascia and the ribs. The last three pairs are involved in the blood supply of the antero-lateral ...
• Variational aspects of the deep femoral artery 

  Nacu, Zinaida (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The deep femoral artery (DFA), also known as the deep artery of the thigh, classically, originates from the lateral semi-circumference of the femoral artery (FA), in the distal direction, at a distance of ...
• Estrogen therapy - metabolic and clinical consequences 

  Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
• Incidence, risk factors, and complications of cardiovascular system in patient with Graves disease 

  Saravanane, Essaimathi (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Graves' disease, a common autoimmune illness characterized by a rise in thyroid hormone production, has been widely researched in terms of its effects on the thyroid gland. However, a new study emphasizes the ...
• Exploring the role of N-terminal pro-brain natriuretic peptide as a diagnostic biomarker in Kawasaki disease 

  Duca, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is an acute febrile illness of unknown cause that stands out as a unique and challenging pediatric vasculitis, characterized by acute ...
• Autism spectrum disorder - a comprehensive literary review 

  Lupașcu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Autism spectrum disorder (ASD) can be identified from other neurodevelopmental disorders by its distinctive combination of symptoms: difficulties in social interaction and communication, repetitive, stereotyped, ...
• Metabolic peculiarities of immunotherapeutic medicines (chimeric antigen receptor t cells) used in cancer treatment (b-cell acute lymphoblastic leukemia) 

  Sluchin, Andrei (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. In the dynamic realm of cancer therapeutics, many studies explore the metabolic nuances of Chimeric Antigen Receptor (CAR) T-cell therapy in treating B-cell acute lymphoblastic leukemia (B-ALL). Understanding ...
• The interplay of growth hormone, insulin-like growth factors, and cancer susceptibility: a medical perspective 

  Briceag, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. GH and IGF-I, known for promoting growth, are under scrutiny for their potential involvement in cancer progression. While we understand their normal effects, the disruption caused by these factors and their ...
• Autoimmune polyglandular syndrome type 2: a case report 

  Surguci, Doina; Dumbrăveanu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Autoimmune polyglandular syndromes are classified into two major subtypes, each characterized by involvement of specific endocrine glands. The autoimmune polyglandular syndrome type 2 is defined by the presence ...
• The role of leptin in the pathogenesis of metabolic dysfunction-associated fatty liver disease 

  Darii, Felicia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Metabolic dysfunction-associated fatty liver disease (MAFLD) has become one of the leading causes of end-stage liver disease. Its pathogenesis is not fully understood, but leptin may contribute to the development ...
• Psycho-emotional state before and after the injectable procedure 

  Cazacu, Victoria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Persons who would like a change of the exterior, including those who are often afraid to start the aesthetic intervention for reasons when they want to stop the procedure, will look worse or are afraid of the ...
• GLUTs genetic defects as causes of diabetes 

  Ciuchitu, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Diabetes mellitus (DM) is a chronic disease marked by insulin secretion or action defects. The cause of diabetes can be genetic defects of glucose transporters – GLUT, the most characteristic being the GLUT2 ...
• Recurrent hypoglycemia in patients with diabetes and liver cirrhosis – a real therapeutic challenge 

  Sîrbu, Felicia; Vieru, Daniela; Gușanu, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Diabetes is a global health problem, currently about 540 million adults suffer from diabetes, according to data published by the International Diabetes Federation. Approximately 20-60% of patients with cirrhosis ...

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