Profile of the quality of life in patients with liver cirrosis after splenectomy

Abstract

Introduction. Once medical progresses have improved, which determined health care and therapeutic result improvement, rising the quality of life has become a major desideratum, with important contribution in the elaboration of the therapeutical decision Materials and methods. It has been realized a bidirectional clinical trial for a period of 11 years, which evaluated the surgical impact on the quality of life of 97 patients, diagnosed with hepatic cirrhosis. The research took place at Surgery nr2 department, hepatobiliopancreatic surgery department of the Republican Hospital in 2005-2016 period.The patients in the study, benefited of selective, scheduled surgical treatment. The quality of life was assessed using the SF-36 and SF-LDQOL questionnaires. Results. Postoperatively, patients with liver cirrhosis and associated portal hypertension (89%) noted a significant improvement in the quality of life in both the control group (p≤0,002) and the preoperative stage (p≤0,001). Remarkable in all the operated patients, in the first year after the intervention, the quality of life improved in moderate/good quantification in 78.9% of patients. Conclusion. Patients with liver cirrhosis have significant impairments in quality of life. The possibility of improving the quality of life is in direct relation to the stage of liver cirrhosis, type of the surgical intervention and rate of postoperative complications. Life quality assessment studies are useful, because it provides important information for optimizing therapeutic methods, reduction of morbidity and improving prognosis.