MedEspera 2024: Recent submissions

  • Contemporary approaches to the treatment of frontotemporal dementia 
    Iarovoi, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Frontotemporal dementia or FTD relates to a group of diseases that are caused by neuronal degeneration. FTD is mainly of genetic etiology, due to mutations occurring in specific genes, and may be transmitted ...
  • Combination of beta-blockers with ace inhibitors in the treatment of hypertension in patients with cardiac comorbidities 
    Ticlenco, Teodorina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Approximately 1.28 billion people worldwide are estimated to have hypertension, and it can either promote or accompany other cardiac comorbidities. The combination of betablockers with angiotensin-converting ...
  • The transcondylar fractures in children, particularities of diagnosis and treatment 
    Corcodel, Mariana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transcondylar fractures of the humerus are the most frequent fractures at the level of elbow facing children. These can be extremely difficult to manage and if the way if treatment is not correct, then ...
  • Treatment of cervical cystic lymphangioma in children 
    Mihălache, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cervical cystic lymphangioma is a malformation of the lymphatic vessels predominantly located in the cervical, head or axillary area, but can affect any region. The location of lymphangioma in the cervical ...
  • Acute drug intoxication - a modern look at old problem 
    Zveaghintev, Piotr (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute drug intoxication is a persistent and critical problem in the modern healthcare landscape. Study of the problem in recent years has marked an increase in the incidence of acute poisoning. Given the ...
  • Dapagliflozin as an SGLT2 inhibitor and its effect on the treatment of type 2 diabetes 
    Minchevici, Delia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sodium-glucose cotransporter 2 (SGLT2) inhibitors represent a drug class commonly used in the management of type 2 diabetes. Aim of study. Dapagliflozin demonstrated a significant decrease in the occurrence ...
  • Anti-cancer compounds in brassica vegetables 
    Ciurea, Laura (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cancer is the main cause of mortality and morbidity worldwide. According to the World Cancer Research Fund an estimated 40% of all human cancers are related to diet. Although a large variety of therapeutic ...
  • Use of sodium-glucose cotransporter 2 inhibitors in heart failure 
    Ferdohleb, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Heart failure syndrome has been designated as a major clinical and public health problem. Ischemic cardiopathy, arterial hypertension, cardiomyopathies, myocarditis, pericarditis valvulopathies, arrhythmias, ...
  • Three generations of β-blockers: class differences and clinical applicability 
    Lopatinschi, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction: The evolution of beta-blockers remedies has greatly influenced the management of a large scale of disorders. Research divides all beta blockers into three generations: first-generation nonselective ...
  • Tirzepatide – new treatment option for patient with type 2 diabetes 
    Mufeed, Majeed (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Type II diabetes is a global problem of the 21st century. The incidence of diabetes is increasing significantly and alarmingly over the years, thus according to WHO data the rate of diabetes has increased ...
  • Comparative analysis of the national and international legislative framework regarding the storage of medicinal products for human use 
    Golovei, Ina; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Globally, regulating and managing medicines is vital for public health. This presentation compares how the Republic of Moldova and the European Union handle the storage and preservation of medicines. It ...
  • Antibacterial activity of basil essential oil 
    Boguș, Dorin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basil essential oil has been demonstrated to possess various beneficial properties, including analgesic, anti-inflammatory, antibacterial, hepatoprotective, and immunomodulatory effects. The multifunctionality ...
  • Action of biopharmaceutical factors on drug bioavailability 
    Andronachi, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the Food and Drug Administration (FDA), bioavailability represents the amount of active substance released from a pharmaceutical form, absorbed into the bloodstream, and reaching the site of ...
  • Drug interactions and errors in the treatment of hypertension in the elderly 
    Diaconu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hypertension is a condition in which the systolic and diastolic pressures are increased above the permissible limit. According to the European Society of Hypertension, for people without diabetes, the values ...
  • Treatment of convulsive syndrome in pediatric patients 
    Bugaian, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Convulsive syndrome represents paroxysmal cerebral crises, related to excessive and hypersynchronous activity of cortical and subcortical neurons. This condition is marked by uncontrolled muscle contractions, ...
  • Immunological peculiarities and the specifics of the use of therapeutic ozone in women with the risk of infertility 
    Zagorneanu, Cezar; Petrov, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. A quite specific problem regarding sexual and reproductive health that nowadays’ society is facing is represented by infertility amongst young women. This condition can be caused by a myriad of pathologies, ...
  • Circadian rhythm disturbances and immune system 
    Hagag, Lee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intricate dance between the immune system (IS) and circadian rhythm (CR) orchestrates a finely tuned symphony within the human body. IS is the body's vigilant defender against pathogens, relying on ...
  • Significance of circadian rhythm for cardiac homeostasis 
    El Alamy, Hamdy (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Circadian rhythm plays a crucial role in the homeostasis of the cardiovascular system through hormonal secretion and the regulation of the nervous system's activity. Aim of study. This research aims to ...
  • The importance of daylight effects on the circadian rhythm and negative consequences of evening lightening of displays 
    Lungu, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Light is electromagnetic radiation with wavelengths between 400 and 700 nm visible to the human eye. Over recent years, a technological revolution has occurred in which conventional lightning has been replaced ...
  • The importance of melatonin in the development of idiopathic scoliosis 
    Robu, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Adolescent idiopathic scoliosis is a common disease, with a 0.47–5.2% prevalence. The female-to-male ratio ranges from 1.5:1 to 3:1 and is increasing with age. Untreated scoliosis can cause muscle imbalances, ...

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