• Evaluation of clinical-paraclinical particularities of frailty syndrome in the elderly 

  Popescu, Ana; Șoric, Gabriela; Negară, Anatolie; Bodrug, Nicolae; Popa, Ana; Botezatu, Adriana; Negara, Anatolie (CEP Medicina, 2026)

  Background. The aging process presents a series of age-related physiological and pathophysiological changes, including geriatric syndromes, such as frailty syndrome (FS), which is characterized by a decrease in functionality ...
• Critically low treatment success rate in extensively drug-resistant tuberculosis patients in the Republic of Moldova 

  Tewatia, Krishan; Mukherjee, Tishya; Chesov, Dumitru (CEP Medicina, 2026)

  Background. The updated definition by WHO global TB programme of XDR-TB refers to TB that is resistant to minimum one fluoroquinolone and with addition of one Group A anti-TB drug, highlights increasing emergence of ...
• Imaging diagnosis of intrahepatic volume formations 

  Sanduța, Carolina; Hotineanu, Adrian (CEP Medicina, 2026)

  Background. Liver nodules can occur both on the background of non-cirrhotic and cirrhotic liver. Early diagnosis through CT and MRI imaging examinations of benign and malignant liver lesions is essential for evaluating ...
• Imaging diagnosis of emphysematous necrotizing pancreatitis 

  Constantinov, Daria; Sanduța, Carolina (CEP Medicina, 2026)

  Background. Emphysematous necrotizing pancreatitis (ENP) is a severe form of acute pancreatitis, characterized by infected necrosis and accumulation of intra- and peripancreatic gas. Early diagnosis via computed tomography ...
• Food poisoning or adrenal insufficiency? The role of hyperkalemia in guiding the diagnosis 

  Maidanschi, Lidia; Stoica, Mihaela; Caminina, Aliona; Mornealo, Elena; Vîrtosu, Ana; Tcaciuc, Eugen (CEP Medicina, 2026)

  Background. Hyperkalemia (>5.9 mmol/L) has multifactorial causes. Although it is frequently associated with renal insufficiency, hyperkalemia is also a manifestation of adrenal insufficiency, especially during acute ...
• Hemodynamic profile associated with the induction of general anesthesia 

  Talasimov, Irina; Cîvîrjic, Ivan; Șandru, Serghei (CEP Medicina, 2026)

  Background. General anesthetics have significant effects on the hemodynamic profile of the patient, depending on comorbidities and the associated anesthetic risk. Continuous intraoperative monitoring of hemodynamic ...
• Post-cholecystectomy syndrome: causes, diagnosis and management solutions 

  Muniraju, Bhavani Challaghatta; Sârbu, Oxana (CEP Medicina, 2026)

  Background. Cholecystectomy is used in the treatment of cholelithiasis and cholecystitis, with a global incidence of over one million cases annually. Although effective, 10–30% of patients develop post-cholecystectomy ...
• Alteration of the mental status in primary hypothyroidism 

  Postolache, Danu; Vudu, Stela; Vudu, Lorina (CEP Medicina, 2026)

  Background. Thyroid hormones are essential for the optimal functioning of the central nervous system. Their deficit has well-documented adverse effects on cognitive and emotional functioning. People with hypothyroidism ...
• Current therapeutic strategies in the management of primary myelofibrosis in young adults 

  Sghibneva-Bobeico, Nina; Musteaţă, Vasile (CEP Medicina, 2026)

  Background. Primary myelofibrosis (PMF) is a Ph-chromosome-negative myeloproliferative neoplasm. In young patients (<40 years), PMF is rare and presents with diverse clinical manifestations, but it is characterized by a ...
• Evaluation of clinical and paraclinical manifestations in pseudomembranous colitis 

  Macovei, Andrei; Bezu, Ghenadie (CEP Medicina, 2026)

  Background. Pseudomembranous colitis is a severe inflammation of the colon, most associated with Clostridioides difficile infection, particularly following the use of broadspectrum antibiotics. Diagnosis is based on the ...
• Conservative treatment of osteoarthritis – a modern analysis from the perspective of international clinical guidelines 

  Basistîi, Alexandr; Pulucciu, Elena; Bețișor, Alexandru (CEP Medicina, 2026)

  Background. Osteoarthritis is the most common degenerative joint disease, affecting elderly individuals and negatively impacting mobility and daily function. Conservative treatment aims to relieve symptoms, maintain joint ...
• Effectiveness of biological treatment in rheumatoid arthritis through the prism of inflammation indices 

  Bonari, Iuliana; Nistor, Alesea; Grosu, Maia (CEP Medicina, 2026)

  Background. Rheumatoid arthritis is a systemic autoimmune disease marked by chronic synovial inflammation, causing progressive joint destruction and disability. Biological treatments, especially targeted agents, have ...
• Clostridium difficile infection as a complication of anti-tuberculosis treatment 

  Ignat, Iuliana; Chesov, Dumitru (CEP Medicina, 2026)

  Background. Clostridium difficile infection (CDI) is a potentially life-threatening complication associated with long-term antibiotic treatment. The frequency and developmental features of CDI occurring as a complication ...
• Hidronefroza la copil: reviul literaturii 

  Celac, Viviana Mihaela; Opreanu, Angelika; Bernic, Jana; Celac, Victoria (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)

  Rezumat Scopul studiului: Identificarea unor predicții clinico-paraclinici pentru determinarea conduitei medico-chirurgicale a hidronefrozei la copii în reducerea ratei complicațiilor. Obiective: sinteza și analiza ...
• Intoxicație acută severă cu etilenglicol cu evoluție oligoanurică: abordare terapeutică prin epurare extracorporală combinată (PF + HD) la adolescent. Caz clinic 

  Postolache, Sergiu; Gudumac, Eva; Ceban, Emil; Bernic, Jana; Roșu, Solange Tamara; Bașli-Selezniov, A.; Secu, V.; Ciobanu, A.; Beresteanu, C.; Ciuntu, Angela (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)

  Summary Ethylene glycol poisoning represents a contemporary medico-social problem, frequently encountered in cases of voluntary or accidental ingestion. After ingestion, ethylene glycol is metabolized in the liver by ...
• Șocul hipovolemic și deshidratarea în diareea acută la copii. Evaluarea clinică 

  Petcova, Ina; Dolghier, Lidia; Ioniuc, Ileana; Petcov, Ivan; Cornilov, Stela; Petcova, Valeria (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)

  Rezumat. Introducerea. Șocul hipovolemic este o afecțiune frecventă, dar adesea subestimată, care însoțește numeroase boli ce afectează copiii. De fapt, este cel mai frecvent tip de șoc în grupa de vârstă pediatrică la ...
• Diverticul gigant al vezicii urinare (prezentare de caz clinic) 

  Revenco, Adrian; Bernic, Jana; Seu, Larisa; Hanganu, Elena; Țarcă, Elena; Neamțu, Valeriu; Petrovici, Vergil; Gudumac, Eva (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)

  Rezumat. În articol este prezentată o anomalie congenitală renourinară – diverticul gigant al vezicii urinare, care a fost stabilit tardiv, la vârsta de 15 ani a adolescentului. Diagnosticul a fost stabilit prin examenul ...
• Abordări multidisciplinare în fibroza chistică la copil 

  Șciuca, Svetlana; Efros, Dorina; Buga, Nelea; Bernic, Jana; Selevestru, Rodica; Rusu, Ludmila; Gudumac, Eva (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)

  Rezumat Introducere: Fibroza chistică (FC) este cea mai frecventă boală genetică autosomal recesivă cu afectare multisistemică, caracterizată prin disfuncția canalului CFTR, care determină secreții vâscoase și obstrucția ...
• The role of left atrial appendage isolation in catheter ablation of atrial fibrillation: a meta-analysis 

  Semionov, Marius; Vetrilă, Snejana; Rizov, Mihail (CEP Medicina, 2026)

  Background. Pulmonary vein isolation is the main method of atrial fibrillation treatment, but it does not lead to effective outcomes in persistent atrial fibrillation, prompting investigation of other arrhythmogenic ...
• Clinico-imaging approach to multivisceral echinococcosis – case report 

  Albu, Mădălina; Toma, Cristina; Scutaru, Eugenia; Iavrumov, Ecaterina; Corlăteanu, Alexandru (CEP Medicina, 2026)

  Background. Echinococcosis is an endemic zoonotic disease caused by the larval stage of Echinococcus granulosus. The liver and the lungs are the most frequently affected organs (56% and 25%). In our country, the disease ...

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