MedEspera 2024: Recent submissions

  • Vitamin D metabolism in hepatorenal syndrome 
    Harees, Noushad Juguma (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hepatorenal syndrome (HRS) is a consequence of liver cirrhosis, which is the final stage of chronic liver disease with irreversible damage and the existence of regenerating nodules. Renal function is disturbed ...
  • Bullous pemphigoid, clinical aspects and treatment 
    Caradjova, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bullous pemphigoid is a chronic, potentially fatal autoimmune skin disease that results in generalized pruritic bullous eruptions in older patients. Local and systemic glucocorticosteroid drugs are prescribed ...
  • Medical and social patterns of pelvic inflammatory disease in the Republic of Moldova 
    Căldare, Arina; Grăjdean, Victor; Vicol, Adrian; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pelvic inflammatory disease (PID) represents a significant medical and social problem. It encompasses conditions such as endometritis, salpingitis, hydrosalpinx, pyosalpinx, and tubo-ovarian abscess. The ...
  • Application of virtual reality (VR) in the planning and simulation of urgent neurosurgical interventions 
    Todica, Vladislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Emergency neurosurgery is required for acute cerebrovascular disorders, intracranial and spinal cord traumas, and pre-cerebral artery occlusion/stenosis. It requires immediate and accurate management. Virtual ...
  • Chorio-villous mesenchymal stromal dysplasia in the course of pregnancies 
    Grosu, Eugenia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stromal dysplasia is a developmental anomaly of the placenta that is characterized microscopically by dilated stem villi with a myxoid or hydropic appearance, cisterna lacunae, and lack of ...
  • Case report of a perforated intrauterine device into sigmoid colon 
    Prepeliță, Mădălina; Lavric, Irina; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intrauterine devices (IUD) have become one of the most popular birth control methods worldwide. Uterine perforation is an uncommon complication of IUD, with an incidence 1: 1,000 insertions. Perforation may ...
  • Hemostasis disorders in cardiovascular pathologies and circulatory markers 
    Păvăleanu, Iulian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hemostasis as an important compartment of general homeostasis plays a crucial role in regulation of blood fluidity and vascular wall defect closing and recovery. However, hemostasis disorders accompanied with ...
  • Unilateral sensorineural deafness contemporary aspects of etiopathogenesis, diagnosis and treatment 
    Prisăcaru, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Unilateral sensorineural hearing loss (SNHL) affects people of any age, can present as an acute or progressive process, and can range from mild to profound. Although the vast majority of cases have an unknown ...
  • Etiological, diagnostic and treatment aspects of chronic laryngitis 
    Bragari, Dan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Inflammatory processes affecting the upper respiratory tract can simultaneously exert a significant influence on the larynx and the surrounding mucosal surfaces. Inflammation in the larynx can be the direct ...
  • An in-depth investigation of synchronous multiple primary tumours (multicentric and bivalent) in the pancreas and colon 
    Cozma Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Multiple primary synchronous malignancy refers to the development of multiple cancerous growths in one or more organs, which are identified within a timeframe of 2-6 months (according to SEER-IARC/IARC). The ...
  • Coronary perfusion: regulation and mechanisms of disorders 
    Bria, Ilie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Coronary perfusion is a complex phenomenon ensuring the myocardial supply with oxygen and nutrients which is dependent on 2 major factors, such as myocardial compliance and feasibility of coronary arteries ...
  • Empty nose syndrome 
    Axenti, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Empty nose syndrome (ENS) is considered primarily an iatrogenic pathology, secondary to surgical treatment on the middle and lower nasal cornet. The frequency of ENS is not known exactly, several studies have ...
  • Otomycosis: symptoms, causes and treatment 
    Budu, Ana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Otomycosis is an isolated fungal infection of the external acoustic meatus. The causative strains that form biofilm inside the ear canal are mostly Aspergillus and Candida. Fungal external otitis has a worldwide ...
  • Distant complications of chronic tonsillitis 
    Lisevici, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic tonsillitis is a persistent inflammation of the palatine tonsils, often marked by recurrent acute episodes of tonsils inflammation, known as angina. While the condition primarily affects the throat, ...
  • Rhinopneumometry 
    Cucerenco, Jana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rhinopneumometry is an objective method of investigating nasal function, which allows to evaluate the capacity of the nasal passages and to determine possible nasal breathing disorders. This method is widely ...
  • Congenital heart disease left-to-right shunt 
    Perumal, Kishorebisel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The congenital heart condition, known as cardiac septal defect, involves lesions in the atrial or ventricular septum, significantly impacting infant and child mortality. This malformation stems from disrupted ...
  • Evaluation of adiposity indices in pediatric rheumatological disorders 
    Cepraga, Victoria; Nedealcova, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Body Mass Index (BMI) is currently the most used indicator that assesses the nutritional status of children and adults, but it cannot fully reflect the difference between excess adipose tissue and that ...
  • Emicizumab in pediatric hemophilia a: a case study 
    Miaun, Livia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The development of inhibitors that neutralize the function of clotting factor VIII is currently the most challenging complication associated with the hemophilia A treatment. Emicizumab is a humanized bispecific ...
  • Cardiovascular damage in children with systemic lupus erythematosus 
    Muringakodan, Najmulhudha (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Juvenile Systemic Lupus Erythematosus (jSLE) is a rare autoimmune disorder affecting multiple systems in children and adolescents causing unique challenges in diagnosis and management. Cardiovascular ...
  • Microscopic and ultrastructural characteristics of keratinocytes 
    Coltuc, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Keratinocytes are the principal epidermal cells, constituting the outermost layer of the skin - the external and largest organ of the human body. Epidermal keratinocytes are highly specialized epithelial cells ...

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