MedEspera 2024: Recent submissions

  • Assessment of the cases of postpartum hemorrhage in multiparous women 
    Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
  • Unraveling the molecular signaling pathways in glial tumors with methylated MGMT promoters 
    Croitoru, Dan; Andronachi, Victor; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Most gliomas are typically assessed using imaging methods. A recent advancement in this regard involves the integration of biomarkers in conjunction with imaging techniques, such as 18F-FDG-PET-based radiomics ...
  • Clinical characteristics of children hospitalized with covid 19 in the Republic of Moldova 
    Babilev, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The World Health Organization named 2019 the year of global emergency. The disease that left its mark on humanity caused by the SARS-CoV-2 virus was called COVID-19. In the Republic of Moldova, 5.1% of the ...
  • From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 
    Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Genetic variants of COMT gene expression and influence on pain perception 
    Crasevici, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Catechol-O-methyltransferase (COMT) is a pivotal enzyme responsible for deactivating biologically active catechols, including crucial neurotransmitters such as dopamine, norepinephrine, and adrenaline. These ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Personalized medicine and cardiovascular diseases 
    Sooltan, Abdool Rahim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There was a remarkable growth in scientific publication on personalized medicine within the past few years in the field of cardiovascular disease. In the era of personalized/precision medicine the combination ...
  • Unmasking the technological innovations: insights through the encode project 
    Kuzhipurayidathil, Vijayakumar Anaswara (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Encode (Encyclopaedia of DNA Elements) Project, launched over a decade ago has played a significant role in the research world by aiding in the elucidation of the intricate human genome and its fundamental ...
  • Bone scintigraphy - the coner stone in treatment management for osteophilic neoplasms 
    Gorea, Diana Valentina; Asavei, Letitia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bone scintigraphy is a nuclear medicine imaging investigation that studies the biodistribution of a radiotracer at the skeletal level. It is considered to be a very sensitive technique due to the fact that ...
  • The role of cognitive factors and respiratory dysfunction in chronic pain 
    Cuzmuc, Artiom (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In the last two decades the thorough study of cognition and breathing in the context of chronic pain have found a crucial role in the adaptation of new therapies for the management of CP ( chronic pain). The ...
  • Anosmia – a neurological complication in Covid-19 
    Markovich, Dmitry (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anosmia is a partial or complete loss of smell. It has gained great attention during COVID-19 pandemic, as many infected individuals have reported distorted sense of smell. Anosmia is a condition that can ...
  • Frequency and characteristics of common cutaneous vesiculobullous disorders in the Republic of Moldova 
    Robu, Felicia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The vesiculobullous pattern represents a large group of predominantly immunerelated disorders, morphologically characterized by blistering eruptions localized within or below the epidermis. In this study, we ...
  • A case report of single ventricle - peculiarities of evolution in a 8-month-old child 
    Gorbatenco, Daniela; Mindru, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Single ventricle is a type of malformation when the heart has both normally developed atria, but they open into a single ventricular chamber. The disease has a multifactorial nature in which both genetic and ...
  • Transthyretin cardiac amyloidosis and bone scintigraphy: state of the art detection in rare diseases 
    Asavei, Letiția; Cârciumaru, Marius; Ciocoiu-Bunilă, Ioan Vlad; Gorea, Diana Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transthyretin cardiac amyloidosis (ATTR-ca) is a rare protein deposition disease characterized by the accumulation of amyloid in the myocardium altering its function. Diagnosing it has proven to be a challenge ...
  • Burden of bullying for mental health state in children and adolescents 
    Alexeev, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. School bullying constitutes a complex and alarming societal issue that negatively impacts students worldwide. The term "bullying" refers to repeated behaviors of intimidation, aggression, or verbal and physical ...
  • The role of NO and H2S in circulatory homeostasis regulation and dysfunction 
    Eremia, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Modern concept corroborates vascular endothelium as a crucial pillar regarding the control of a lot of vascular derived functions in circulatory homeostasis, such as: basal vascular tone and blood pressure, ...
  • Infectious complications after caesarean delivery 
    Zuico, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cesarean delivery, also known as a C-section, is characterized by the delivery of a fetus through surgical incisions performed on both the abdominal wall (laparotomy) and the uterine wall (hysterotomy). ...
  • The impact of COVID-19 disease on platelets and coagulation 
    Vartic, Iana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Platelets are formed elements of blood that play an important role in blood clotting. As the main mediator of thrombus formation, platelets have become one of the key aspects in the study of SARS-CoV-2. ...

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