Abstract:
Abstract.
Background: High mortality and disability of patients with critical and supercritical burns, long-term treatment, unsatisfactory aesthetic and functional
results lead to the search for ways to provide assistance aimed at counteracting the formation of a mass of necrotic tissue, which is crucial for life or death
of the victim.
Material and methods: The experimental study was performed on 60 sexually mature Wistar rats, which were on a regular diet and weighed 150-160 g.
The experimental animals were divided into the main and control groups and were used to simulate burns with boiling water of IIb degree.
Results: The traumatic effect of hyperthermic exogenous and endogenous damage factors of the animals in the main group were immediately neutralized
by a gauze napkin soaked in water at a temperature of 18-20 °
C immediately after the simulation of burns, the duration of which became the criterion
for dividing them into subgroups. In animals of subgroup 1 the time of application of a wet wipe to the burn area was 1 min., in the 2nd subgroup it was
5 min., 3rd subgroup – 10 min., 4th subgroup – 15 min., 5th subgroup – 20 min. The application napkin was changed when it was heated to 34 °C. Such
applications were not performed to the animals of the control group.
Conclusions: The conclusion was made on the necessity of prompt neutralization of traumatic action of hyperthermic exogenous and endogenous damage
factors as the main elements of burn wound depth. For a broader understanding of action mechanisms of the suggested technology of self-help and mutual
first aid as well as the nature of the impact of neutralization directly on the tissues, it is advisable to supplement the research with morphological methods.
Description:
Department of General Surgery, National Pirogov Memorial Medical University, Vinnytsya, Ukraine
