The Moldovan Medical Journal 2021: Recent submissions

  • Role of nutritional and lifestyle factors on the Amyotrophic Lateral Sclerosis progression. Results from a multicenter cross-sectional study 
    Cucovici, Aliona; Ivashynka, Andrei; Fontana, Andrea; Lisnic, Vitalie; Leone, Maurizio A. (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Amyotrophic Lateral Sclerosis is a devastating, untreatable motor neuron disease with unknown causes, but nutritional and lifestyle factors may play a role. To check this hypothesis, we conducted a multicentre ...
  • Treatment of acute ischemic stroke by systemic thrombolysis combined with endovascular thrombectomy: case report 
    Condrea, Alexandra; Zota, Eremei; Crivorucica, Igor; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: A small number of acute ischemic stroke (AIS) patients meets eligibility criteria for systemic thrombolysis (ST) with recombinant tissue plasminogen activator, but its efficacy for large vessel occlusion is ...
  • Management of brain tumor-related epilepsy: case report 
    Condrea, Alexandra; Aftene, Daniela; Chiosa, Vitalie; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Patients with brain tumor related epilepsy present a complex therapeutic profile and require a unique and multidisciplinary approach. Difficulty in managing epilepsy in patients with brain tumors stems from ...
  • Co-occurrence of voltage-gated calcium channel and acetylcholine receptor antibodies: case report 
    Bubuioc, Ana-Maria; Cernei, Irina; Gheceva, Oxana; Gavriliuc, Mihail; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Voltage-gated calcium channels (VGCC) antibodies are generally associated with Lambert Eaton myasthenic syndrome (LEMS). Their coexistence with acetylcholine receptor (AchR) antibodies, which are specific for ...
  • Efficacy of implementation of the FeSS protocol in thrombolysed stroke patients from Institute of Emergency Medicine 
    Zota, Eremei; Crivorucica, Igor; Belitei, Doina; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Implementation of intravenous thrombolysis for acute ischemic stroke has significant impact on stroke outcome by reducing disability and post-stroke mortality rates. However, high risk for developing early ...
  • Update on current knowledge on poststroke epilepsy 
    Cucusciuc, Cristina; Gasnas, Alexandru; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The main cause of seizures in adults beyond the age of 60s is represented by cerebrovascular diseases, mainly hemorrhagic and ischemic strokes. Poststroke epilepsy (PSE) is one of their complications, that ...
  • Familial epilepsy – clinical-epidemiological characteristics and next-generation sequencing in the Republic of Moldova’s population 
    Gasnas, Daniela; Chelban, Viorica; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Although several theories are implicated in the origin of epilepsy, its cause is still unknown in about 50% of cases. To associate a gene with epilepsy for the first time, families with multiple affected members ...
  • Immunoenzymatic changes in ischemic stroke in children 
    Sprincean, Mariana; Hadjiu, Svetlana; Lupușor, Nadejda; Griu, Corina; Cuznet, Ludmila; Racovita, Stela; Feghiu, Ludmila; Calcii, Cornelia; Revenco, Ninel; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Ischemic stroke (IS) in children is a major neurological emergency, being a primary cause of morbidity and mortality. The incidence of IS is 2 – 13:100000 children or 1:4000 in neonatal period. The purpose of ...
  • Intraoperative ultrasonography in brain tumor surgery: 5-year experience 
    Galearschi, Vasile; Mindrigan, Eugeniu; Andrușca, Alexandru; Andronachi, Victor (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Ultrasonography is an accessible imaging modality that provides real-time guidance with minimal risk or additional time. There is a strong correlation between ultrasonography and postoperative computed tomography ...
  • Clinical course and outcomes in immunocompromised patients with neuroinfections 
    Manole, Elena; Grosu, Oxana; Odainic, Olesea; Gavriliuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Medical conditions that weaken the immune system facilitate the development of the infections of the nervous system and modify its usual clinical pattern. The aim of our study was to analyze the clinical course ...
  • Clinical evaluation of patients with non-aneurysmal and non-traumatic subarachnoid hemorrhage 
    Dumanscaia, Maria; Tibirna, Natalia; Dorobet, Alexandru; Odainic, Olesea; Manole, Elena (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Subarachnoid haemorrhage (SAH) accounts for about 3% of all strokes and 10% of haemorrhagic strokes, with a mortality of up to 50% of cases. In 85% of cases SAH is caused by an aneurysmal rupture, 10% – are ...
  • Cognitive impairment and neuropsychiatric manifestations at the onset of multiple sclerosis: case report 
    Macovenciuc, Alina; Cernei, Irina (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that mainly affects young adults and leads to a wide range of signs and symptoms, including physical, cognitive and psychiatric ...
  • Vestibular findings in multiple sclerosis patients 
    Sangheli, Marina; Gavriliuc, Olga; Cretu, Diana; Nederita, Mirela; Gavriliuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Dizziness, vertigo, and imbalance combined with other clinical signs of multiple sclerosis (MS) patients like weakness, sensory loss, ataxia, may result in falls and accidents, as well as restrictions on outdoor ...
  • Preliminary results of the ENERGY study (Ean NEuro-covid ReGistrY) in the Republic of Moldova 
    Popa, Vera; Grosu, Oxana; Lisnic, Vitalie; Gavriliuc, Mihail; Odainic, Olesea; Manvelov, Anastasia; Cebotari, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: ENERGY registry developed by the European Academy of Neurology studies neurological manifestations in patients with COVID-19 infections. Diomid Gherman Institute of Neurology and Neurosurgery joined these ...
  • Causes of traumatic brain injuries in the Republic of Moldova 
    Mindrigan, Eugeniu; Andrușca, Alexandru; Andronachi, Victor; Galearschi, Vasile (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Traumatic brain injury (TBI) is a major source of health loss and disability worldwide. Many survivors live with significant disabilities, resulting in major socioeconomic burden. Annually, in Europe are ...
  • Overview of vascular dementia 
    Gavriliuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Vascular disease contributes from 25 to 50 percent of cases of dementia, and vascular dementia is the second most common type of dementia in clinical and population studies, surpassed only by Alzheimer’s ...
  • Management of non-traumatic, non-aneurismal intracerebral hemorrhage 
    Gavriliuc, Pavel; Andronachi, Victor; Andrușca, Alexandru; Gavriliuc, Mihail; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Intracerebral hemorrhage is the second most common form of stroke after ischemic stroke. Common causes of spontaneous intracerebral hemorrhage are: hypertension, amyloid angiopathy, aneurysmal hemorrhages and ...
  • Pulmonary embolism in stroke patients: autopsy results study 
    Baitoi, Silvia; Grosu, Oxana; Manole, Elena; Rotaru, Lilia; Odainic, Olesea; Corcea, Galina (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Pulmonary embolism is a major contributor to in-hospital mortality after stroke and accounts for up to 50% of early deaths. The clinical picture could be unremarkable, so the complication is not recognized in ...
  • Atypical presentation of glioma tumor: autopsy results 
    Nacu, Gabriela; Grosu, Oxana; Moldovanu, Ion; Odobescu, Stela; Rotaru, Lilia; Corcea, Galina; Caliga, Ioana (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: A brain tumor can appear in post-ischemic areas, and due to increased proliferation, venous thrombosis, hypercoagulability, and local factors it can induce stroke. These two conditions can mimic each other. ...
  • The Moldovan Medical Journal. September 2021, Vol. 64, No 3 
    Unknown author (The Scientific Medical Association of the Republic of Moldova, 2021)
    The Moldovan Medical Journal is an international scientific double-blind peer-reviewed periodical edition, 4 per year, of the Scientific Medical Association of the Republic of Moldova designed for specialists in the areas ...

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