MedEspera 2024: Recent submissions

  • Drug-drug interactions among hypertensive patients 
    Boico, Irina; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hypertension has increased prevalence and concurrent comorbidities, because these patients are treated with a complex therapeutic regimen comprising multiple different drugs. A drug interaction is a reaction ...
  • Infective endocarditis caused by Staphylococcus aureus 
    Coneschi-Covalciuc, Vladislava; Ciobanu, Miruna Olguța (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Infective endocarditis (IE) is an infection of the endothelium of the heart that can occur in 1-6% of patients. The clinical presentation may present as an acute, subacute, or chronic condition reflecting the ...
  • Recurrent hypoglycemia in patients with diabetes and liver cirrhosis – a real therapeutic challenge 
    Sîrbu, Felicia; Vieru, Daniela; Gușanu, Olesea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetes is a global health problem, currently about 540 million adults suffer from diabetes, according to data published by the International Diabetes Federation. Approximately 20-60% of patients with cirrhosis ...
  • Clinical characteristics of children hospitalized with covid 19 in the Republic of Moldova 
    Babilev, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The World Health Organization named 2019 the year of global emergency. The disease that left its mark on humanity caused by the SARS-CoV-2 virus was called COVID-19. In the Republic of Moldova, 5.1% of the ...
  • Treatment of acute non-lymphoblastic leukemias 
    Pusca, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute myeloid leukemias (AML) are a group of hematological malignancies with primary involvement of the bone marrow (BM). These disorders of hematopoietic system develop due to genetic changes in blood cell ...
  • Unlocking the shield: examining retinal protection via macular carotenoids' antioxidant capacity 
    Buraga, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The human retina, crucial for vision, is highly susceptible to oxidative damage due to its exposure to light and high metabolic activity. Three macular xanthophylls (MXs) – zeaxanthin (Z), lutein (L), and ...
  • Clinical manifestations and complications of acromegaly 
    Doicov, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acromegaly is a rare disease that requires a specific approach in evaluating clinical symptoms and complications. Aim of study. Evaluation of clinical manifestations, onset and complications of acromegaly for ...
  • Clinical and hematological features and diagnostic options in extranodal aggressive non-Hodgkin's lymphomas 
    Pîrlii, Iulius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lymphomas can be simply defined as malignant neoplasms of lymphocytes and their precursor cells. Common sites of extranodal manifestations are the gastrointestinal tract, especially the ventricle, pharynx, ...
  • Genetic factors responsible for ovarian reserve 
    Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
  • The cardiotoxicity of local anesthetics 
    Talasimov, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
  • Applicability of the CLDQ in the monitoring of patients with delta viral liver cirrhosis 
    Cebanu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The clinical burden of delta viral cirrhosis is significant in terms of health, quality of life, and economic impact on patients and society. The Chronic Liver Disease Questionnaire (CLDQ) is an instrument ...
  • Stroke in pregnancy and postpartum 
    Curnic, Andreea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Stroke is a medical emergency that requires urgent care and treatment. As everyone, regardless of age, gender or health, can experience this condition, pregnant women can have it as well. In addition to major ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Herpes zoster in patients with HIV/AIDS. Epidemiological, clinical and treatment features 
    Josan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Herpes Zoster represents the phenotype, conditioned by the reactivation of the Varicella zoster virus from its latent phase. It manifests itself as viral ganglioneuritis with damage to the intervertebral ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • Diagnostic challenges in unusual gynecological synchronous tumor: a pathologist’s perspective 
    Ciobanu, Miruna-Olguța; Toma, Loredana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ovarian carcinosarcoma (OCS) is an uncommon high-risk malignant biphasic neoplasm consisting of morphologically high-grade carcinomatous and sarcomatous tissue elements. OCS has an incidence of 2.5% (4 cases ...
  • Chronic suppurative otitis media complicated with facial paresis 
    Iutis, Vlada; Didencu, Alexandru; Noroc, Iurie; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic otitis media (COM) is a recurrent infection affecting the middle ear and/or mastoid air cells, often accompanied by a perforated tympanic membrane (TM). Additionally, COM may progress to a condition ...
  • Cochlear implantation in deaf-mute adult with partial optic nerve atrophy 
    Istrati, Andriana; Noroc, Iurie; Vetricean, Sergiu; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Congenital deafness together with that acquired at a young age represent important pathological conditions, with an incidence of about 1-3 cases per 1000 live births, being diagnosed relatively late has ...
  • Cell therapy in chronic rhinosinusitis in children 
    Al Faraj, Iunis (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Rhinosinusitis is one of the most common chronic diseases worldwide, having an incidence between 1%-12% Globally and an incidence of 10.9% in Europe. CRS (Chronic Rhinosinusitis) is an underestimated ...

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