Unele particularităţi epidemiologice şi managementul antibioticoterapiei infecţiilor septico-purulente în endoprotezarea articulaţiilor coxofemurale şi de genunchi

Abstract

Some epidemiologic particularities and management of treatment with antibiotics of septic-purulent infections of hip and knee joints endoprosthesis Analyzing medical records of patients with endoprosthesis treated in the orthopaedic departments of PMSI CHTO, during 2011- 2015, showed various septic-purulent complications in 37 (5.36%) patients hospitalized in the department of septic surgery. However, analyzing the prosthesis patients with various septic-purulent infections, we found that the incubation period is on average about 18 months. As a result of bacteriological study, 33 bacterial strains were detected, which demonstrates the polyetiologic nature of nosocomial infections. In 40% of those investigated, were found 2 to 3 strains of bacteria. The total resistance to all groups of antibiotics was observed in 28.6% of cases, sensitivity – 71.4%. Descriptive study examines the incidence of nosocomial infections declared, but also those undeclared by a retrospective review of medical records. Septic-purulent infections were found in 5.36% cases for 100 surgeries. Mainly Gram-positive infections, which represented 75.75% of the total number of microorganisms detected, Gram negative – 24.25%, S. epidermidis, S. aureus, S. hemoliticus, P. aeroginosa, E. coli. A better sensitivity to antibiotics were found in microorganisms of Staphylococcus and Streptococcus genus, including S. aureus (91.82%), S. epidermidis (76%), S. aeroginosa (85.7), Acinetobacter (75%), E. coli (31.3%), P. aeroginosa (16%).