MedEspera 2024: Recent submissions

  • GLUTs genetic defects as causes of diabetes 
    Ciuchitu, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes mellitus (DM) is a chronic disease marked by insulin secretion or action defects. The cause of diabetes can be genetic defects of glucose transporters – GLUT, the most characteristic being the GLUT2 ...
  • Porto-systemic venous shunts 
    Smerea, Viorel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Portosystemic shunts are abnormal vessels that allow portal blood to enter the systemic circulation without passing through the liver. They can be extrahepatic, where the vascular abnormalities are outside ...
  • Bioethical aspects of the rehabilitation of patients with type 2 diabetes in conditions of anti-pandemic restrictions 
    Croitoru, Vera (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rehabilitation is essential for many health conditions such as acute stroke, cardiac events and endocrine diseases and others. It is estimated that due to the SARS COV-2 pandemic, an estimated range of 1.3–2.2 ...
  • The significant impact of artificial intelligence in TAVI 
    Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, TAVI represents a benchmark in the treatment of patients with severe aortic stenosis, becoming a durable and preferred option compared to the traditional SAVR method. The success of TAVI significantly ...
  • The involvement of micro-RNAs in cardiovascular pathologies 
    Bairamculov, Azamat (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Micro-RNAs are short molecules of ribonucleic acid with significant regulatory functions in controlling gene expression within eukaryotic cells. These small molecules play a crucial role in post-transcriptional ...
  • Nonalcoholic fatty liver disease pathogenic mechanisms and non-invasive diagnosis 
    Uncu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-alcoholic fatty liver disease (NAFLD) affects a quarter of the world's population and is one of the most common liver diseases. It can progress to liver cirrhosis and hepatocellular carcinoma (HCC). ...
  • Clinical characteristic of adults hospitalized with COVID-19 in the Republic of Moldova 
    Ciobanu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The global impact of the unprecedented COVID-19 pandemic has prompted an urgent need to comprehensively understand the clinical characteristics of affected individuals for effective healthcare management. ...
  • The role of JAK-inhibitors in the treatment of rheumatoid arthritis 
    Cozma, Octavian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis is a systemic chronic autoimmune inflammatory disease characterized by persistent destructive synovitis with extra-articular manifestations. Despite the recent development and recommended ...
  • Study of risk factors in patients with aortic stenosis 
    Vlad, Ariana; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention. With increased life expectancy and aging of the population, aortic stenosis is now one of the ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
  • Obesity: particular complications in pregnant women 
    Sofonov, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a nosological entity determined by the body's psychosomatic imbalance, resulting in energy excess and pathological expansion of adipose tissue causing severe complications and increased overall ...
  • Impact of chronic obstructive pulmonary disease on quality of life 
    Lupu, Liliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Obstructive Pulmonary Disease (COPD) is the leading cause of morbidity and mortality worldwide. According to the World Health Organization, globally, COPD is the third leading cause of death, accounting ...
  • Pulmonary tuberculosis with pneumonia-like onset in post-pandemic era: case series 
    Potop-Rotari, Dorina; Amoașii, Anastasia; Hapun, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Outbreak of pulmonary tuberculosis (TB) in post-COVID-19 era represents a real medical and social problem. It remains a diagnostic challenge due to a variety of respiratory (pneumonia, malignancy etc.) and ...
  • The influence of obesity on the quality of life in patients with gastro-esophageal reflux disease 
    Stoica, Mihaela; Munteanu, Ecaterina; Neagu, Stepan; Sârbu, Oxana; Calin, Ghenadie; Scurtu, Alina; Scorpan, Anatolie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity or exaggerated growth of adipose tissue according to body mass index (BMI) has shown an increase in the prevalence of gastroesophageal reflux disease (GERD), which significantly affects the quality ...
  • Hypereosinophilic syndrome - diagnostic challenges in allergic patients 
    Chiosa, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Eosinophilia is a common laboratory manifestation associated with multiple diseases (allergic, parasitic, infectious or oncological diseases). Eosinophilia is an increase in the absolute values of eosinophils ...
  • Post-COVID-19 sequelae 
    Focsa, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. COVID-19 is a pandemic infection caused by the novel severe acute respiratory syndrome coronavirus-2, affecting millions of people worldwide and having devastating consequences on health systems, the economy, ...
  • Chronic obstructive pulmonary disease and depression 
    Avadănii, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
  • Diagnostic accuracy of Xpert Ultra for microbiological confirmation of pulmonary tuberculosis in patients with paucibacillary disease 
    Sîrbu, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Worldwide, up to one-third of pulmonary tuberculosis patients are missed for microbiological confirmation. Assessment of specimens obtained during bronchoscopy is one of the well-recognized methods that can ...
  • Laboratory markers in the diagnosis of hereditary gluten intolerance 
    Rotari, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...
  • Consequences of pulmonary hypertension and rightsided heart failure 
    Ursu, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pulmonary hypertension (PH) is common in several pathologies and maintains high levels of morbidity and mortality. In PH the main consequence is right heart failure, which leads to complex clinical syndrome ...

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