MedEspera 2024: Recent submissions

  • Hemostasis disorders in cardiovascular pathologies and circulatory markers 
    Păvăleanu, Iulian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hemostasis as an important compartment of general homeostasis plays a crucial role in regulation of blood fluidity and vascular wall defect closing and recovery. However, hemostasis disorders accompanied with ...
  • Iron metabolism aspects: malabsorption, transport and storage related diseases 
    Rimbu, Damiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron Deficiency Anemia (IDA), the main Iron deficiency-based disorder, is one of the leading global health problems, affecting 22,8% (2019) of the population, the most exposed groups being rapidly growing ...
  • The morphopathological aspect of metabolicassociated fatty liver disease 
    Trocin, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Being proposed in 2020, the novel terminology for Metabolic-Associated Fatty Liver Disease (MAFLD) involves the strong association of fatty liver disease with metabolic factors rather than NAFLD, the term ...
  • The role of cardiac fibrosis in diastolic heart dysfunction 
    Semionov, Marius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiac diastolic dysfunction (DD) represents globally one of the main causes for congestive cardiac failure, occurring in 1/3 of reported cases. DD is most commonly a consequence of systemic arterial ...
  • Pathogenesis of sexual dysfunction 
    Azar, Fadi (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. This text discusses the prevalence and impact of sexual dysfunction, including issues like erectile dysfunction, orgasmic disorders, delayed ejaculation, premature ejaculation, and sexual pain disorders. Aim ...
  • Morphopathology significance in detection and differential diagnosis of gastritis 
    Stoica, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The term Gastritis in morphopathology is used to describe the inflammation of gastric mucosa. Ordinarily gastritis is associated with Helicobacter Pylori which is positive in 85 % of patients, other cases of ...
  • Mesenchymal stem cell-derived exosomes and their antineoplastic potential 
    Louka, George (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stem cells (MSC) are pluripotent cell types derived from mesenchyme able to differentiate and proliferate into a variety of tissues. Exosomes derived from MSC exhibit a round morphology (40-160 ...
  • New concepts of treatment of carpal tunnel syndrome 
    Lungu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Carpal tunnel syndrome is the most common form of focal peripheral compressive mononeuropathy of the median nerve accompanied by pain, paresthesia, weakness along the nerve's path and represents approximately ...
  • Pharmacological approach to Wernicke-Korsakoff syndrome 
    Cernov, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wernicke-Korsakoff Syndrome (WKS) represents, in 16-38% of cases, a clinical triad of confusion, ataxia and nystagmus. Conceptualized as two distinct syndromes, 85% of survivors of the untreated acute phase ...
  • Particularities of the action of the inhibitors of the renin-angiotensin-aldosterone system in men and women 
    Nicolenco, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The renin-angiotensin-aldosterone system (RAAS) plays a significant role in cardiovascular pathology, including arterial hypertension (HTA). It has been demonstrated that endogenous sex hormones interact ...
  • Morphological and immunohistochemical features in the differential diagnosis of hydatiform mole 
    Rusnac, Ioana Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hydatidiform mole is a pathological pregnancy that belongs to the gestational trophoblastic diseases group. During histomorphological lesion examination, differentiating between molar and non-molar lesions ...
  • How to better learn hypertensive disorders of pregnancy through simulation in Republic of Moldova 
    Budianu, Cătălina; Grajdean, Elena; Manic, Milena; Coșpormac, Mihaela; Cemortan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of hypertensive disorders of pregnancy (HDP) has been reported up to 5-9%, with a significant rate of subsequent preeclampsia (15%), eclampsia (2%), and a high rate of maternal /fetal mortality ...
  • Role of fibroblasts and other non-fibroblastic stromal cells in sustaining the thyroid gland structure 
    Berbeci, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The thyroid gland is one of the most important endocrine organs that is responsible for producing hormones that regulate metabolism, growth, and development. Giving the primordial function of thyroid gland ...
  • Some aspects of optimization geriatric pharmacotherapy 
    Silnic, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. One of the main tasks of the modern health system is ensuring an adequate quality of life for the elderly, whose share in the world is constantly increasing. At the same time, the changes associated with ...
  • Evaluation of phenolic compounds in ethanolic extract of Cichorium intybus L. by HPLC method 
    Ciorba, Alina; Cojocaru-Toma, Maria; Uncu, Livia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cichorium intybus L (Chicory), of the Asteraceae family, is a perennial herbaceous plant with a long tradition of use and various pharmacological activity such as: antibacterial, antiinflammatory, analgesic, ...
  • Phytochemical analysis of Hyssopus officinalis L. from Republic of Moldova 
    Lupușor, Tatiana; Benea, Anna (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. H. officinalis wildly grows in southern Europe, Central Asia, Russia and Iran. This species is one of the important medicinal plants and is extensively cultivated in Spain, France and Italy. The aerial ...
  • Substance use disorder in individuals with schizophrenia 
    Bivol, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Schizophrenia can be defined as a mental disorder that affects a person’s thoughts, actions, expression of the emotions, perception of reality, and relations with other people. Schizophrenia is one of the ...
  • Virtual reality in psychiatry 
    Stitiuc, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Virtual reality (VR) is a computer simulation, a collection of images and sounds that form a real place or situation with which a person can interact using special electronic equipment. It allows to create ...
  • Risk factors for vascular dementia 
    Toporeț, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Vascular dementia is a neurodegenerative disorder that occurs due to cerebrovascular disease and hypoperfusion. This can range from large vessel stroke to microvascular disease. The symptoms and presentation ...
  • Video games in psychosocial rehabilitation for schizophrenia patients 
    Covalenco, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Schizophrenia is a lifelong and vigorously disabling condition, described by mental decline, positive and negative symptoms. While antipsychotic drugs and psycho-social interventions have shown efficacy in ...

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