MedEspera 2024: Recent submissions

  • The biochemical relationship between stress and autoimmunity 
    Buciumaș, Aurelia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Stress is a state of concern or psychological tension which appears because of a difficult situation. Stress is a normal response of our body that helps us survive all the challenges and threats of our ...
  • Genetic factors responsible for ovarian reserve 
    Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
  • The cardiotoxicity of local anesthetics 
    Talasimov, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
  • Diagnosis and treatment: insights on a clinical case of visceral sarcoidosis 
    Benchebchoub, Ouassim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sarcoidosis is a systemic disease involving formation of granulomas that can affect the lungs, skin or lymph nodes, and less commonly the eyes, heart, liver and brain, though any organ can be affected. The ...
  • Challenges and opportunities of the artificial intelligence in respiratory medicine 
    Stafi, Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Artificial Intelligence is a mechanism capable of actively perceiving the surrounding environment, taking initiatives to maximize the chances of successfully achieving its objectives. Additionally, it can ...
  • Wheat-dependent exercise-induced anaphylaxis 
    Cebotari, Iuliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a rare food allergy that can lead to severe anaphylactic reactions. The reactions usually occur 1–4 hours after consuming wheat, followed by physical ...
  • Strategies and approaches adopted by community nurses from the Republic of Moldova in promoting a healthy lifestyle 
    Chitoroagă, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Community nurses play a vital role in promoting the health and well-being of the population, particularly in adopting and maintaining a healthy lifestyle. In the Republic of Moldova, these medical professionals ...
  • Indications and limits of gene therapy 
    Doni, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gene therapies represent advanced medical tools that aim to fix or improve genes by correcting mutations or making modifications at a specific site. While there are several successful protocols, it remains a ...
  • Hyperferritinemia in liver diseases - diagnosis and controversies 
    Faraj, Shehab (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ferritin is a protein that plays a crucial role in iron storage and regulation within the body. It is found primarily within cells, particularly in the liver, spleen, bone marrow, and other tissues that store ...
  • Particular features of rheumatoid arthritis onset in the elderly 
    Curilov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic inflammatory disease that can occur at any age, but it can manifest differently in different decades of age. Obvious and significant manifestations of RA occur in those ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Herpes zoster in patients with HIV/AIDS. Epidemiological, clinical and treatment features 
    Josan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Herpes Zoster represents the phenotype, conditioned by the reactivation of the Varicella zoster virus from its latent phase. It manifests itself as viral ganglioneuritis with damage to the intervertebral ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • RpoB S450L mutation and transmission features of MDR mycobacterium tuberculosis strains in the Republic of Moldova. 
    Chesov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Republic of Moldova (RM) faces a significant challenge with a high prevalence of multidrug-resistant tuberculosis (MDR-TB). Aim of study. This study aims to explore the potential impact of rpoB S450L ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • The significant impact of artificial intelligence in TAVI 
    Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, TAVI represents a benchmark in the treatment of patients with severe aortic stenosis, becoming a durable and preferred option compared to the traditional SAVR method. The success of TAVI significantly ...
  • Interplay of glucose metabolism and its influence on myopia development 
    Dacu, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Available data suggests that by the year 2050, approximately half of the global population will experience nearsightedness, marking myopia as a genuine worldwide epidemic. To this day, the impact of nutrition ...
  • Study of risk factors in patients with aortic stenosis 
    Vlad, Ariana; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention. With increased life expectancy and aging of the population, aortic stenosis is now one of the ...
  • The impact of COVID-19 on patients with non-Hodgkin lymphoma 
    Dediu, Luminița (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Patients diagnosed with coronavirus 2019 (COVID-19) disease during hematological malignancies have been described as having a poor outcome, with only a few reports specifically addressing patients with lymphoma. ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...

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