Abstract:
Introduction. Dietary supplements should contain substances not exceeding the
maximum daily dose, otherwise they are considered drugs. The
legislation of Republic of Moldova does not require a compulsory
quantitative state control of dietary supplements.Purpose. Determination of the quantitative content of ascorbic acid in some
dietary supplements registered in the Republic of Moldova. Material and methods. It was used: five dietary supplements containing ascorbic acid:
tablets, capsules, effervescent tablets, solution and syrup; 0.1 mol/l
iodine titrant solution; 2% starch solution; OHAUS DV215 CD
electronic balance. Results. As a result of experimental research, it has been determined that the
percentage of ascorbic acid in the food supplements that were taken
for analysis was between 95.48-99.67% and the deviations from the
prescribed values were not higher than 5% (Fig. 1). The highest percentage of ascorbic acid was found in dietary
supplements in the form of tablets (99.67%), effervescent tablets
(99.62%) and capsules (98.75%), followed by syrup (97.36%) and
the lowest concentration was found in solution (95, 48%), in
which ascorbic acid is less stable due to its rapid oxidation at
contact with air. Conclusions. It was determined the content of ascorbic acid in food supplements
in the form of: tablets, capsules, effervescent tablets, solution and
syrup, which is in accordance with the values indicated on the
package.
Description:
Department of Pharmaceutical and Toxicological Chemistry, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltare
