Abstract:
Background. ‘Cognitive impairment’ and ‘frailty’ are the
most prevalent geriatric syndromes that coexist in older
adults imposing significant financial burdens on healthcare
systems. Progressive age-related cumulative changes are
reflected by increased dependency, vulnerability, disability,
and mortality. Objective of the study. To evaluate cognitive
impairment and research factors that can accelerate or delay aging related health and prognosis. Material and methods. The pathophysiology, association roles, and screening
techniques were reviewed using selected 60 PUBMED database’s 2018–2023 papers. Results. Frailty and related cognitive impairment were shown to be significantly correlated.
Numerous aggravating factors including physiological (lower hormone functions, senescence of all organ systems), genetic, environmental, physical (comorbidities, polypharmacy), and mental pathologies (psychosocial and emotional)
were identified. Conclusions. Reliable early indicators and
screening algorithms are crucial. A recent brief community
screening approach combines self-administered tools like
p-AD8 + IQCODE questionnaires for primary and DemTect
+ MoCA test for secondary evaluation. The implementation of simple preventive measures like including mobility,
strength and resistance training, proper nutrition, adequate
management of comorbidities, active participation in more
social, and cognitive activities that can delay progression is
critical. Avoiding polypharmacy and adequate treatment of
comorbidities can improve cognitive status in elderly
