Abstract:
Background. Diffuse idiopathic skeletal hyperostosis
(DISH) is a rheumatologic condition characterized by ossification of the spinal ligaments and tendons with unknown
etiopathology. DISH primarily affects the elderly. The presence of DISH may indicate underlying metabolic derangement and is associated with cardiovascular disease, obesity,
osteoarthritis, diabetes mellitus. Objective of the study.
evaluated the clinical aspects of DISH. Material and methods. Through the PubMed, NCBI, NIH databases Rheum
and Science Direct 50 publications were selected. Results.
DISH may present with no symptoms or with impaired status. Bone depositions with formation of obstructive masses
may lead to biomechanical changes of the musculoskeletal
system and/or the multiorgan implication. Clinical symptoms include a large variety of complains morning stiffness,
spinal pain, radiculopathy, myelopathy, para-, tetra paresis,
decrease lung capacity with airway obstruction, dysphagia, dysphonia, rhinolalia due to irritation of the recurrent laryngeal nerve, imprisonment syndromes may occur. Mild
impact trauma may provoke fractures. Older age, male sex,
obesity, hypertension, atherosclerosis, diabetes mellitus has
all been linked to the prevalence of DISH. The disease can
cause severe complications. Early diagnosis and prophylaxis are important. Imaging methods are the priority in visualizing extensive bone proliferation. Conclusions. Because
the disease evolves for a long time asymptomatically or with
minor symptoms, patients in the at-risk group require increased medical and personal vigilance. Imaging examinations (X-ray, computed tomography) and prophylactic treatment to control the pathological bone proliferation process
are important.
