MedEspera 2024: Recent submissions

  • Iron metabolism aspects: malabsorption, transport and storage related diseases 
    Rimbu, Damiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron Deficiency Anemia (IDA), the main Iron deficiency-based disorder, is one of the leading global health problems, affecting 22,8% (2019) of the population, the most exposed groups being rapidly growing ...
  • Etiological, diagnostic and treatment aspects of chronic laryngitis 
    Bragari, Dan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Inflammatory processes affecting the upper respiratory tract can simultaneously exert a significant influence on the larynx and the surrounding mucosal surfaces. Inflammation in the larynx can be the direct ...
  • An in-depth investigation of synchronous multiple primary tumours (multicentric and bivalent) in the pancreas and colon 
    Cozma Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Multiple primary synchronous malignancy refers to the development of multiple cancerous growths in one or more organs, which are identified within a timeframe of 2-6 months (according to SEER-IARC/IARC). The ...
  • Coronary perfusion: regulation and mechanisms of disorders 
    Bria, Ilie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Coronary perfusion is a complex phenomenon ensuring the myocardial supply with oxygen and nutrients which is dependent on 2 major factors, such as myocardial compliance and feasibility of coronary arteries ...
  • Empty nose syndrome 
    Axenti, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Empty nose syndrome (ENS) is considered primarily an iatrogenic pathology, secondary to surgical treatment on the middle and lower nasal cornet. The frequency of ENS is not known exactly, several studies have ...
  • Otomycosis: symptoms, causes and treatment 
    Budu, Ana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Otomycosis is an isolated fungal infection of the external acoustic meatus. The causative strains that form biofilm inside the ear canal are mostly Aspergillus and Candida. Fungal external otitis has a worldwide ...
  • Rhinopneumometry 
    Cucerenco, Jana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rhinopneumometry is an objective method of investigating nasal function, which allows to evaluate the capacity of the nasal passages and to determine possible nasal breathing disorders. This method is widely ...
  • Advancing Parkinson's disease management: novel strategies and therapeutic innovations 
    Budianu, Cătălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parkinson's disease is a long-term neurodegenerative condition of the central nervous system that mainly affects the control of voluntary movements due to the gradual degeneration of dopaminergic neurons ...
  • TRI ponderal index as a criterion for obesity in children 
    Ajith, Aanjanay (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Childhood obesity, a global health concern linked to premature mortality, lacks a single accurate assessment method. Common anthropometric measures (weight, height, neck, abdomen, hip, arm circumferences, ...
  • Contemporary approaches to the treatment of frontotemporal dementia 
    Iarovoi, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Frontotemporal dementia or FTD relates to a group of diseases that are caused by neuronal degeneration. FTD is mainly of genetic etiology, due to mutations occurring in specific genes, and may be transmitted ...
  • Gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) 
    Bogdanov, Alan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. About 1 in 500,000 people are born with severe combined immunodeficiency (SCID). The adenosine deaminase variant is a fatal inborn error of purine metabolism. Accumulation of adenosine and deoxyadenosine ...
  • Combination of beta-blockers with ace inhibitors in the treatment of hypertension in patients with cardiac comorbidities 
    Ticlenco, Teodorina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Approximately 1.28 billion people worldwide are estimated to have hypertension, and it can either promote or accompany other cardiac comorbidities. The combination of betablockers with angiotensin-converting ...
  • Mechanisms of drug-induced nephrotoxicity 
    Iapara, Olga (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Drug-induced nephrotoxicity or drug-induced renal disease (DRID) is a common clinical problem. It has been reported that the incidence of drug-induced renal disease in adults can range from 14-26% to 66% ...
  • Drugs of choice in hypertensive emergency associated with acute aortic dissection 
    Prijilevschi, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute aortic dissection is a hypertensive emergency that requires an immediate reduction of blood pressure (BP) by administering intravenous drug therapy. Diligent control of BP is the most crucial in order ...
  • Acute drug intoxication - a modern look at old problem 
    Zveaghintev, Piotr (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute drug intoxication is a persistent and critical problem in the modern healthcare landscape. Study of the problem in recent years has marked an increase in the incidence of acute poisoning. Given the ...
  • Dapagliflozin as an SGLT2 inhibitor and its effect on the treatment of type 2 diabetes 
    Minchevici, Delia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sodium-glucose cotransporter 2 (SGLT2) inhibitors represent a drug class commonly used in the management of type 2 diabetes. Aim of study. Dapagliflozin demonstrated a significant decrease in the occurrence ...
  • Circadian rhythm disturbances and immune system 
    Hagag, Lee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intricate dance between the immune system (IS) and circadian rhythm (CR) orchestrates a finely tuned symphony within the human body. IS is the body's vigilant defender against pathogens, relying on ...
  • Significance of circadian rhythm for cardiac homeostasis 
    El Alamy, Hamdy (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Circadian rhythm plays a crucial role in the homeostasis of the cardiovascular system through hormonal secretion and the regulation of the nervous system's activity. Aim of study. This research aims to ...
  • The influence of circadian rhythms in the exacerbation of bronchial asthma 
    Mardari, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Asthma is an inflammatory disease of the airways, affecting 334 million people globally, of whom 44-61% are prone to developing complications during the night. One of the most important diagnostic criteria ...
  • The importance of daylight effects on the circadian rhythm and negative consequences of evening lightening of displays 
    Lungu, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Light is electromagnetic radiation with wavelengths between 400 and 700 nm visible to the human eye. Over recent years, a technological revolution has occurred in which conventional lightning has been replaced ...

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