MedEspera 2024: Recent submissions

  • Anatomical variants of the median sacral artery 
    Rotaraș, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Knowing the anatomical variants of the median sacral artery has the applied significance, since it is necessary for the surgeons when choosing the operational techniques, in order to ensure the safe access ...
  • Corpus callosum agenesis in morphoclinical aspect 
    Rotaraș, Arina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Agenesis of the corpus callosum (ACC) is a congenital brain anomaly, characterized by the absence of commissural fibers connecting the two large hemispheres of the brain. This can be partial or total and can ...
  • From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 
    Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
  • Bioethical aspects of the rehabilitation of patients with type 2 diabetes in conditions of anti-pandemic restrictions 
    Croitoru, Vera (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rehabilitation is essential for many health conditions such as acute stroke, cardiac events and endocrine diseases and others. It is estimated that due to the SARS COV-2 pandemic, an estimated range of 1.3–2.2 ...
  • The involvement of micro-RNAs in cardiovascular pathologies 
    Bairamculov, Azamat (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Micro-RNAs are short molecules of ribonucleic acid with significant regulatory functions in controlling gene expression within eukaryotic cells. These small molecules play a crucial role in post-transcriptional ...
  • Nonalcoholic fatty liver disease pathogenic mechanisms and non-invasive diagnosis 
    Uncu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-alcoholic fatty liver disease (NAFLD) affects a quarter of the world's population and is one of the most common liver diseases. It can progress to liver cirrhosis and hepatocellular carcinoma (HCC). ...
  • Clinical characteristic of adults hospitalized with COVID-19 in the Republic of Moldova 
    Ciobanu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The global impact of the unprecedented COVID-19 pandemic has prompted an urgent need to comprehensively understand the clinical characteristics of affected individuals for effective healthcare management. ...
  • The role of JAK-inhibitors in the treatment of rheumatoid arthritis 
    Cozma, Octavian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis is a systemic chronic autoimmune inflammatory disease characterized by persistent destructive synovitis with extra-articular manifestations. Despite the recent development and recommended ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
  • Hormonal disturbances in the polycystic ovary syndrome 
    Colin, Mihai; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Polycystic ovary syndrome (PCOS) is an endocrine pathology that affects women of reproductive age. Hormonal disturbances in the PCOS are the central cause of heterogenous clinical presentation involving ...
  • Obesity: particular complications in pregnant women 
    Sofonov, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a nosological entity determined by the body's psychosomatic imbalance, resulting in energy excess and pathological expansion of adipose tissue causing severe complications and increased overall ...
  • Clinical ”Odyssey” in Wilson's disease patients from the Republic of Moldova 
    Cumpătă, Veronica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wilson's disease (WD) presents high clinical heterogeneity, independent of age and sex. In our country, it is the first study that analyzes the phenotype of patients with this genetic disorder. Aim of study. ...
  • Impact of chronic obstructive pulmonary disease on quality of life 
    Lupu, Liliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Obstructive Pulmonary Disease (COPD) is the leading cause of morbidity and mortality worldwide. According to the World Health Organization, globally, COPD is the third leading cause of death, accounting ...
  • The influence of obesity on the quality of life in patients with gastro-esophageal reflux disease 
    Stoica, Mihaela; Munteanu, Ecaterina; Neagu, Stepan; Sârbu, Oxana; Calin, Ghenadie; Scurtu, Alina; Scorpan, Anatolie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity or exaggerated growth of adipose tissue according to body mass index (BMI) has shown an increase in the prevalence of gastroesophageal reflux disease (GERD), which significantly affects the quality ...
  • Hypereosinophilic syndrome - diagnostic challenges in allergic patients 
    Chiosa, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Eosinophilia is a common laboratory manifestation associated with multiple diseases (allergic, parasitic, infectious or oncological diseases). Eosinophilia is an increase in the absolute values of eosinophils ...
  • Applicability of the CLDQ in the monitoring of patients with delta viral liver cirrhosis 
    Cebanu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The clinical burden of delta viral cirrhosis is significant in terms of health, quality of life, and economic impact on patients and society. The Chronic Liver Disease Questionnaire (CLDQ) is an instrument ...
  • Chronic obstructive pulmonary disease and depression 
    Avadănii, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
  • Diagnostic accuracy of Xpert Ultra for microbiological confirmation of pulmonary tuberculosis in patients with paucibacillary disease 
    Sîrbu, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Worldwide, up to one-third of pulmonary tuberculosis patients are missed for microbiological confirmation. Assessment of specimens obtained during bronchoscopy is one of the well-recognized methods that can ...
  • Laboratory markers in the diagnosis of hereditary gluten intolerance 
    Rotari, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...
  • Consequences of pulmonary hypertension and rightsided heart failure 
    Ursu, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pulmonary hypertension (PH) is common in several pathologies and maintains high levels of morbidity and mortality. In PH the main consequence is right heart failure, which leads to complex clinical syndrome ...

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