MedEspera 2024: Recent submissions

  • Cell therapy in chronic rhinosinusitis in children 
    Al Faraj, Iunis (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Rhinosinusitis is one of the most common chronic diseases worldwide, having an incidence between 1%-12% Globally and an incidence of 10.9% in Europe. CRS (Chronic Rhinosinusitis) is an underestimated ...
  • Conduct of patients with cervical pathology 
    Popa, Iulia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The cervix, essential in female reproduction, raises significant concerns regarding precancerous conditions with a significant global and local impact. In the Republic of Moldova, 600-700 women per year are ...
  • Histogenesis and specific morphological aspects of the photoreceptors 
    Iusiumbeli, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. People rely on visual cues to navigate the world around them. Vision begins with the detection of light by photoreceptors of the retina - the light sensitive cells of the eye. Photoreceptor types are defined ...
  • Congenital heart disease left-to-right shunt 
    Perumal, Kishorebisel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The congenital heart condition, known as cardiac septal defect, involves lesions in the atrial or ventricular septum, significantly impacting infant and child mortality. This malformation stems from disrupted ...
  • Evaluation of adiposity indices in pediatric rheumatological disorders 
    Cepraga, Victoria; Nedealcova, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Body Mass Index (BMI) is currently the most used indicator that assesses the nutritional status of children and adults, but it cannot fully reflect the difference between excess adipose tissue and that ...
  • Emicizumab in pediatric hemophilia a: a case study 
    Miaun, Livia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The development of inhibitors that neutralize the function of clotting factor VIII is currently the most challenging complication associated with the hemophilia A treatment. Emicizumab is a humanized bispecific ...
  • Cardiovascular damage in children with systemic lupus erythematosus 
    Muringakodan, Najmulhudha (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Juvenile Systemic Lupus Erythematosus (jSLE) is a rare autoimmune disorder affecting multiple systems in children and adolescents causing unique challenges in diagnosis and management. Cardiovascular ...
  • Microscopic and ultrastructural characteristics of keratinocytes 
    Coltuc, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Keratinocytes are the principal epidermal cells, constituting the outermost layer of the skin - the external and largest organ of the human body. Epidermal keratinocytes are highly specialized epithelial cells ...
  • Etiology, pathogenesis, diagnosis and treatment of ovarian cancer 
    Cheacir, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The 5th most common cause of death among women is caused by ovarian cancer. According to the American Cancer Society, the risk of being diagnosed with ovarian cancer throughout life for women is 1 in 78. In ...
  • Prospects for obtaining liposomes with standardized plant extract 
    Stahi, Cristina; Yaman, Abdin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent years, scientists have shown an increasing interest in incorporating biologically active compounds extracted from plants into nanoparticle delivery systems. Examples of such delivery systems include ...
  • Anti-cancer compounds in brassica vegetables 
    Ciurea, Laura (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cancer is the main cause of mortality and morbidity worldwide. According to the World Cancer Research Fund an estimated 40% of all human cancers are related to diet. Although a large variety of therapeutic ...
  • Study on clinical cases of atopic dermatitis in children 
    Iepure, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Allergic contact dermatitis (ACD) was once considered a rarity in children, but recent estimates suggest that it affects 4.4 million children in the United States alone. Currently, there is no cure, but an ...
  • Comparative analysis of the national and international legislative framework regarding the storage of medicinal products for human use 
    Golovei, Ina; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Globally, regulating and managing medicines is vital for public health. This presentation compares how the Republic of Moldova and the European Union handle the storage and preservation of medicines. It ...
  • Antibacterial activity of basil essential oil 
    Boguș, Dorin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basil essential oil has been demonstrated to possess various beneficial properties, including analgesic, anti-inflammatory, antibacterial, hepatoprotective, and immunomodulatory effects. The multifunctionality ...
  • The pharmacist's role in the management of the elderly's medication at home 
    Groian, Alexandra; Diaconu, Alina; Șchiopu, Tatiana; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pharmacists have a central role in ensuring the safety of medicines throughout the pharmaceutical care process. Providing advanced drug therapy management services in outpatient settings ensures the reduction ...
  • Action of biopharmaceutical factors on drug bioavailability 
    Andronachi, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the Food and Drug Administration (FDA), bioavailability represents the amount of active substance released from a pharmaceutical form, absorbed into the bloodstream, and reaching the site of ...
  • Drug interactions and errors in the treatment of hypertension in the elderly 
    Diaconu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hypertension is a condition in which the systolic and diastolic pressures are increased above the permissible limit. According to the European Society of Hypertension, for people without diabetes, the values ...
  • Liposome biopharmaceutic and nanoparticles in human body 
    Costea, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The use of nanotechnology in medicine, and more specifically in drug delivery, is rapidly spreading. Numerous substances are currently being researched for drug delivery and, in particular, cancer therapy. Aim ...
  • Infectious complications after caesarean delivery 
    Zuico, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cesarean delivery, also known as a C-section, is characterized by the delivery of a fetus through surgical incisions performed on both the abdominal wall (laparotomy) and the uterine wall (hysterotomy). ...
  • The impact of COVID-19 disease on platelets and coagulation 
    Vartic, Iana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Platelets are formed elements of blood that play an important role in blood clotting. As the main mediator of thrombus formation, platelets have become one of the key aspects in the study of SARS-CoV-2. ...

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