Abstract:
Abstract
Objectives. Study of clinical manifestations in psoriatic arthritis: enthesitis, dactylitis, peripheral arthritis, axial
arthritis, skin manifestations, for early diagnosis, which
would allow the establishment of an adjusted treatment
and the elaboration of measures to prevent complications.
Materials and methods. The performed clinical study
has an analytical-observational retrospective and included the patients who were hospitalized in the Rheumatology and Arthrology departments of the “Timofei Moşneaga” Republican Clinical Hospital during 2015-2021. The
study included 103 patients with psoriasis (47 men and
56 women) with various clinical forms of psoriasis and different ages.
Results. The clinical examination of primary or referred patients with cutaneous manifestations, revealed peripheral arthritis in 15 patients (24.6%), dactylitis – in 37
(60.7%), heel pain was detected in 32 (52.5%), axial arthritis – in 30 (49.2%), enthesitis, distal interphalangeal arthritis and tendonitis were not detected. Those who primary or
referred with joint manifestations, in 35 (57.4%) of patients
was present peripheral arthritis, dactylitis in 40 (65.6%),
enthesis of the elbow joints in 11 (18%), knee joints - in 8
(13.1%), the calcaneal region - to 25 (41%), arthritis of the
distal interphalangeal joints was detected in 21 (34.4%),
tendinitis - to 13 (21.3%).
Discussions. The obtained results allow us to state that
one of the directions in improving the diagnosis of PsA consists in the use of ultrasound examination and MRI imaging
of the joints of the hands and feet. This makes it possible to
effectively identify the characteristic of enthesopathy, edema of tissues, as well as destructive changes in the joints of
the hands and feet.
Conclusions. In the study group of patients with psoriasis, in 25 (24.2%) no joint damage was detected. The
frequency of detection of psoriatic arthritis and other
rheumatic diseases (rheumatoid arthritis, osteoarthritis,
ankylosing spondylitis etc.) was 59.2% and 16.6%, respectively, 32 (52.5%) out of 61 (59.2%) patients with
PsA were primarily diagnosed. The sensitivity and specificity of the mPEST (Psoriasis Epidemiology Screening
Tool) questionnaire in relation to the CASPAR criteria
were 77% and 69% respectively. The highest indicators
of sensitivity, specificity and accuracy in the diagnosis of
PsA has ultrasound and MRI: 88%, 92%, 89% and respectively, 89%, 94%, 91%
