Abstract:
Background: Boron was classified by the World Health Organization as ‘possible essential elements for human health’. It can be found in different forms
in the environment, has beneficial effects on bones and its deprivation can impair calcium and magnesium metabolism and bone development, their
health and maintenance. Dietary boron supplementation can help prevent and manage degenerative and inflammatory bones and articular diseases, such
as arthritis, osteoarthritis, rheumatoid arthritis and osteoporosis. Relevant articles were identified in PubMed, Google Scholar, ProQuest, and Scopus
databases published until June 2021, describing the role of boron in the functioning of the osteoarticular system.
Conclusions: From organic and inorganic boron forms that can enter the human body, organic plant based boron compounds are highly bioavailable. In
the functioning of the osteoarticular system boron acts by regulation of calcium and magnesium metabolism, enhancing the vitamin D activation process
and influencing serum steroid hormone levels. A boron intake equal to or higher than 3 mg per day can help prevent/or correct arthritis, osteoporosis
and osteoarthritis. Calcium fructoborate can reduce pain, joint discomfort and increase endogenous vitamin D level in patients with osteoarthritis. Boron
may play a role in pathophysiology of rheumatoid arthritis and its severity and a supplementation with boron element may be useful.
Description:
National Agency for Public Health, Chisinau, the Republic of Moldova,
BioBoron Research Institute, Craiova, Romania