Влияние гормона роста на мыщелковый отросток нижней челюсти (обзор литературы)

Abstract

Abstract Abstract. Background: growth hormone stimulates longitudinal growth of human bones, including the maxillofacial region. The effect of growth hormone on the growth of the mandibular condylar process is not well understood. This article is relevant for understanding the effect of growth hormone treatment on craniofacial structures. Purpose: to assess the effect of the growth hormone of the pituitary gland on the condylar process of the lower jaw. Material and methods – analysis of literature. Results: Growth hormone is produced by somatotrophs of the anterior pituitary gland under the control of the hypothalamus. Growth hormone is the main hormone that stimulates linear growth. It promotes longitudinal bone growth, differentiation of internal organs, and development of muscle tissue. The main effects of growth hormone at the bone level are to stimulate cartilage growth and protein synthesis. Growth-stimulating effects of growth hormone are mediated through insulin-like growth factor, which is synthesized mainly in the liver under the influence of somatotropin. Growth hormone and IPFR-I affect bone metabolism, including effects on bone modeling and remodeling, have a pronounced effect on the metabolism of bone structures in the craniofacial region, and are the main regulators of postnatal growth and development. The condylar cartilage of the mandible is classified as fibrous cartilage, and the most superficial layer of the condylar cartilage is dense fibrous tissue. Condylar cartilage adapts to environmental influences and therefore alters chondrogenesis or endochondral ossification. Conclusions: 1.with the injection of the hormone, the increase in the growth of the lower jaw. 2.The length of the head of the lower jaw increases. 3. The nature of the growth of the lower jaw, treatment of somatotropic insufficiency and underdevelopment of the jaw.