MedEspera 2024: Recent submissions

  • Combined administration of docetaxel and apigenin inhibits breast cancer cell survival and migration 
    Nizamudeen, Fathima (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Breast cancer, an urgent global health issue, necessitates innovative therapeutic approaches. This study focuses on HER2-positive breast cancer characterized by overexpression of the HER2 gene. Apigenin, a ...
  • Etiology and diagnostic particulars of benign ovarian tumors 
    Ambrosiv, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the official data, the most widespread diseases of the reproductive system, at women of reproductive age, are ovarian tumors. The research results address the etiology and diagnosis of benign ...
  • Histological and immunohistochemical particularity of pectoralis gland cancer. Retrospective study in Oncology Institute from Moldova (2017-2022) 
    Ameena, Jasmin Rahman Nareekode Paramba Mujeeb Rahman (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pectoral Gland cancer in men is rare and occurs in 0.5-1% of all breast cancers. The risk factors are various, but the most common are the genetic mutation of BRCA2, familial history, and hormone disbalance. ...
  • The role of predictive factors of hemorrhagic transformation in patients with ischemic stroke undergoing intravenous thrombolysis 
    Frimu, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intravenous thrombolysis (IT) is the standard intervention for patients with ischemic stroke that demonstrates a significant rate of reduction in mortality and disability. Hemorrhagic transformation (HT) after ...
  • The role of 3D-printing technologies in oncology - a comprehensive study among medical students 
    Valic, Eugeniu; Valic, Vladimir (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The 3D-printing technologies (3D-PT) are considered as a game-changing way of manufacturing a variety of objects and products with a computer-guided precision. They are used nowadays in various domains, ...
  • Male breast cancer: epidemiology and risk factors 
    Saini, Jai (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Although the prevalence of breast cancer is significantly lower in men than in women, understanding the unique epidemiology and associated risk factors of breast cancer is of paramount importance. This study ...
  • Navigating the challenges of short Bowel syndrome 
    Cucu, Alexandra-Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Short bowel syndrome (SBS) is a rare condition characterized by malabsorption of macronutrients, micronutrients, electrolytes, and water following extensive resection or loss of a significant portion of the ...
  • Study of the chemotherapy treatment of patients with malignant melanoma with distant metastases during the years 2018-2022 within the IMSPIO of the Republic of Moldova 
    Miaun, Cătlin-Cătălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malignant melanoma is one of the most aggressive malignant tumors in the world, and the incidence and mortality increase annually due to the multitude of risk factors and insufficient information among the ...
  • Malignant tumors in children: epidemiological and evolutionary aspects 
    Rusu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The spectrum of malignant tumors in children differs significantly from that of adults. Whereas adult tumors are the result of cell differentiation from a mature tissue histologically, pediatric tumors originate ...
  • Surgical treatment of cutaneous malignant melanoma 
    Pușcaș, Nina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cutaneous malignant melanoma (MMC) represents a current problem of clinical oncology, the cause being its biological particularities, aggressive evolution and early metastasis. The actuality is determined by ...
  • The occurrence of venous thromboembolism at patients undergoing neoadjuvant chemotherapy 
    Rotaru, Dan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Venous thromboembolism (VTE) is a common complication in cancer patients receiving adjuvant treatment, but its prevalence during neoadjuvant chemo-radiotherapy remains uncertain. Aim of study. This systematic ...
  • The essence of the biopsychosocial model in medical rehabilitation 
    Ojovan, Vitalina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The biopsychosocial model is an approach that establishes the existence of multiple factors that influence a person's development and well-being in the context of a disease, disorder, or disability. There are ...
  • Role of neoadjuvant chemotherapy in locally advanced gastric cancer 
    Cazacu, Oleg (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Locally advanced gastric cancer (LAGC) remains a very aggressive condition, being the 5th most common malignant tumor worldwide and the 4th leading cause of death, surgical intervention remaining as the main ...
  • Treatment and rehabilitation of children with congenital, uveal and traumatic cataracts 
    Lopotencu, Francesca (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cataract among children is one of the major causes of preventable childhood blindness, affecting approximately 200,000 children worldwide, with an estimated prevalence ranging from 3 to 6 per 10,000 new-borns. ...
  • Impact of oxidative stress on lens proteins 
    Marciuc Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The impact of oxidative stress (OS) on lens proteins is a crucial aspect of ocular health, as the lens plays an essential role in visual function. The intricate interplay between oxidative stressors and lens ...
  • Benign tumors of the vocal cords. General notions. Epidemiology, etiopathogenesis and treatment 
    Țîbulac, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Benign vocal lesions are non-malignant growths of abnormal tissue on the vocal cords. The common benign lesions of vocal cord are singer’s nodule, polyps, papilloma, polypoid degeneration (Reinke’s edema) and ...
  • Heterochromia: causes, risk factors, treatment 
    Aramă, Crina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the National Center for Biotechnology Information, approximately 1% of the global population is diagnosed with heterochromia. Iris heterochromia is the uneven pigmentation of the iris, either ...
  • Evolutionary methods to identify the ocular lymphatic 1,61 1,61 system 
    Ciorba, Nadejda (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Compared to blood vessels, lymphatics can be identified much harder in the human body, especially at the eye level. Lymphatics very often present an irregular, collapsed structure, which creates difficulty ...
  • Modern approaches to glaucoma surgical treatment 
    Omer, Levy (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Primary open-angle glaucoma, the leading cause of irreversible blindness globally, affects over 3% of people over 40 and is expected to exceed 111 million cases by 2040. Traditional management methods include ...
  • Dry eye syndrome among young people: implications, risk factors and perspectives 
    Vlas, Daria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Dry eye syndrome (DES) has become a major problem among young people, being associated with prolonged exposure to digital screens and psychological stress. Increased prevalence and impact on eye health have ...

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