MedEspera 2024: Recent submissions

  • Immunological peculiarities and the specifics of the use of therapeutic ozone in women with the risk of infertility 
    Zagorneanu, Cezar; Petrov, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. A quite specific problem regarding sexual and reproductive health that nowadays’ society is facing is represented by infertility amongst young women. This condition can be caused by a myriad of pathologies, ...
  • Circadian rhythm disturbances and immune system 
    Hagag, Lee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intricate dance between the immune system (IS) and circadian rhythm (CR) orchestrates a finely tuned symphony within the human body. IS is the body's vigilant defender against pathogens, relying on ...
  • The histological miracle of the circulatory system 
    Ustroi, Liudmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The cardiovascular or circulatory system is designed to ensure the survival of all cells in the body at all times and does this by maintaining the immediate chemical environment of each cell in the body at a ...
  • Hyssopus officinalis L. the source of diosmin as the therapeutic agent in different diseases 
    Golub, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The species Hyssopus officinalis L. is known over the years as a medicinal plant based on volatile oils. In the last 3 decades, scientific researchers have highlighted different classes of therapeutically ...
  • Study of medications designed for urethral administration 
    Adam, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, worldwide, according to studies, approximately 60% of women and 20% of men declare a urinary problem throughout their lives, such as: urethritis, cystitis, prostatitis, etc. Thus, for a complex ...
  • Anatomical variants of the median sacral artery 
    Rotaraș, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Knowing the anatomical variants of the median sacral artery has the applied significance, since it is necessary for the surgeons when choosing the operational techniques, in order to ensure the safe access ...
  • Corpus callosum agenesis in morphoclinical aspect 
    Rotaraș, Arina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Agenesis of the corpus callosum (ACC) is a congenital brain anomaly, characterized by the absence of commissural fibers connecting the two large hemispheres of the brain. This can be partial or total and can ...
  • Treatment of generalized nodal non-Hodgkin's lymphomas 
    Dunas, Adriana; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-Hodgkin's lymphomas (NHL) comprise a diverse group of malignant lymphoid tumors, with multiple distinct histological and immunohistochemical subtypes. Understanding and differentiating these subtypes is ...
  • Epidemiological and clinical aspects of indolent extranodal non-Hodgkin's lymphoma in the Republic of Moldova 
    Josanu, Marina; Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-Hodgkin's lymphoma (NHL)-lymphoproliferative tumors that are histologically and biologically heterogeneous. The most common subtypes of indolent NHL being follicular lymphoma (FL), marginal zone lymphoma ...
  • Immunohistochemical particularities as prognostic factors in diffuse large B-cell non-Hodgkin lymphoma 
    Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diffuse Large B-Cell Lymphoma (DLBCL), the most common type of NonHodgkin Lymphoma (NHL) globally, is classified into two distinct biological categories based on the gene expression profile (GEP): the germinal ...
  • Genetic aspects of migraine 
    Morari, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Migraine is a common neurological disorder which affects 15–20% of the population and usually begins at puberty, but has the greatest impact on people aged 35 to 45 years. Migraines present a severe headache ...
  • Secondary prevention of sudden cardiac death in patient with ischemic heart disease 
    Pruteanu, Albert (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sudden cardiac death (SCD) is the cause of about ½ of all cardiovascular deaths, while up to 50% is the first manifestation of heart disease. The annual incidence of SCD increases with age, so in the eighth ...
  • Treatment of Hodgkin’s lymphoma in advanced stages 
    Marandici, Daniel; Musteață, Larisa; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hodgkin's lymphoma is a relatively frequent neoplasm of the lymphatic system representing one of the most common types of cancer in young adults. Hodgkin's lymphoma is an aggressive, clinico-pathologically ...
  • The medical rehabilitation program improves the quality of life of patients with AMI 
    Badan, Maxim; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of acute myocardial infarction (AMI) is continuously increasing. In 2019, mortality from cardiovascular diseases reached 9 million people each year in Europe. Cardiovascular diseases are the ...
  • Unraveling the molecular signaling pathways in glial tumors with methylated MGMT promoters 
    Croitoru, Dan; Andronachi, Victor; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Most gliomas are typically assessed using imaging methods. A recent advancement in this regard involves the integration of biomarkers in conjunction with imaging techniques, such as 18F-FDG-PET-based radiomics ...
  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Personalized medicine and cardiovascular diseases 
    Sooltan, Abdool Rahim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There was a remarkable growth in scientific publication on personalized medicine within the past few years in the field of cardiovascular disease. In the era of personalized/precision medicine the combination ...
  • Diagnosis and treatment: insights on a clinical case of visceral sarcoidosis 
    Benchebchoub, Ouassim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sarcoidosis is a systemic disease involving formation of granulomas that can affect the lungs, skin or lymph nodes, and less commonly the eyes, heart, liver and brain, though any organ can be affected. The ...

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