Evaluarea activităţii lupusului eritematos systemic

Abstract

Background: precise measurement of SLE activity remains a difficult task due to the complex multisystem nature of the disease. Data were collected and analyzed on 72 consecutive patients. The activity of disease was evaluated by SLEDAI and PGA, also Morisky treatment aderence scale. Low disease activity was determined in a third of patients (30.6%), and active disease (63.9%) remains high, in the remission group were 4 patients (5.5%). The professional status evaluation noted that 32% of SLE patients were employed full-time, 22.2% were disabled, 19.5% were unemployed, housekeepers and trainees, 15.3% were partially recruited and 11.1% retired. High level of SLEDAI is a strong and statistically significant predictor of persistence of the disease activity. At the time of the diagnosis, the high activity of SLE predicts maintenance of chronic activity.