Abstract:
Background: Antibiotics have had a profound impact on humanity’s health, by improving our ability to prevent, cure and reduce the transmission of
many infectious diseases. It is widely known, that the unnecessary or inappropriate use of antibiotics, occurs up to 50% of prescriptions only in the United
States and Canada. Fortunately all negative impact on the human health can be roughly imagined.
Material and methods: For this study we used the data of a six-year (2009-2014) period in the Emergency Medicine Institute and their main subdivisions
which show the consumption dynamics of antibacterials use in natural indexes.
Results: The total annual medium consumption of antimicrobials was registered as the following: ICD 1796.98 DDD/1000, SSOTD 566.12 DDD/1000
and EMI 584.05DDD/1000, with the parenteral to enteral forms share of respectively 94.67% to 5.33%, 85.62% to 14.38% and 83.52% to 16.48%. Five from
nine main groups: beta-lactam antibacterials, penicilins, other beta-lactam, aminoglycoside, other antibacterials and quinolone antibacterials registered
around 90% of all antibiotics consumption. Comparatively to Australian hospitals and hospitals other worldwide countries in EMI consumption per
DDD/1000 was lower: by 3.39 and 2.22 times for tetracyclines, by 5.1 and 4.63 for beta-lactam and penicilins, as well as by 2.55 and 1.63 for macrolides
and lincosamides.
Conclusions: The obtained data about the dynamics of antibacterials consumption in EMI and their main departments, in comparison with hospitals
from other worldwide countries, represents important arguments and reserves for improving quality treatment, planning, rational prescription and
utilization of antibiotics in hospitals.
Description:
Department of Medical Emergency, Nicolae Testemitsanu State University of Medicine and Pharmacy, Department of Quality of Medical Services Management, Emergency Medicine Institute, Medicines and Medical Devices Agency, Chisinau, the Republic of Moldova
