MedEspera 2024: Recent submissions

  • Biochemical changes of the vascular endothelium in diabetic pathology 
    Stici, Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes mellitus (DM) is a multifactorial pathology that has become a worldwide problem due to its rapid spread and progression. Persistent hyperglycemia in DM induces disruption of vascular homeostasis by ...
  • Autoimmune polyglandular syndrome type 2: a case report 
    Surguci, Doina; Dumbrăveanu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Autoimmune polyglandular syndromes are classified into two major subtypes, each characterized by involvement of specific endocrine glands. The autoimmune polyglandular syndrome type 2 is defined by the presence ...
  • The role of leptin in the pathogenesis of metabolic dysfunction-associated fatty liver disease 
    Darii, Felicia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Metabolic dysfunction-associated fatty liver disease (MAFLD) has become one of the leading causes of end-stage liver disease. Its pathogenesis is not fully understood, but leptin may contribute to the development ...
  • Psycho-emotional state before and after the injectable procedure 
    Cazacu, Victoria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Persons who would like a change of the exterior, including those who are often afraid to start the aesthetic intervention for reasons when they want to stop the procedure, will look worse or are afraid of the ...
  • Disruption of the immune response in patients with obesity during COVID-19 
    Zahlîstnîi, Bogdan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity was one of the frequent comorbidities in hospitalized patients with SARSCoV-2 infection. The recent studies of Covid-19 outcomes have noticed a correlation between obesity and more severe clinical ...
  • GLUTs genetic defects as causes of diabetes 
    Ciuchitu, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes mellitus (DM) is a chronic disease marked by insulin secretion or action defects. The cause of diabetes can be genetic defects of glucose transporters – GLUT, the most characteristic being the GLUT2 ...
  • Recurrent hypoglycemia in patients with diabetes and liver cirrhosis – a real therapeutic challenge 
    Sîrbu, Felicia; Vieru, Daniela; Gușanu, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes is a global health problem, currently about 540 million adults suffer from diabetes, according to data published by the International Diabetes Federation. Approximately 20-60% of patients with cirrhosis ...
  • Clinical characteristics of children hospitalized with covid 19 in the Republic of Moldova 
    Babilev, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The World Health Organization named 2019 the year of global emergency. The disease that left its mark on humanity caused by the SARS-CoV-2 virus was called COVID-19. In the Republic of Moldova, 5.1% of the ...
  • Interplay of glucose metabolism and its influence on myopia development 
    Dacu, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Available data suggests that by the year 2050, approximately half of the global population will experience nearsightedness, marking myopia as a genuine worldwide epidemic. To this day, the impact of nutrition ...
  • Unlocking the shield: examining retinal protection via macular carotenoids' antioxidant capacity 
    Buraga, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The human retina, crucial for vision, is highly susceptible to oxidative damage due to its exposure to light and high metabolic activity. Three macular xanthophylls (MXs) – zeaxanthin (Z), lutein (L), and ...
  • Clinical manifestations and complications of acromegaly 
    Doicov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acromegaly is a rare disease that requires a specific approach in evaluating clinical symptoms and complications. Aim of study. Evaluation of clinical manifestations, onset and complications of acromegaly for ...
  • The biochemical relationship between stress and autoimmunity 
    Buciumaș, Aurelia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Stress is a state of concern or psychological tension which appears because of a difficult situation. Stress is a normal response of our body that helps us survive all the challenges and threats of our ...
  • Genetic factors responsible for ovarian reserve 
    Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
  • The cardiotoxicity of local anesthetics 
    Talasimov Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
  • Diagnosis and treatment: insights on a clinical case of visceral sarcoidosis 
    Benchebchoub, Ouassim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sarcoidosis is a systemic disease involving formation of granulomas that can affect the lungs, skin or lymph nodes, and less commonly the eyes, heart, liver and brain, though any organ can be affected. The ...
  • Molecular aspects of aminoglycoside ototoxicity 
    Cojevnicov, Emanuela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aminoglycosides are a class of antibiotics widely used in pediatric clinical practice due to their effectiveness against gram-negative bacterial infections. Despite this, they are known to have cochleotoxicity ...
  • Adenoviral infection in children: case report 
    Spînu, Tatiana; Olevschi, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Adenoviruses cause acute respiratory infections, clinically characterized by symptoms such as fever, intoxication, and a range of extra respiratory signs, including conjunctivitis, lymphadenopathy, diarrhea, ...
  • Particular features of rheumatoid arthritis onset in the elderly 
    Curilov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic inflammatory disease that can occur at any age, but it can manifest differently in different decades of age. Obvious and significant manifestations of RA occur in those ...
  • Cerebral venous thrombosis after total knee arthroplasty: clinical case report 
    Malai. Sergiu; Dumitrasco, Ana-Maria; Todica, Vlad (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cerebral venous thrombosis (CVT) represents a rare subtype of stroke involving cerebral veins and sinuses, characterized by challenging diagnosis due to its atypical clinical presentations and low occurrence. ...
  • Imagistic methods in supratentorial cerebral tumors prolong the survival among adult patients 
    Dumitrașco, Ana-Maria; Croitoru, Dan; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Supratentorial cerebral tumors are life-threatening conditions and may lead to a variable survivability among adult patients. It was proven that the complexity of the imagistic methods along with neuronavigation ...

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