MedEspera 2024: Recent submissions

  • Role of fibroblasts and other non-fibroblastic stromal cells in sustaining the thyroid gland structure 
    Berbeci, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The thyroid gland is one of the most important endocrine organs that is responsible for producing hormones that regulate metabolism, growth, and development. Giving the primordial function of thyroid gland ...
  • Some aspects of optimization geriatric pharmacotherapy 
    Silnic, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. One of the main tasks of the modern health system is ensuring an adequate quality of life for the elderly, whose share in the world is constantly increasing. At the same time, the changes associated with ...
  • Evaluation of phenolic compounds in ethanolic extract of Cichorium intybus L. by HPLC method 
    Ciorba, Alina; Cojocaru-Toma, Maria; Uncu, Livia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cichorium intybus L (Chicory), of the Asteraceae family, is a perennial herbaceous plant with a long tradition of use and various pharmacological activity such as: antibacterial, antiinflammatory, analgesic, ...
  • Phytochemical analysis of Hyssopus officinalis L. from Republic of Moldova 
    Lupușor, Tatiana; Benea, Anna (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. H. officinalis wildly grows in southern Europe, Central Asia, Russia and Iran. This species is one of the important medicinal plants and is extensively cultivated in Spain, France and Italy. The aerial ...
  • Anatomo clinical argumentation of reflexogenic zones 
    Zaharco, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. A reflexogenic zone can be defined as a specific region of the human body that, through stimulation or pressure, can influence or trigger responses in other parts of the organism. These can be considered true ...
  • Risk factors for pulmonary tuberculosis defined according to the drug-resistance profile 
    Savenco, Doina; Hujeirat, Shaher Mahmoud (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Tuberculosis (TB) represents a major health problem, listed among 30 countries with the highest burden of the drug-resistant tuberculosis (MDR-TB) and its prevalence is correlated with the risk factors such ...
  • Hereditary angioedema with C1 inhibitor deficiency 
    Butucel, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hereditary angioedema (HAE) is a rare autosomal dominant disease with deficiency or/and dysfunction of C1 inhibitor, caused by mutations in the C1-INH gene. HAE is characterized by potentially life-threatening ...
  • Cancer never takes a break — a new reality, the same relentless adversary 
    Luca, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lung cancer presents a significant global health challenge, posing a pervasive threat to individuals worldwide. It stands as a major concern, often linked to severe prognoses and a substantial impact on quality ...
  • Portal hypertension: diagnosis and treatment management 
    Toha, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Portal hypertension is responsible for the more severe and even lethal complications of chronic liver disease and cirrhosis. Aim of study. Evaluation of the effect of ozone therapy on the state of circulation ...
  • Impact of new classification of copd on assessment of severity 
    Gîlca, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease is a respiratory disease caused by abnormalities of the airways, alveoli, accompanied by chronic respiratory symptoms (dyspnea, cough, expectoration), characterized by a ...
  • Genetic variants of COMT gene expression and influence on pain perception 
    Crasevici, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Catechol-O-methyltransferase (COMT) is a pivotal enzyme responsible for deactivating biologically active catechols, including crucial neurotransmitters such as dopamine, norepinephrine, and adrenaline. These ...
  • Pulmonary tuberculosis with chronic evolution – clinical aspects 
    Vacarciuc, Eugenia-Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Evaluating the clinical features of TB in patients with chronic pulmonary processes and the effectiveness of the administered treatment Aim of study. Pulmonary tuberculosis (TB) is a public health problem, ...
  • External validation of a new prognostic score for mortality in the first 3 months of patients on the waiting list for liver transplantation 
    Pîrvu, Victor (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Viral liver cirrhosis is one of the most serious problems for the population due to its global spread, increased morbidity and mortality, and the high degree of disability caused by its rapid progression. Aim ...
  • The diagnostic challenge in a patient with metachronous malignancies 
    Polevoi, Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Metachronous malignancies are a rare entity in clinical practice. This case report reveals interconnection between a malignant adrenal tumor diagnosed 6 years ago and a rare central bronchial carcinoid tumor ...
  • Adenoviral infection in children: case report 
    Spînu, Tatiana; Olevschi, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Adenoviruses cause acute respiratory infections, clinically characterized by symptoms such as fever, intoxication, and a range of extra respiratory signs, including conjunctivitis, lymphadenopathy, diarrhea, ...
  • Particular features of rheumatoid arthritis onset in the elderly 
    Curilov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic inflammatory disease that can occur at any age, but it can manifest differently in different decades of age. Obvious and significant manifestations of RA occur in those ...
  • Cerebral venous thrombosis after total knee arthroplasty: clinical case report 
    Malai. Sergiu; Dumitrasco, Ana-Maria; Todica, Vlad (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cerebral venous thrombosis (CVT) represents a rare subtype of stroke involving cerebral veins and sinuses, characterized by challenging diagnosis due to its atypical clinical presentations and low occurrence. ...
  • Stress and neuronal cell death: pathogenetic mechanisms, management and treatment 
    Postolache, Danu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The nervous system is the most complex organ in the human body, as structurally – consisting of billions of neurons, as functionally – being responsible for cognition, behavior, and conscience. Therefore, the ...
  • Post-traumatic stress disorder and its influence on different brain structures 
    Colesnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Post-Traumatic Stress Disorder (PTSD) is a mental health condition that can develop after experiencing or witnessing a traumatic event. Trauma varies widely and can include combat, sexual assault, accidents, ...
  • Stroke in pregnancy and postpartum 
    Curnic, Andreea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Stroke is a medical emergency that requires urgent care and treatment. As everyone, regardless of age, gender or health, can experience this condition, pregnant women can have it as well. In addition to major ...

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