MedEspera 2024: Recent submissions

  • Endocrine changes and menstrual dysfunctions in adolescent girls with obesity 
    Solcanu, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent decades, there has been a significant increase in the obesity rate among adolescent girls. According to the specialized literature, obesity induces hormonal changes that have consequences on sexual ...
  • HPV status and associated precursor lesion in vulvar squamous cell carcinoma 
    Butnaru, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There are distinctive precursor lesions related to vulvar squamous cell carcinoma (VSCC) that are associated with high-risk human papillomavirus (HPV) type 16,18 specifically vulvar intraepithelial neoplasia ...
  • Morphological features of the umbilical artery in normal pregnancy and preeclampsia 
    Rusu, Ludmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The vascular component of the umbilical cord is represented by two umbilical arteries and one corresponding vein. The characteristic structure of the umbilical arteries makes them highly vulnerable to any ...
  • Hemorrhage in the 3 stage of labor and postpartum. Mothers health 
    Gorbanovsky, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is a major reason for maternal complications and deaths worldwide. The overall prevalence of PPH worldwide is estimated to be 6-11% of births with substantial variation across ...
  • Significance of circadian rhythm for cardiac homeostasis 
    El Alamy, Hamdy (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Circadian rhythm plays a crucial role in the homeostasis of the cardiovascular system through hormonal secretion and the regulation of the nervous system's activity. Aim of study. This research aims to ...
  • The influence of circadian rhythms in the exacerbation of bronchial asthma 
    Mardari, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Asthma is an inflammatory disease of the airways, affecting 334 million people globally, of whom 44-61% are prone to developing complications during the night. One of the most important diagnostic criteria ...
  • The importance of daylight effects on the circadian rhythm and negative consequences of evening lightening of displays 
    Lungu, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Light is electromagnetic radiation with wavelengths between 400 and 700 nm visible to the human eye. Over recent years, a technological revolution has occurred in which conventional lightning has been replaced ...
  • The importance of melatonin in the development of idiopathic scoliosis 
    Robu, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Adolescent idiopathic scoliosis is a common disease, with a 0.47–5.2% prevalence. The female-to-male ratio ranges from 1.5:1 to 3:1 and is increasing with age. Untreated scoliosis can cause muscle imbalances, ...
  • The role of dysfunctional breathing in the pain syndrome. respiratory biofeedback and other guided breathing techniques in pain treatment 
    Lefter, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic pain syndrome is a global health concern that significantly impacts patients' quality of life. It stems from various conditions, including degenerative joint diseases, neurological disorders, autoimmune ...
  • The importance of the circadian rhythm in the musculoskeletal development of children 
    Stratu, Teodora (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bone and muscle cells have the same circadian rhythm as the rest of the body's cells, with 24-hour oscillations governed by the primary clock. This review aimed to determine if there is a correlation between ...
  • Respiratory biofeedback for anxiety reduction through visualization of the chest movements 
    Gaidarlî, Loredana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anxiety causes significant distress to patients and remains one of the most common complaints in primary healthcare. Family physicians often find themselves seeking the most effective treatment for patients, ...
  • Training of abdominal breathing on purpose of reducing anxiety by restricting the chest movements 
    Muntean, Elizaveta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The respiratory biofeedback method is based on executing of paced voluntary respiratory movements in order to reeducate a dysfunctional breathing pattern into a physiologically normal one. Respiratory biofeedback ...
  • Maternal circadian rhythm and sleep disorders as a risk factor for autism spectrum disorder 
    Lugassy, Lior (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
  • Gluten intolerance. Celiac disease 
    Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
  • The influence of type 2 pregestational diabetes mellitus on the fetus 
    Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
  • The role of gut microbiota metabolites in atherosclerosis 
    Berliba, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Changes in gut microbiota metabolites(GMM) is linked to the development of CVD, which includes atherosclerosis, hypertension, ...
  • Mechanisms of action and metabolic effects of anticoagulants 
    Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
  • Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 
    Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
  • Biochemical aspects of malabsorption syndromes 
    Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
  • The anatomical variability of the last three pairs of the intercostal arteries 
    Croitoru, Dan; Coșciug, Stanislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intercostal arteries are of vital significance in the vascularisation of the intercostal musculature, fascia and the ribs. The last three pairs are involved in the blood supply of the antero-lateral ...

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