Abstract:
Abstract
Abstract. Background: growth hormone stimulates longitudinal growth of human bones, including the maxillofacial region. The effect of growth hormone on the growth of the mandibular condylar process is not well understood. This article is relevant for understanding the effect of growth hormone treatment on craniofacial structures.
Purpose: to assess the effect of the growth hormone of the pituitary gland on the condylar process of the lower jaw.
Material and methods – analysis of literature.
Results: Growth hormone is produced by somatotrophs of the anterior pituitary gland under the control of the
hypothalamus. Growth hormone is the main hormone that stimulates linear growth. It promotes longitudinal bone
growth, differentiation of internal organs, and development of muscle tissue. The main effects of growth hormone
at the bone level are to stimulate cartilage growth and protein synthesis. Growth-stimulating effects of growth
hormone are mediated through insulin-like growth factor, which is synthesized mainly in the liver under the influence of somatotropin. Growth hormone and IPFR-I affect bone metabolism, including effects on bone modeling
and remodeling, have a pronounced effect on the metabolism of bone structures in the craniofacial region, and are
the main regulators of postnatal growth and development. The condylar cartilage of the mandible is classified as
fibrous cartilage, and the most superficial layer of the condylar cartilage is dense fibrous tissue. Condylar cartilage
adapts to environmental influences and therefore alters chondrogenesis or endochondral ossification.
Conclusions: 1.with the injection of the hormone, the increase in the growth of the lower jaw. 2.The length of
the head of the lower jaw increases. 3. The nature of the growth of the lower jaw, treatment of somatotropic insufficiency and underdevelopment of the jaw.
Description:
ФГБОУ ВО Тверской ГМУ Минздрава России, Тверь Россия, кафедра анатомии, Conferința Ştiinţifică Internaţională ”Probleme actuale ale morfologiei” dedicată celor 75 de ani de la fondarea Universităţii de Stat de Medicină și Farmacie Nicolae Testemiţanu, Chişinău, 30-31 octombrie 2020