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The penetrating ability of Silybum marianum flavolignans in vitro

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dc.contributor.author Soltan, Ilya
dc.contributor.author Lukashou, Raman
dc.date.accessioned 2021-10-08T13:10:14Z
dc.date.available 2021-10-08T13:10:14Z
dc.date.issued 2021
dc.identifier.citation SOLTAN, Ilya, LUKASHOU, Raman. The penetrating ability of Silybum marianum flavolignans in vitro. In: Revista Farmaceutică a Moldovei. 2021, vol. 45, nr. 1, pp. 67-71. ISSN 1812-5077. en_US
dc.identifier.issn 1812-5077
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/18144
dc.description Belarusian State Medical University, Minsk, Republic of Belarus en_US
dc.description.abstract Rezumat. În articol sunt prezintate rezultatele determinării capacităţii de penetrare a flavolignanilor din armurariu, utilizând modele in vitro. Cea mai bună capacitate de penetrare a flavolignanilor este asigurată de combinaţia extractului uscat de armurariu cu suma saponinelor totale de lemn dulce (89,57% masă), standardului de silimarină cu aceleași saponine (85,75% masă), extractului uscat de armurariu cu lecitină de soia (84, 37% masă). La utilizarea dodecilsulfatului de sodiu (SDS), are loc o diferenţiere clară a curbelor de absorbţie, fapt ce permite utilizarea SDS ca model pentru studierea absorbţiei flavolignanilor. en_US
dc.description.abstract Abstract. The article presents the results of determining the penetrating ability of milk thistle flavolignans using in vitro models. The best penetrating abilityof flavolignans is provided by a combination of milk thistle dry extract with the total licorice saponins (89.57% by weight), standard of sylimarinewith saponins (85.75% by weight), dry extract with soy lecithin (84, 37% by weight). With the use of sodium dodecyl sulfate (SDS), a clear differentiation of the absorption curves occurs, which may allow the use of SDS as a model for studying the absorption of flavolignans. en_US
dc.language.iso en en_US
dc.publisher Asociația Farmaciștilor din Republica Moldova en_US
dc.relation.ispartof Revista Farmaceutică a Moldovei en_US
dc.subject Milk thistle en_US
dc.subject penetrating ability en_US
dc.subject flavolignans en_US
dc.subject.ddc CZU: 582.998.1:547.9 en_US
dc.title The penetrating ability of Silybum marianum flavolignans in vitro en_US
dc.title.alternative Capacitatea penetrantă a flavolignanilor din Silybum marianum in vitro en_US
dc.type Article en_US


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