1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Immunostimulation of local immunity in the complex treatment of chronic tonsillitis in children 
    Timuș, Cristina; Ababii, Polina; Danilov, Lucian; Nacu, Viorel (CEP Medicina, 2024)
    Background. After healing the palatine tonsils in the complex conservative treatment of chronic tonsillitis, an important role is the stimulation of local immunity by applying autologous mononuclear cells. This is done ...
  • A new approach in the treatment of optic nerve atrophy using mesenchymal stem cells. A systematic review 
    Țaralunga, Tatiana; Paduca, Ala; Nacu, Viorel (CEP Medicina, 2024)
    Background. Tissue engineering is a progressing field that unites cells, biomaterials and biochemical factors focused at replacing, maintaining and substituting different kind of tissues. A major role is played by the ...
  • Menstrual blood-derived stem cells: milestones and future prospects for regenerative medicine 
    Goreacii, Ana; Nacu, Ana-Maria; Țaralunga, Tatiana; Nacu, Viorel (CEP Medicina, 2024)
    Background. Stem cell therapy is the future of medicine as research into incurable diseases and injuries continues to grow. Stem cells are difficult to obtain because of ethical conflicts, sampling difficulties or high ...
  • Porcine dermis - a source of biomaterial modelling by tissue engineering 
    Macagonova, Olga; Cociug, Adrian; Țaralunga, Tatiana; Ciobanu, Vladimir; Braniște, Tudor; Buza-Zueva, Anastasia; Nacu, Viorel (CEP Medicina, 2024)
    Background. Tissue engineering is a branch of regenerative medical technology that helps replace damaged tissue using appropriate scaffolds, living cells and growth factors. Collagen-based scaffolds are attractive products ...
  • Rehabilitation of patients with post-sequestrectomy of the jaws with the use of the Osteostimulin-C 
    Ștefaneț, Veronica; Rusu-Radzichevici, Natalia (CEP Medicina, 2024)
    Background. Toxic osteomyelitis is an inflammatory origin pathology, which occurs in the jaws following the consumption of drugs with a high content of phosphorus and ephedrine, following treatment with bisphosphonates ...
  • Amniotic membrane in ophthalmology 
    Iacubițchii, Maria; Moscalciuc, Alina; Paduca, Ala; Bendelic, Eugeniu (CEP Medicina, 2024)
    Background. Amniotic membrane (AM) represents a thin membrane on the inner part of the placenta (A. C. Mamede, 2012) that can be used in ophthalmology, dentistry, urology, burn units, otorhinolaryngology, gynecology, and ...
  • The results of the treatment of trophic ulcers of the lower limbs by applying autologous platelet-rich fibrin 
    Ceban, Marina; Anghelici, Gheorghe; Zugrav, Tatiana; Pisarenco, Sergiu; Vasiliev, Radu (CEP Medicina, 2024)
    Background. The most common cause of lower limb ulcers is chronic venous insufficiency.Up to 48% of patients with trophic ulcers are at the age of maximum productivity. 67% of patients with trophic ulcers become disabled, ...
  • Autolog tranplantation of platelet rich fibrin in inguinal hernia repair in liver cirrhosis 
    Pisarenco, Sergiu; Anghelici, Gheorghe; Zugrav, Tatiana; Ceban, Marina; Vasiliev, Radu (CEP Medicina, 2024)
    Background. The objective of this study is to provide autologous platelet-rich fibrin transplantation in inguinal hernia repair in liver cirrhosis with ascites. Materials and methods. A study was conducted on 28 patients ...
  • Osteo-cellular graft in the wrist instability. Clinical case 
    Iacubițchii, Vitalie; Vacarciuc, Ion; Cojocaru, Ștefan; Buzu, Dumitru; Nacu, Viorel; Caproș, Nicolae (CEP Medicina, 2024)
    Background. The wrist or carpal instability means any disturbance of the static and dynamic balance of forces at the wrist under the conditions of daily living [Linscheid, 1972]. The cause of wrist instability in 95% is ...
  • Amniotic membrane transplantation: importance and clinical indications 
    Toma, Maria Mirabela; Porada, Sergiu; Paduca, Ala (CEP Medicina, 2024)
    Background. Amniotic membrane transplantation has been recently gained wide-spread attention as a new method for reconstruction of the ocular surface. It is used in ophthalmology as a substrate for the growth of ...
  • The use of autotransplanted and homotransplanted septal cartilage in rhinoplasty and rhinoseptoplasty surgeries 
    Osman, Victor; Osman, Vitalie; Vetricean, Sergiu; Furculița, Daniel; Nacu, Viorel (CEP Medicina, 2024)
    Background. Surgical interventions for nasal reshaping, such as rhinoplasty and rhinoseptoplasty, have gained significant popularity among the population. Currently, these procedures are increasingly performed ...
  • Amniotic membrane transplantation into lower limb ulcers 
    Mihaluța, Viorica; Stoian, Alina; Ignatova, Olga; Raischi, Ion; Verega, Grigore; Nacu, Viorel (CEP Medicina, 2024)
    Background.There are many applications of the amniotic membrane in regenerative medicine, it serves as a source of stem cells and potent growth factors and like a very biocompatible natural ...
  • The thermal stability of collagen extracted from the umbilical-placental complex 
    Jian, Mariana; Ficai, Anton; Oprea, Ovidiu Cristian; Motelica, Ludmila; Cobzac, Vitalie; Mostovei, Andrei; Nacu, Ana-Maria; Ficai, Denisa; Nacu, Viorel (CEP Medicina, 2024)
    Background. Collagen is the most abundant protein in animals. As part of the extracellular matrix it presents a true material for biomedical applications due to its versatility [1, 2]. An essential parameter of collagen ...
  • Decellularization techniques of dental pulp 
    Samson, Stella; Nacu, Viorel (CEP Medicina, 2024)
    Background. Endodontic regeneration shows promise in treating dental pulp diseases, however, no suitable scaffolds exist for pulp regeneration. Acellular natural extracellular matrix is a favorable scaffold ...
  • Improvement of transplant services at the regional level, primary factor of the quality of human life 
    Caușan, Corina; Ivan, Daniel-Cornel; Radu, Ghenadie (CEP Medicina, 2024)
    Background. In the context of the research of a wide range of applications in the field of transplantology, the promotion of this type of services is aimed at, as well as the formation of socio- economic ...
  • Non-endothelial CD34 positive stem cells of the umbilical cord and placental tissue 
    Globa, Lilian; Globa, Tatiana; Pelin, Elina; Globa, Elena; David, Valeriu (CEP Medicina, 2024)
    Background. Stem cells are unspecialized cells, but with a high capacity for differentiation, multiplication, and self-renewal, essential for the tissue regeneration. The placenta and umbilical cord are rich sources of ...
  • Evaluation of non-viable corneal grafts from the human tissue bank in the Republic of Modova 
    Cociug, Adrian; Macagonova, Olga; Cobzac, Vitalie; Cușnir, Valeriu; Nacu, Viorel (CEP Medicina, 2024)
    Introduction: Corneal preservation methods with the preservation of a maximum number of viable endothelial cells has been and remains one of the challenges of Eye Banks worldwide. There are three main approaches to the ...
  • Magnetoliposomes containing bioactive molecules as nanocarriers for biological applications 
    Zara-Danceanu, Camelia-Mihaela; Lăbușcă, Luminița; Herea, Daniel; Minuti, Anca Emanuela; Stavila, Cristina; Chiriac, Horia; Lupu, Nicoleta (CEP Medicina, 2024)
    Background. Proprietary magnetic nanoparticles (Fe3O4) with diameters around 40 nm were synthesized by the coprecipitation method and coated with oleic acid. The OA-Fe3O4 magnetic nanoparticles ...
  • Use of platelet-rich plasma in burn patients 
    Chornopyshchuk, Roman; Grebeniuk, Dmytro; Nazarchuk, Oleksandr; Burkovskyy, Mykola; Kravchuk, Vitalii; Sidorenko, Ludmila; Rotaru, Ludmila; Chornopyshchuk, Nataliia (CEP Medicina, 2024)
    Background. The use of platelet-rich plasma remains a promising area of medicine. The use of plasma, enriched with platelets, in the complex management of patients with burns, is of particular interest, especially in ...
  • Agent-based modeling: revolutionizing tissue engineering 
    Iapăscurtă, Victor (CEP Medicina, 2024)
    tissues to replace or repair damaged organs. Achieving success in tissue engineering requires a deep understanding of complex cellular behaviors and interactions. Traditional research methods, while valuable, may not ...

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