• Assessment of the cases of postpartum hemorrhage in multiparous women 

  Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
• Gluten intolerance. Celiac disease 

  Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
• The influence of type 2 pregestational diabetes mellitus on the fetus 

  Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
• The role of gut microbiota metabolites in atherosclerosis 

  Berliba, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Changes in gut microbiota metabolites(GMM) is linked to the development of CVD, which includes atherosclerosis, hypertension, ...
• Mechanisms of action and metabolic effects of anticoagulants 

  Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
• Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 

  Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
• Biochemical aspects of malabsorption syndromes 

  Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
• Variational aspects of the deep femoral artery 

  Nacu, Zinaida (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The deep femoral artery (DFA), also known as the deep artery of the thigh, classically, originates from the lateral semi-circumference of the femoral artery (FA), in the distal direction, at a distance of ...
• Neurosyphilis case report 

  Rotari, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Neurosyphilis is relatively rare in last decades, due to the epidemiological measures in force. Because of the variety of clinical manifestations, from mild behavioral disturbances to paralysis and death, ...
• Estrogen therapy - metabolic and clinical consequences 

  Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
• Recurrent hypoglycemia in patients with diabetes and liver cirrhosis – a real therapeutic challenge 

  Sîrbu, Felicia; Vieru, Daniela; Gușanu, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Diabetes is a global health problem, currently about 540 million adults suffer from diabetes, according to data published by the International Diabetes Federation. Approximately 20-60% of patients with cirrhosis ...
• Clinical characteristics of children hospitalized with covid 19 in the Republic of Moldova 

  Babilev, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The World Health Organization named 2019 the year of global emergency. The disease that left its mark on humanity caused by the SARS-CoV-2 virus was called COVID-19. In the Republic of Moldova, 5.1% of the ...
• Interplay of glucose metabolism and its influence on myopia development 

  Dacu, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Available data suggests that by the year 2050, approximately half of the global population will experience nearsightedness, marking myopia as a genuine worldwide epidemic. To this day, the impact of nutrition ...
• Unlocking the shield: examining retinal protection via macular carotenoids' antioxidant capacity 

  Buraga, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The human retina, crucial for vision, is highly susceptible to oxidative damage due to its exposure to light and high metabolic activity. Three macular xanthophylls (MXs) – zeaxanthin (Z), lutein (L), and ...
• Clinical manifestations and complications of acromegaly 

  Doicov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Acromegaly is a rare disease that requires a specific approach in evaluating clinical symptoms and complications. Aim of study. Evaluation of clinical manifestations, onset and complications of acromegaly for ...
• The biochemical relationship between stress and autoimmunity 

  Buciumaș, Aurelia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Stress is a state of concern or psychological tension which appears because of a difficult situation. Stress is a normal response of our body that helps us survive all the challenges and threats of our ...
• Genetic factors responsible for ovarian reserve 

  Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
• The cardiotoxicity of local anesthetics 

  Talasimov, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
• Stress and neuronal cell death: pathogenetic mechanisms, management and treatment 

  Postolache, Danu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. The nervous system is the most complex organ in the human body, as structurally – consisting of billions of neurons, as functionally – being responsible for cognition, behavior, and conscience. Therefore, the ...
• Stroke in pregnancy and postpartum 

  Curnic, Andreea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)

  Introduction. Stroke is a medical emergency that requires urgent care and treatment. As everyone, regardless of age, gender or health, can experience this condition, pregnant women can have it as well. In addition to major ...

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