MedEspera 2024: Recent submissions

  • The role of JAK-inhibitors in the treatment of rheumatoid arthritis 
    Cozma, Octavian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis is a systemic chronic autoimmune inflammatory disease characterized by persistent destructive synovitis with extra-articular manifestations. Despite the recent development and recommended ...
  • Study of risk factors in patients with aortic stenosis 
    Vlad, Ariana; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention. With increased life expectancy and aging of the population, aortic stenosis is now one of the ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
  • Hormonal disturbances in the polycystic ovary syndrome 
    Colin, Mihai; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Polycystic ovary syndrome (PCOS) is an endocrine pathology that affects women of reproductive age. Hormonal disturbances in the PCOS are the central cause of heterogenous clinical presentation involving ...
  • Obesity: particular complications in pregnant women 
    Sofonov, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a nosological entity determined by the body's psychosomatic imbalance, resulting in energy excess and pathological expansion of adipose tissue causing severe complications and increased overall ...
  • Impact of chronic obstructive pulmonary disease on quality of life 
    Lupu, Liliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Obstructive Pulmonary Disease (COPD) is the leading cause of morbidity and mortality worldwide. According to the World Health Organization, globally, COPD is the third leading cause of death, accounting ...
  • Pulmonary tuberculosis with pneumonia-like onset in post-pandemic era: case series 
    Potop-Rotari, Dorina; Amoașii, Anastasia; Hapun, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Outbreak of pulmonary tuberculosis (TB) in post-COVID-19 era represents a real medical and social problem. It remains a diagnostic challenge due to a variety of respiratory (pneumonia, malignancy etc.) and ...
  • The influence of obesity on the quality of life in patients with gastro-esophageal reflux disease 
    Stoica, Mihaela; Munteanu, Ecaterina; Neagu, Stepan; Sârbu, Oxana; Calin, Ghenadie; Scurtu, Alina; Scorpan, Anatolie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity or exaggerated growth of adipose tissue according to body mass index (BMI) has shown an increase in the prevalence of gastroesophageal reflux disease (GERD), which significantly affects the quality ...
  • Hypereosinophilic syndrome - diagnostic challenges in allergic patients 
    Chiosa, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Eosinophilia is a common laboratory manifestation associated with multiple diseases (allergic, parasitic, infectious or oncological diseases). Eosinophilia is an increase in the absolute values of eosinophils ...
  • Post-COVID-19 sequelae 
    Focsa, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. COVID-19 is a pandemic infection caused by the novel severe acute respiratory syndrome coronavirus-2, affecting millions of people worldwide and having devastating consequences on health systems, the economy, ...
  • Chronic obstructive pulmonary disease and depression 
    Avadănii, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
  • Diagnostic accuracy of Xpert Ultra for microbiological confirmation of pulmonary tuberculosis in patients with paucibacillary disease 
    Sîrbu, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Worldwide, up to one-third of pulmonary tuberculosis patients are missed for microbiological confirmation. Assessment of specimens obtained during bronchoscopy is one of the well-recognized methods that can ...
  • Laboratory markers in the diagnosis of hereditary gluten intolerance 
    Rotari, Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...
  • Consequences of pulmonary hypertension and rightsided heart failure 
    Ursu, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pulmonary hypertension (PH) is common in several pathologies and maintains high levels of morbidity and mortality. In PH the main consequence is right heart failure, which leads to complex clinical syndrome ...
  • Acute viral infection as a trigger for DSNMG: a case report 
    Stafi, Vlada; Stavila, Iulia; Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Categorical evidence shows that patients with Acute Respiratory Viral Infections have a higher risk of concurrently developing autoimmune diseases, reflecting phenotypic heterogeneity in MG. The association ...
  • Herpes zoster in patients with HIV/AIDS. Epidemiological, clinical and treatment features 
    Josan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Herpes Zoster represents the phenotype, conditioned by the reactivation of the Varicella zoster virus from its latent phase. It manifests itself as viral ganglioneuritis with damage to the intervertebral ...
  • Telomere and telomerase function: safeguarding chromosomal ends and their implications in aging and cancer development 
    Batîr, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Telomeres, the protective caps at the ends of linear chromosomes, play a crucial role in maintaining genomic stability and integrity. As cells undergo repeated divisions, telomeres progressively shorten, ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • Male breast cancer: epidemiology and risk factors 
    Saini, Jai (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Although the prevalence of breast cancer is significantly lower in men than in women, understanding the unique epidemiology and associated risk factors of breast cancer is of paramount importance. This study ...

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