MedEspera 2024: Recent submissions

  • The role of predictive factors of hemorrhagic transformation in patients with ischemic stroke undergoing intravenous thrombolysis 
    Frimu, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intravenous thrombolysis (IT) is the standard intervention for patients with ischemic stroke that demonstrates a significant rate of reduction in mortality and disability. Hemorrhagic transformation (HT) after ...
  • Endocrine changes and menstrual dysfunctions in adolescent girls with obesity 
    Solcanu, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent decades, there has been a significant increase in the obesity rate among adolescent girls. According to the specialized literature, obesity induces hormonal changes that have consequences on sexual ...
  • HPV status and associated precursor lesion in vulvar squamous cell carcinoma 
    Butnaru, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There are distinctive precursor lesions related to vulvar squamous cell carcinoma (VSCC) that are associated with high-risk human papillomavirus (HPV) type 16,18 specifically vulvar intraepithelial neoplasia ...
  • Prospects for obtaining liposomes with standardized plant extract 
    Stahi, Cristina; Yaman, Abdin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent years, scientists have shown an increasing interest in incorporating biologically active compounds extracted from plants into nanoparticle delivery systems. Examples of such delivery systems include ...
  • Anti-cancer compounds in brassica vegetables 
    Ciurea, Laura (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cancer is the main cause of mortality and morbidity worldwide. According to the World Cancer Research Fund an estimated 40% of all human cancers are related to diet. Although a large variety of therapeutic ...
  • Use of sodium-glucose cotransporter 2 inhibitors in heart failure 
    Ferdohleb, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Heart failure syndrome has been designated as a major clinical and public health problem. Ischemic cardiopathy, arterial hypertension, cardiomyopathies, myocarditis, pericarditis valvulopathies, arrhythmias, ...
  • Study on clinical cases of atopic dermatitis in children 
    Iepure, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Allergic contact dermatitis (ACD) was once considered a rarity in children, but recent estimates suggest that it affects 4.4 million children in the United States alone. Currently, there is no cure, but an ...
  • Comparative analysis of the national and international legislative framework regarding the storage of medicinal products for human use 
    Golovei, Ina; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Globally, regulating and managing medicines is vital for public health. This presentation compares how the Republic of Moldova and the European Union handle the storage and preservation of medicines. It ...
  • Antibacterial activity of basil essential oil 
    Boguș, Dorin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basil essential oil has been demonstrated to possess various beneficial properties, including analgesic, anti-inflammatory, antibacterial, hepatoprotective, and immunomodulatory effects. The multifunctionality ...
  • Action of biopharmaceutical factors on drug bioavailability 
    Andronachi, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the Food and Drug Administration (FDA), bioavailability represents the amount of active substance released from a pharmaceutical form, absorbed into the bloodstream, and reaching the site of ...
  • Drug interactions and errors in the treatment of hypertension in the elderly 
    Diaconu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hypertension is a condition in which the systolic and diastolic pressures are increased above the permissible limit. According to the European Society of Hypertension, for people without diabetes, the values ...
  • Liposome biopharmaceutic and nanoparticles in human body 
    Costea, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The use of nanotechnology in medicine, and more specifically in drug delivery, is rapidly spreading. Numerous substances are currently being researched for drug delivery and, in particular, cancer therapy. Aim ...
  • Management of postpartum hemorrhage 
    Doncilă, Ilinca (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is defined as a blood loss from the genital tract of ≥500 mL associated with vaginal delivery or greater than 1000 mL following cesarean section, which requires emergency hysterectomy ...
  • A comparative study on the optimal Shunt types for surgical management of TOF 
    Manoj, Rachel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Tetralogy of Fallot (TOF) is a congenital cardiac anomaly with intricate structural aberrations. Surgical approaches for TOF range from immediate repair to staged methodology. Blalock et al. pioneered the ...
  • Cardiac abscess, fatal complication in infective endocarditis, clinical case 
    Spatari, Anastasia; Rusu, Adriana; Samohvalov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of infective endocarditis (IE) is 3-10 per 100.000 people/year, the disease causing a high mortality rate (30%) in 1 month. The incidence of cardiac abscesses among patients with IE is between ...
  • Importance of an imagistic examination of temporomandibular joint 
    Vahnovan, Ioan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Medical imagistic techniques have evolved significantly in recent years, which has led to an increase in both the quality of the images obtained and the quality and accuracy of diagnosis. Therefore, imagistic ...
  • Immune system response to orthodontic tooth movement 
    Sîrbu, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Dental movements during orthodontic treatment are generated by a mechanical force that induces an aseptic inflammatory response in the tissues of the periodontal system, which subsequently generates the process ...
  • Icon-an innovative approach to fluorosis treatment 
    Leșan, Vladislava (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Minimally invasive treatment serves as a progressive outlook in the field of dentistry, and it has valuable scientific importance. It serves as a support to create adequate conditions for the maximum preservation ...
  • Challenging clinical case 
    Savov, Petru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Atrial septal defect is a congenital disease characterized by the presence of communication between the right and left atria, leading to abnormal blood movement at the heart level. This defect occurs in 1 out ...
  • Descriptive study of diagnostic findings in male with severe oat syndrome and azoospermia 
    Palamarciuc, Luminita; Dumbrăveanu, Ion; Arian, Iurii (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. It has been established that one of the most prevalent causes of male subfertility is oligoasthenoteratozoospermia (OAT). About 1% of men in the general population and 10%– 15% of men who are infertile have ...

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