The intricate pathways in ageing

Abstract

Summary Background. Researchers tried to find out how age-related pathologies can be prevented by keeping the biomarkers levels under control since their changes might induce abnormalities. The purpose was to analyze aspects that might accelerate, and fight off the action of endogenous and exogenous factors on the metabolism of aging. Material and methods. This study is based on the critical analysis of 35 literature sources out of 74 selected from PubMed, NCBI, Google Scholar data that highlight the most essential concepts. Results. Biological age represents the modified aspects of metabolism and physiological processes. The antioxidant system and reactive oxygen species play a key role in slowing down, and accelerating the aging metabolism; genetic markers detect the aging factors; genome mutations are responsible for premature aging. Conclusions. Hence, it’s important to make a balance between a healthy lifestyle, a proper skincare routine, and maintaining cognitive functions, in order to hope for a “successful aging” by preventing diseases and increasing life expectancy.