Abstract:
INTRODUCTION. Drug interactions are of great interest because the likelihood
of concomitant administration of several drug substances is
significantly increased. While some combinations are beneficial
or, in the worst case, harmless, there are extremely dangerous
drug interactions. Their effects can go as far as altering vital
processes in the body and even death. Sometimes the severe
reactions resulting from these interactions occur unexpectedly,
other times, although they are known, they are underestimated.
Drug interactions have become a serious problem in groups
of children, due to the vulnerability of the biological and
psychological status of children.
PURPOSE. The purpose of the study was to study and evaluate the role of
the pharmacist in the management of drug interactions in
children in the community pharmacy. MATERIAL AND METHODS. A selective cross-sectional research was conducted, the
sociological survey using the semi-structured questionnaire,
with a sample volume of 100 participants. The selection of
static units was made among pharmacists from community
pharmacies in the Republic of Moldova. RESULTS. The role of the pharmacist in the management of the prevention of
drug interactions in children in community pharmacies was identified. 67.3% stating that they had experienced interactions, of which 10%
are not reported, and 84% - rarely report them. Upon detection in 88% the pharmacist contacts the prescribing
physician, and 50% refuse to release the drug. 80% consider it
appropriate to implement alert information systems for interactions,
especially in children. CONCLUSIONS. As a result of the study, a number of problems were identified regarding
drug interactions in children, highlighting the role of the pharmacist in
their management.
Description:
Chair of Social Pharmacy „Vasile Procopişin”, ”Nicolae Testemitanu” State
University of Medicine and Pharmacy, Chisinau, Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltare