Abstract:
Abstract
Background: In experiment investigated the response of neurons of the sensorimotor cortex to ionizing radiation
in small doses. The high sensitivity of neurons to the studied factor, but changes in most cases do not go beyond the biological norm, they are reversible, but provides a background for the development of pathological processes (mental and
neurological disorders).
Material and methods: White male rats irradiated on the γ-rays 60Co single dose of 0,5 Sv with a dose rate of 0,5
Gy/h. Material by months after irradiation. The material taken away at different times post-radiation period. Counted the
number of neurons with different tinctorial properties, was calculated the nerve cell index. The obtained data were statistically processed, followed by mathematical modeling.
Results: Irradiation causes a more pronounced reaction layer III neurons of the cortex. Increasing the number of
neurons with degenerative changes revealed by the end of the observation period. Indicators of nerve cell death index indicate parts of the nerve cells, which affects the number of neurons. Analysis of variance confirmed the absence of marked
morphological differences between control and exposed animals.
Conclusions: The high sensitivity of neurons to ionizing radiation, but the changes do not go beyond the biological
norm. Revealed periods of activation alterative processes and relative prosperity, is a manifestation of cellular adaptation.
Changes are reversible after exposure, but create the background for the development of pathological processes. Mental
and neurological disorders are detected after irradiation neuromorphological correlates.
Description:
Кафедра нормальной анатомии человека, Воронежский государственный медицинский университет им. Н. Н. Бурденко, Воронеж, Россия, Кафедра медико-биологических дисциплин, Воронежский государственный институт физической культуры, Воронеж, Россия, Conferința Ştiinţifică Internaţională ”Probleme actuale ale morfologiei” dedicată celor 70 de ani de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemiţanu”, Chişinău, 15-16 octombrie 2015