MedEspera 2024: Recent submissions

  • Assessment of the cases of postpartum hemorrhage in multiparous women 
    Cemortan, Maria; Bubulici, Cristina; Vicol, Maria-Magdalena; Grajdean, Elena; Scripnic, Gabriela; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is one of the leading obstetric complications, affecting 5-15% births. Being a major factor in maternal mortality and morbidity, PPH causes about 25% of maternal deaths worldwide. Aim ...
  • Gluten intolerance. Celiac disease 
    Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
  • The influence of type 2 pregestational diabetes mellitus on the fetus 
    Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
  • The role of gut microbiota metabolites in atherosclerosis 
    Berliba, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Changes in gut microbiota metabolites(GMM) is linked to the development of CVD, which includes atherosclerosis, hypertension, ...
  • Mechanisms of action and metabolic effects of anticoagulants 
    Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
  • A case of suspected lipodystrophy in an insulinresistant patient 
    Tishya, Mukherjee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lipodystrophy syndrome, a rare disease associated with leptin deficiency and characterized by disproportionate fat loss, is linked to me tabolic disorders like dyslipidemia and severe insulin resistance. It ...
  • Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 
    Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
  • Biochemical aspects of malabsorption syndromes 
    Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
  • Neurosyphilis case report 
    Rotari, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurosyphilis is relatively rare in last decades, due to the epidemiological measures in force. Because of the variety of clinical manifestations, from mild behavioral disturbances to paralysis and death, ...
  • Estrogen therapy - metabolic and clinical consequences 
    Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
  • Anatomo clinical argumentation of reflexogenic zones 
    Zaharco, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. A reflexogenic zone can be defined as a specific region of the human body that, through stimulation or pressure, can influence or trigger responses in other parts of the organism. These can be considered true ...
  • From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 
    Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
  • Immunohistochemical particularities as prognostic factors in diffuse large B-cell non-Hodgkin lymphoma 
    Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diffuse Large B-Cell Lymphoma (DLBCL), the most common type of NonHodgkin Lymphoma (NHL) globally, is classified into two distinct biological categories based on the gene expression profile (GEP): the germinal ...
  • Treatment of Hodgkin’s lymphoma in advanced stages 
    Marandici, Daniel; Musteață, Larisa; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hodgkin's lymphoma is a relatively frequent neoplasm of the lymphatic system representing one of the most common types of cancer in young adults. Hodgkin's lymphoma is an aggressive, clinico-pathologically ...
  • Congenital anomalies in newborns: syndactyly 
    Zveaghinteva, Ludmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The name of “hand” comes from the Latin “manus”, derived from “manipulus”. The hand is the most perfected segment of the human locomotor system and is a complex organ made up of 27 bones, 27 joints and 19 ...
  • The medical rehabilitation program improves the quality of life of patients with AMI 
    Badan, Maxim; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of acute myocardial infarction (AMI) is continuously increasing. In 2019, mortality from cardiovascular diseases reached 9 million people each year in Europe. Cardiovascular diseases are the ...
  • The significant impact of artificial intelligence in TAVI 
    Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, TAVI represents a benchmark in the treatment of patients with severe aortic stenosis, becoming a durable and preferred option compared to the traditional SAVR method. The success of TAVI significantly ...
  • The impact of COVID-19 on patients with non-Hodgkin lymphoma 
    Dediu, Luminița (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Patients diagnosed with coronavirus 2019 (COVID-19) disease during hematological malignancies have been described as having a poor outcome, with only a few reports specifically addressing patients with lymphoma. ...
  • Recurrent hypoglycemia in patients with diabetes and liver cirrhosis – a real therapeutic challenge 
    Sîrbu, Felicia; Vieru, Daniela; Gușanu, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes is a global health problem, currently about 540 million adults suffer from diabetes, according to data published by the International Diabetes Federation. Approximately 20-60% of patients with cirrhosis ...
  • Clinical characteristics of children hospitalized with covid 19 in the Republic of Moldova 
    Babilev, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The World Health Organization named 2019 the year of global emergency. The disease that left its mark on humanity caused by the SARS-CoV-2 virus was called COVID-19. In the Republic of Moldova, 5.1% of the ...

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