Abstract:
Neurofibromatosis type 1 (NF1) is a multisystem genetic
disorder that is characterized by cutaneous findings, most
notably café-au-lait spots and axiliary freckling by skeletal
dysplasia, and by the growth of both benign and malignant
nervous system tumors, most notably benign neurofibromas.
Cardiovascular manifestations of neurofi bromatosis are:
hypertension, valvular stenosis, congenital heart defects,
complete cardiac block, hipertrofic cardiomyopathy, myocardial infarction, coronary spasm.