Introducere. Boala arterială periferică afectează peste 200 de milioane de persoane la nivel global şi frecvent duce la complicaţii severe, inclusiv la ischemia cronică a membrelor inferioare (ICMI). Prevalenţa ICMI la femei este mai mică decât la bărbaţi, particularităţile clinico-evolutive fiind studiate insuficient. Scop. Evidenţierea diferenţelor clinico-paraclinice, anatomice, de tratament şi evoluţia postoperatorie asociate cu gen la pacienţii cu ICMI supuşi intervenţiilor de revascularizare. Material şi metode. A fost efectuat un studiu prospectiv care a inclus 118 pacienţi cu ICMI (90 bărbaţi şi 28 femei). Au fost înregistrate: date demografice, antropometrice, factorii de risc, comorbidităţi, simptome clinice ale ischemiei, rezultatele examinărilor paraclinice, tipul şi rezultatul precoce a intervenţiei de re-vascularizare. Rezultate. Femeile au avut o vârstă 74 (6879) ani vs 68 (62-74) ani la bărbaţi ş mai frecvent sufereau de diabet zaharat 67% vs 34%, fibrilaţia atrială 18% vs 15% şi boala renală cronică 17% vs 5%, p<0,05. Hemoglobina a fost mai mică la femei: 116 (105-128) vs 131 (119-143) g/l, iar tabagismul a fost mai rar 3,6% vs 54%, p<0,05. Pentru ICMI stadiul IIB au fost operaţi 16% bărbaţi şi doar 3,5% femei, distanţa de mers fără durerea fiind mai scurtă la femei: 20 (12-50) vs 50 (20-100) m, p<0,05. La femei mai frecvent s-au practicat intervenţii endovasculare 89% vs 61%, p<0,05. NU au fost diferenţe în rezultatul imediat al revascularizării. Concluzii. Pacientele cu ICMI reprezintă un grup particular, fiind supuse revascularizării la vârste mai înaintate, în contextul unor comorbidităţi cronice multiple şi al unor stadii mai avansate ale bolii. Sunt necesare cercetări suplimentare privind eficienţa pe termen lung a tratamentului.
Introduction. Peripheral artery disease affects over 200 million people worldwide and often leads to severe complications, including chronic limb-threatening ischemia (CLTI). The prevalence of CLTI is lower in women compared to men, and its clinical and evolutionary characteristics in women remain insufficiently studied. Objective. To highlight gender-associated differences in clinical features, anatomical patterns, treatment strategies, and postoperative outcomes in CLTI patients undergoing revascularization. Material and methods. A prospective study was conducted, including 118 patients with CLTI (90 men and 28 women). The following data were recorded: demographic and anthropometric information, risk factors, comorbidities, clinical symptoms of ischemia, results of paraclinical examinations, type of revascularization procedure, and early outcomes. Results. Women were older, median age 74 (68-79) vs 68 (62-74) years in men, and more frequently had diabetes (67% vs 34%), atrial fibrillation (18% vs 15%), and chronic kidney disease (17% vs 5%), all p<0,05. Hemoglobin levels were lower in women (116 vs 131 g/l), and smoking was significantly less frequent (3,6% vs 54%), p<0,05. For stage IIB CLTI, only 3,5% women vs 16% underwent surgery. Pain-free walking distance was shorter in women (20 vs 50 m), p<0,05. Endovascular procedures were more frequent in women (89% vs 61%), p<0,05. Endovascular procedures were frequent in women (89% vs 61%), p<0,05. Immediate revascularization outcomes showed no significant gender differences. Conclusion. Female patients represent a distinct subgroup of individuals with CLTI, undergoing revascularization at an older age, with a higher burden of chronic comorbidities and more advanced stages of ischemia. Further studies are needed to assess long-term treatment outcomes in this population.
