Hyperleptinemia and leptinoresistance to patients with arterial hypertension in relation with metabolic syndrome
There were evaluated 294 patients with arterial hypertension in relation with metabolic syndrome and the role of leptine in metabolic
changes to these patients. Hyperleptinemia was determined to 83.3% among patients with arterial hypertension and metabolic syndrome.
Hyperleptinemia increased in correlation with obesity degree. The relation between hyperleptinemia with body mass index and
hyperinsulinemia shows their key role in pathogenesis of the insulin resistance in metabolic syndrome.
Au fost evaluați 294 pacienți hipertensivi în contextul sindromului metabolic și rolul leptinei în modificările metabolice la acești pacienți.
Hiperleptinemia a fost determinată la 83,3% dintre pacienţii hipertensivi cu sindrom metabolic, s-a intensificat pe măsura creşterii gradului
de obezitate. Relaţia dintre hiperleptinemie cu indicele masei corporale şi hiperinsulinemie reflectă rolul-cheie a lor în patogeneza
insulinorezistenţei din sindromul metabolic.
