Early initiation of the DMARD treatment leads to improvement of the clinical and radiological outcome. Obtaining sustained remissions or low activity of the disease, is also more easily achieved by early applying treatment. ...

The disease activity threshold necessary to start DMARD by combined or monotherapy was established arbitrary, for patient with axial spondylo arthritis, at BASDAI ≥4. At the moment, the correlation between the activity ...

One of the major outcomes in chronic rheumatological diseases is the imparment of physical function. One of the major purposes of treatment is to improve the physical function and mantain it at an acceptable level. The ...

Significant improvement on the ACR criteria (> 50) at the end of the study was observed in most patients treated with methotrexate, leflunomide and Wobenzym. This is confirmed by a statistically and clinically significant ...

Just as in the case of other diseases, in gout the primary and/or secondary prophylaxis may be suggested as well as the treatment of the disease in its acute phase and the basic one. The fact to be mentioned is that no ...