MedEspera 2024: Recent submissions

  • The medical rehabilitation program improves the quality of life of patients with AMI 
    Badan, Maxim; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of acute myocardial infarction (AMI) is continuously increasing. In 2019, mortality from cardiovascular diseases reached 9 million people each year in Europe. Cardiovascular diseases are the ...
  • Unraveling the molecular signaling pathways in glial tumors with methylated MGMT promoters 
    Croitoru, Dan; Andronachi, Victor; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Most gliomas are typically assessed using imaging methods. A recent advancement in this regard involves the integration of biomarkers in conjunction with imaging techniques, such as 18F-FDG-PET-based radiomics ...
  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Cancer never takes a break — a new reality, the same relentless adversary 
    Luca, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lung cancer presents a significant global health challenge, posing a pervasive threat to individuals worldwide. It stands as a major concern, often linked to severe prognoses and a substantial impact on quality ...
  • Portal hypertension: diagnosis and treatment management 
    Toha, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Portal hypertension is responsible for the more severe and even lethal complications of chronic liver disease and cirrhosis. Aim of study. Evaluation of the effect of ozone therapy on the state of circulation ...
  • Genetic variants of COMT gene expression and influence on pain perception 
    Crasevici, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Catechol-O-methyltransferase (COMT) is a pivotal enzyme responsible for deactivating biologically active catechols, including crucial neurotransmitters such as dopamine, norepinephrine, and adrenaline. These ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Personalized medicine and cardiovascular diseases 
    Sooltan, Abdool Rahim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There was a remarkable growth in scientific publication on personalized medicine within the past few years in the field of cardiovascular disease. In the era of personalized/precision medicine the combination ...
  • External validation of a new prognostic score for mortality in the first 3 months of patients on the waiting list for liver transplantation 
    Pîrvu, Victor (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Viral liver cirrhosis is one of the most serious problems for the population due to its global spread, increased morbidity and mortality, and the high degree of disability caused by its rapid progression. Aim ...
  • Unmasking the technological innovations: insights through the encode project 
    Kuzhipurayidathil, Vijayakumar Anaswara (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Encode (Encyclopaedia of DNA Elements) Project, launched over a decade ago has played a significant role in the research world by aiding in the elucidation of the intricate human genome and its fundamental ...
  • Medical and social patterns of pelvic inflammatory disease in the Republic of Moldova 
    Căldare, Arina; Grăjdean, Victor; Vicol, Adrian; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pelvic inflammatory disease (PID) represents a significant medical and social problem. It encompasses conditions such as endometritis, salpingitis, hydrosalpinx, pyosalpinx, and tubo-ovarian abscess. The ...
  • A comprehensive approach to improving management in postpartum hemorrhage 
    Gordaș, Cătălin; Gligor. Irina; Luchianic. Vasile; Cemortan. Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity, which needs a vigilant approach for early qualified diagnosis and timely multidisciplinary management. Pregnant women at ...
  • The role of cognitive factors and respiratory dysfunction in chronic pain 
    Cuzmuc, Artiom (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In the last two decades the thorough study of cognition and breathing in the context of chronic pain have found a crucial role in the adaptation of new therapies for the management of CP ( chronic pain). The ...
  • Anosmia – a neurological complication in Covid-19 
    Markovich, Dmitry (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anosmia is a partial or complete loss of smell. It has gained great attention during COVID-19 pandemic, as many infected individuals have reported distorted sense of smell. Anosmia is a condition that can ...
  • Frequency and characteristics of common cutaneous vesiculobullous disorders in the Republic of Moldova 
    Robu, Felicia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The vesiculobullous pattern represents a large group of predominantly immunerelated disorders, morphologically characterized by blistering eruptions localized within or below the epidermis. In this study, we ...
  • Case report of a perforated intrauterine device into sigmoid colon 
    Prepeliță, Mădălina; Lavric, Irina; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intrauterine devices (IUD) have become one of the most popular birth control methods worldwide. Uterine perforation is an uncommon complication of IUD, with an incidence 1: 1,000 insertions. Perforation may ...
  • A case report of single ventricle - peculiarities of evolution in a 8-month-old child 
    Gorbatenco, Daniela; Mindru, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Single ventricle is a type of malformation when the heart has both normally developed atria, but they open into a single ventricular chamber. The disease has a multifactorial nature in which both genetic and ...
  • Transthyretin cardiac amyloidosis and bone scintigraphy: state of the art detection in rare diseases 
    Asavei, Letiția; Cârciumaru, Marius; Ciocoiu-Bunilă, Ioan Vlad; Gorea, Diana Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transthyretin cardiac amyloidosis (ATTR-ca) is a rare protein deposition disease characterized by the accumulation of amyloid in the myocardium altering its function. Diagnosing it has proven to be a challenge ...
  • Burden of bullying for mental health state in children and adolescents 
    Alexeev, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. School bullying constitutes a complex and alarming societal issue that negatively impacts students worldwide. The term "bullying" refers to repeated behaviors of intimidation, aggression, or verbal and physical ...

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