MedEspera 2024: Recent submissions

  • Clinical manifestations and complications of acromegaly 
    Doicov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acromegaly is a rare disease that requires a specific approach in evaluating clinical symptoms and complications. Aim of study. Evaluation of clinical manifestations, onset and complications of acromegaly for ...
  • Clinical and hematological features and diagnostic options in extranodal aggressive non-Hodgkin's lymphomas 
    Pîrlii, Iulius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lymphomas can be simply defined as malignant neoplasms of lymphocytes and their precursor cells. Common sites of extranodal manifestations are the gastrointestinal tract, especially the ventricle, pharynx, ...
  • Genetic factors responsible for ovarian reserve 
    Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
  • The cardiotoxicity of local anesthetics 
    Talasimov, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
  • Applicability of the CLDQ in the monitoring of patients with delta viral liver cirrhosis 
    Cebanu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The clinical burden of delta viral cirrhosis is significant in terms of health, quality of life, and economic impact on patients and society. The Chronic Liver Disease Questionnaire (CLDQ) is an instrument ...
  • Risk factors for pulmonary tuberculosis defined according to the drug-resistance profile 
    Savenco, Doina; Hujeirat, Shaher Mahmoud (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Tuberculosis (TB) represents a major health problem, listed among 30 countries with the highest burden of the drug-resistant tuberculosis (MDR-TB) and its prevalence is correlated with the risk factors such ...
  • Two ends of therapeutic response spectrum in the clinical evolution of eosinophilic pneumonitis 
    Comanac-Juratu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Eosinophilic pneumonia (EP) is a rare disorder encompassing a heterogeneous presentation. The two primary types of EP are acute eosinophilic pneumonia (AEP) and chronic eosinophilic pneumonia (CEP), both ...
  • Hereditary angioedema with C1 inhibitor deficiency 
    Butucel, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hereditary angioedema (HAE) is a rare autosomal dominant disease with deficiency or/and dysfunction of C1 inhibitor, caused by mutations in the C1-INH gene. HAE is characterized by potentially life-threatening ...
  • Comorbidities in gout 
    Praștină, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gout is a member of the microcrystalline arthritis group characterized by musculoskeletal involvement and is also associated with a high incidence of comorbidities. Serum urate concentrations in patients with ...
  • Cancer never takes a break — a new reality, the same relentless adversary 
    Luca, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lung cancer presents a significant global health challenge, posing a pervasive threat to individuals worldwide. It stands as a major concern, often linked to severe prognoses and a substantial impact on quality ...
  • Impact of new classification of copd on assessment of severity 
    Gîlca, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease is a respiratory disease caused by abnormalities of the airways, alveoli, accompanied by chronic respiratory symptoms (dyspnea, cough, expectoration), characterized by a ...
  • Pulmonary tuberculosis with chronic evolution – clinical aspects 
    Vacarciuc, Eugenia-Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Evaluating the clinical features of TB in patients with chronic pulmonary processes and the effectiveness of the administered treatment Aim of study. Pulmonary tuberculosis (TB) is a public health problem, ...
  • The diagnostic challenge in a patient with metachronous malignancies 
    Polevoi, Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Metachronous malignancies are a rare entity in clinical practice. This case report reveals interconnection between a malignant adrenal tumor diagnosed 6 years ago and a rare central bronchial carcinoid tumor ...
  • Neurological impairment in systemic lupus erythematosus 
    Dubalaru, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. SLE is a multifactorial autoimmune disease of unknown etiology, which is characterized by a diverse multisystemic effect that appears as the result of certain imperfect immunoregulatory processes. Aim of ...
  • Exploring the role of N-terminal pro-brain natriuretic peptide as a diagnostic biomarker in Kawasaki disease 
    Duca, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is an acute febrile illness of unknown cause that stands out as a unique and challenging pediatric vasculitis, characterized by acute ...
  • Metabolic peculiarities of immunotherapeutic medicines (chimeric antigen receptor t cells) used in cancer treatment (b-cell acute lymphoblastic leukemia) 
    Sluchin, Andrei (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In the dynamic realm of cancer therapeutics, many studies explore the metabolic nuances of Chimeric Antigen Receptor (CAR) T-cell therapy in treating B-cell acute lymphoblastic leukemia (B-ALL). Understanding ...
  • Variation of the mastoid segment of the facial canal and of the stylomastoid foramen 
    Ashkar, Laila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Taking into consideration that the ratio of the facial nerve iatrogenic injuries in primary mastoidectomy is 0.6%-3.7%, and a twice higher ratio of 4%-10% is reported for the revision surgery, the knowledge ...
  • Biochemical aspects of heart diseases in patients with diabetes mellitus 
    Parapuravalappil Sathyan, Krishnadas (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of diabetes mellitus is continuously increasing globally and is estimated to reach approx. 366 million by 2030. According to the latest research, the cardiovascular changes due to diabetes are ...
  • Biochemical changes of the vascular endothelium in diabetic pathology 
    Stici, Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes mellitus (DM) is a multifactorial pathology that has become a worldwide problem due to its rapid spread and progression. Persistent hyperglycemia in DM induces disruption of vascular homeostasis by ...
  • Disruption of the immune response in patients with obesity during COVID-19 
    Zahlîstnîi, Bogdan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity was one of the frequent comorbidities in hospitalized patients with SARSCoV-2 infection. The recent studies of Covid-19 outcomes have noticed a correlation between obesity and more severe clinical ...

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