MedEspera 2024: Recent submissions

  • Minimally invasive treatment of pituitary adenomas 
    Dumitrașco, Ana-Maria; Malai, Sergiu; Andrianova, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pituitary adenomas (PAs) are among the most common tumors of the central nervous system, frequently diagnosed in the third and fourth decades of life. Despite their benign classification, PAs can result in ...
  • Molecular-genetic and environmental mechanisms of myopia 
    Moldovanu, Mirela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Myopia is a multifactorial pathology that causes the decrease or loss of vision, in most cases the elongation of the longitudinal axis of the eyeball is involved. From an etiological point of view, numerous ...
  • Expression of the inflammatory syndrome manifestations in patients with seronegative rheumatoid arthritis 
    Utocichina, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA), a systemic autoimmune disease that is predominantly affecting synovial joints through a progressive destructive process, is classified into 2 subgroups - seronegative (SNRA) and ...
  • Meningococcal infection: clinical-evolutionary particularities 
    Caramalac, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Meningococcal infection is an acute infectious disease caused by meningococcus, occurring with a variety of clinical manifestations - from asymptomatic carriage and nasopharyngitis to generalized forms (purulent ...
  • The bone in the elderly 
    Trofimov Cristian; Mazur-Nicorici Lucia; Stratulat Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bone remodeling is a complex phenomenon regulated by bone cells and enzymes implicated in bone metabolism. Aim of study. The aim of the study was to describe the processes involved in bone remodeling during ...
  • Basal cell carcinoma, clinical aspects 
    Rachieru, Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basal cell carcinoma (BCC) is a non-melanocytic skin cancer that originates from the basal cells of the epidermis. This condition is characterized by a continuously increasing incidence, attributed to the ...
  • Depression after cerebral vascular accident: frequency, risk factors and impact on quality of life 
    Timuș, Roman; Gavriluța, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Post-stroke depression is one of the most common complications, affecting about one third from the survivors after a stroke. In combination with cognitive aggravation, post-stroke depression slows down the ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • RpoB S450L mutation and transmission features of MDR mycobacterium tuberculosis strains in the Republic of Moldova. 
    Chesov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Republic of Moldova (RM) faces a significant challenge with a high prevalence of multidrug-resistant tuberculosis (MDR-TB). Aim of study. This study aims to explore the potential impact of rpoB S450L ...
  • Bullous pemphigoid, clinical aspects and treatment 
    Caradjova, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bullous pemphigoid is a chronic, potentially fatal autoimmune skin disease that results in generalized pruritic bullous eruptions in older patients. Local and systemic glucocorticosteroid drugs are prescribed ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • Unmasking the technological innovations: insights through the encode project 
    Kuzhipurayidathil, Vijayakumar Anaswara (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Encode (Encyclopaedia of DNA Elements) Project, launched over a decade ago has played a significant role in the research world by aiding in the elucidation of the intricate human genome and its fundamental ...
  • What do students know about sexually transmitted diseases and methods of contraception? A survey study about knowledge and sexual risk behaviours among university students 
    Jurca, Denisa-Amalia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sexual life is of considerable importance, particularly in youngsters, not only because of its Sexual life is extremely important, especially for young people, not just because it affects intellectual development ...
  • Anomalous 12mm melanoma 
    Tomuț, Alexandru-Nicușor (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Despite its relatively low frequency, melanoma is considered the most hazardous form of skin cancer. It manifests as a developmental atypia of melanocytes, cells derived from the neural crest. Frequent sites ...
  • Bone scintigraphy - the coner stone in treatment management for osteophilic neoplasms 
    Gorea, Diana Valentina; Asavei, Letitia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bone scintigraphy is a nuclear medicine imaging investigation that studies the biodistribution of a radiotracer at the skeletal level. It is considered to be a very sensitive technique due to the fact that ...
  • Frequency and characteristics of common cutaneous vesiculobullous disorders in the Republic of Moldova 
    Robu, Felicia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The vesiculobullous pattern represents a large group of predominantly immunerelated disorders, morphologically characterized by blistering eruptions localized within or below the epidermis. In this study, we ...
  • Diagnostic challenges in unusual gynecological synchronous tumor: a pathologist’s perspective 
    Ciobanu, Miruna-Olguța; Toma, Loredana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ovarian carcinosarcoma (OCS) is an uncommon high-risk malignant biphasic neoplasm consisting of morphologically high-grade carcinomatous and sarcomatous tissue elements. OCS has an incidence of 2.5% (4 cases ...
  • Chronic suppurative otitis media complicated with facial paresis 
    Iutis, Vlada; Didencu, Alexandru; Noroc, Iurie; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic otitis media (COM) is a recurrent infection affecting the middle ear and/or mastoid air cells, often accompanied by a perforated tympanic membrane (TM). Additionally, COM may progress to a condition ...
  • Cochlear implantation in deaf-mute adult with partial optic nerve atrophy 
    Istrati, Andriana; Noroc, Iurie; Vetricean, Sergiu; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Congenital deafness together with that acquired at a young age represent important pathological conditions, with an incidence of about 1-3 cases per 1000 live births, being diagnosed relatively late has ...

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