MedEspera 2024: Recent submissions

  • The pathophysiology of iron deficiency in the body, endangerment of the absorption, transport and storage of the cation. The main mechanisms 
    Gumeniuc, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron plays an important role in a multitude of physiological processes, such as the transport of oxygen from the lungs to the tissues, the release of molecular oxygen from organic compounds, favors the exchange ...
  • The role of genetic aspects in pathophysiology of cushing syndrome 
    Pascari, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cushing's syndrome is considered a rare disease with an incidence of 0.2– 0.5 million population per year, with an average age of 41 years at diagnosis and 1–2 cases per 100,000 population per year. As known, ...
  • Hemostasis disorders in cardiovascular pathologies and circulatory markers 
    Păvăleanu, Iulian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hemostasis as an important compartment of general homeostasis plays a crucial role in regulation of blood fluidity and vascular wall defect closing and recovery. However, hemostasis disorders accompanied with ...
  • Iron metabolism aspects: malabsorption, transport and storage related diseases 
    Rimbu, Damiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron Deficiency Anemia (IDA), the main Iron deficiency-based disorder, is one of the leading global health problems, affecting 22,8% (2019) of the population, the most exposed groups being rapidly growing ...
  • The morphopathological aspect of metabolicassociated fatty liver disease 
    Trocin, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Being proposed in 2020, the novel terminology for Metabolic-Associated Fatty Liver Disease (MAFLD) involves the strong association of fatty liver disease with metabolic factors rather than NAFLD, the term ...
  • The role of cardiac fibrosis in diastolic heart dysfunction 
    Semionov, Marius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiac diastolic dysfunction (DD) represents globally one of the main causes for congestive cardiac failure, occurring in 1/3 of reported cases. DD is most commonly a consequence of systemic arterial ...
  • Pathogenesis of sexual dysfunction 
    Azar, Fadi (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. This text discusses the prevalence and impact of sexual dysfunction, including issues like erectile dysfunction, orgasmic disorders, delayed ejaculation, premature ejaculation, and sexual pain disorders. Aim ...
  • Morphopathology significance in detection and differential diagnosis of gastritis 
    Stoica, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The term Gastritis in morphopathology is used to describe the inflammation of gastric mucosa. Ordinarily gastritis is associated with Helicobacter Pylori which is positive in 85 % of patients, other cases of ...
  • From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 
    Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
  • Immunohistochemical particularities as prognostic factors in diffuse large B-cell non-Hodgkin lymphoma 
    Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diffuse Large B-Cell Lymphoma (DLBCL), the most common type of NonHodgkin Lymphoma (NHL) globally, is classified into two distinct biological categories based on the gene expression profile (GEP): the germinal ...
  • Treatment of Hodgkin’s lymphoma in advanced stages 
    Marandici, Daniel; Musteață, Larisa; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hodgkin's lymphoma is a relatively frequent neoplasm of the lymphatic system representing one of the most common types of cancer in young adults. Hodgkin's lymphoma is an aggressive, clinico-pathologically ...
  • Congenital anomalies in newborns: syndactyly 
    Zveaghinteva, Ludmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The name of “hand” comes from the Latin “manus”, derived from “manipulus”. The hand is the most perfected segment of the human locomotor system and is a complex organ made up of 27 bones, 27 joints and 19 ...
  • Hormonal disturbances in the polycystic ovary syndrome 
    Colin, Mihai; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Polycystic ovary syndrome (PCOS) is an endocrine pathology that affects women of reproductive age. Hormonal disturbances in the PCOS are the central cause of heterogenous clinical presentation involving ...
  • Strategies and approaches adopted by community nurses from the Republic of Moldova in promoting a healthy lifestyle 
    Chitoroagă, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Community nurses play a vital role in promoting the health and well-being of the population, particularly in adopting and maintaining a healthy lifestyle. In the Republic of Moldova, these medical professionals ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • RpoB S450L mutation and transmission features of MDR mycobacterium tuberculosis strains in the Republic of Moldova. 
    Chesov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Republic of Moldova (RM) faces a significant challenge with a high prevalence of multidrug-resistant tuberculosis (MDR-TB). Aim of study. This study aims to explore the potential impact of rpoB S450L ...
  • Bullous pemphigoid, clinical aspects and treatment 
    Caradjova, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bullous pemphigoid is a chronic, potentially fatal autoimmune skin disease that results in generalized pruritic bullous eruptions in older patients. Local and systemic glucocorticosteroid drugs are prescribed ...
  • Diagnostic challenges in unusual gynecological synchronous tumor: a pathologist’s perspective 
    Ciobanu, Miruna-Olguța; Toma, Loredana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ovarian carcinosarcoma (OCS) is an uncommon high-risk malignant biphasic neoplasm consisting of morphologically high-grade carcinomatous and sarcomatous tissue elements. OCS has an incidence of 2.5% (4 cases ...
  • Chronic suppurative otitis media complicated with facial paresis 
    Iutis, Vlada; Didencu, Alexandru; Noroc, Iurie; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic otitis media (COM) is a recurrent infection affecting the middle ear and/or mastoid air cells, often accompanied by a perforated tympanic membrane (TM). Additionally, COM may progress to a condition ...

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