Abstract:
Osteoporosis is a metabolic bone disease, characterized by
progressive bone mineral loss, increased bone fragility and
susceptibility to low-energy fractures. Until the development
of fragility fractures, the patients are mostly asymptomatic,
the screening process relying heavily on fracture risk assessment tools. Among them FRAX is considered to be
one of the most reliable, with a net superior informativity.
Nevertheless, due to a high variation of fragility fracture
incidence in different geographical areas, country-specific
FRAX models are required to assess fracture risk in a certain population. Objective: the purpose of this study is to
study the incidence of fragility fracture in a defined catchment area from Republic of Moldova in order to develop a
country-specific FRAX tool. Results: since November 2016,
a country specific fracture risk assessment tool is available
in the Republic of Moldova.