Abstract:
Background: Glaucoma represents a significant public health concern as it is the second leading
cause of blindness after cataracts [Thomas S, Hodge W. Malvankar-Mehta MPLoS One. 2015]. It
is estimated that 57.5 million people worldwide are affected by primary open-angle glaucoma
[Quigley HA, Br J Ophthalmol. 2006]. It is a multifactorial optic degenerative neuropathy
characterized by the loss of retinal ganglion cells, being an irreversible process [Harasymowycz
P, et al. J Ophthalmol. 2016.].
Aim: We report a case of filtration surgery treatment in experimentally induced ocular
hypertension.
Case report: After obtained the induced ocular hypertension, by using a local subconjunctival
injection of 0,7ml betamethasone suspension in one eye in New Zealand rabbit, it was performed
the filtration surgery, in aseptic conditions, under general and local anesthesia. The filtration
surgery was performed on 2 white rabbits, with the implantation of a new design model of
antiglaucoma shunt. During the surgery, it was implemented and studied the methods and
techniques of implantation of the filtering device. It was monitoring the IOP postoperative and
the ocular status for a period of 6 months.
Conclusion: The surgical procedure of antiglaucomatous shunt with valve implantation is an
efficient one in the induced ocular hypertension in rabbits, which opens new possibilities in
glaucoma treatment research.
