• Assessment of the cases of postpartum hemorrhage in multiparous women 

  Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
• Adeno-associated virus (AAV) - based gene therapies for retinal diseases 

  Ciolac, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Retinal degeneration and macular dystrophies are the leading causes of visual acuity loss and blindness in middle-aged people worldwide. Existing treatment, although considered effective, often does not lead ...
• Cystic fibrosis: current therapeutic targets based on symptoms occurred due to specific CFRT gene mutations 

  Caraman, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Cystic fibrosis (henceforth CF) is autosomal recessive disease involving mucus and sweat producing cells affecting multiple organs with lungs most severely affected leading to death in 90% of patients . A ...
• Treatment of generalized nodal non-Hodgkin's lymphomas 

  Dunas, Adriana; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Non-Hodgkin's lymphomas (NHL) comprise a diverse group of malignant lymphoid tumors, with multiple distinct histological and immunohistochemical subtypes. Understanding and differentiating these subtypes is ...
• Prevalence of POAF following cardiac surgery and comparative study on the preferred treatment modalities 

  Joy, Anugrah (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postoperative atrial fibrillation (POAF) is a common arrhythmia after cardiac surgery, with an incidence ranging from 10-65%. It is more common in older patients and noncardiac surgery patients. POAF usually ...
• The correct early diagnosis established by the multidisciplinary team is the key to success in the treatment of the post-myocardial infarction patient, complicated with renal infarction and pneumonia-infarction 

  Gobjila, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. According to the ESC guideline for the management of Acute Coronary Syndrome (ACS) it meets a spectrum of conditions, from symptoms and signs, with or without 12-lead ECG changes and with or without positive ...
• Epidemiological and clinical aspects of indolent extranodal non-Hodgkin's lymphoma in the Republic of Moldova 

  Josanu, Marina; Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Non-Hodgkin's lymphoma (NHL)-lymphoproliferative tumors that are histologically and biologically heterogeneous. The most common subtypes of indolent NHL being follicular lymphoma (FL), marginal zone lymphoma ...
• From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 

  Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
• Immunohistochemical particularities as prognostic factors in diffuse large B-cell non-Hodgkin lymphoma 

  Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Diffuse Large B-Cell Lymphoma (DLBCL), the most common type of NonHodgkin Lymphoma (NHL) globally, is classified into two distinct biological categories based on the gene expression profile (GEP): the germinal ...
• Treatment of Hodgkin’s lymphoma in advanced stages 

  Marandici, Daniel; Musteață, Larisa; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Hodgkin's lymphoma is a relatively frequent neoplasm of the lymphatic system representing one of the most common types of cancer in young adults. Hodgkin's lymphoma is an aggressive, clinico-pathologically ...
• Congenital anomalies in newborns: syndactyly 

  Zveaghinteva, Ludmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The name of “hand” comes from the Latin “manus”, derived from “manipulus”. The hand is the most perfected segment of the human locomotor system and is a complex organ made up of 27 bones, 27 joints and 19 ...
• The medical rehabilitation program improves the quality of life of patients with AMI 

  Badan, Maxim; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The incidence of acute myocardial infarction (AMI) is continuously increasing. In 2019, mortality from cardiovascular diseases reached 9 million people each year in Europe. Cardiovascular diseases are the ...
• Impact of chronic obstructive pulmonary disease on quality of life 

  Lupu, Liliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Chronic Obstructive Pulmonary Disease (COPD) is the leading cause of morbidity and mortality worldwide. According to the World Health Organization, globally, COPD is the third leading cause of death, accounting ...
• Pulmonary tuberculosis with pneumonia-like onset in post-pandemic era: case series 

  Potop-Rotari, Dorina; Amoașii, Anastasia; Hapun, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Outbreak of pulmonary tuberculosis (TB) in post-COVID-19 era represents a real medical and social problem. It remains a diagnostic challenge due to a variety of respiratory (pneumonia, malignancy etc.) and ...
• The influence of obesity on the quality of life in patients with gastro-esophageal reflux disease 

  Stoica, Mihaela; Munteanu, Ecaterina; Neagu, Stepan; Sârbu, Oxana; Calin, Ghenadie; Scurtu, Alina; Scorpan, Anatolie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Obesity or exaggerated growth of adipose tissue according to body mass index (BMI) has shown an increase in the prevalence of gastroesophageal reflux disease (GERD), which significantly affects the quality ...
• Hypereosinophilic syndrome - diagnostic challenges in allergic patients 

  Chiosa, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Eosinophilia is a common laboratory manifestation associated with multiple diseases (allergic, parasitic, infectious or oncological diseases). Eosinophilia is an increase in the absolute values of eosinophils ...
• Post-COVID-19 sequelae 

  Focsa, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. COVID-19 is a pandemic infection caused by the novel severe acute respiratory syndrome coronavirus-2, affecting millions of people worldwide and having devastating consequences on health systems, the economy, ...
• Chronic obstructive pulmonary disease and depression 

  Avadănii, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
• Diagnostic accuracy of Xpert Ultra for microbiological confirmation of pulmonary tuberculosis in patients with paucibacillary disease 

  Sîrbu, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Worldwide, up to one-third of pulmonary tuberculosis patients are missed for microbiological confirmation. Assessment of specimens obtained during bronchoscopy is one of the well-recognized methods that can ...
• Laboratory markers in the diagnosis of hereditary gluten intolerance 

  Rotari, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...

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