| dc.contributor.author | Fosa, Doina | |
| dc.contributor.author | Sipitco, Natalia | |
| dc.date.accessioned | 2025-12-06T12:50:28Z | |
| dc.date.accessioned | 2025-12-07T15:43:54Z | |
| dc.date.available | 2025-12-06T12:50:28Z | |
| dc.date.available | 2025-12-07T15:43:54Z | |
| dc.date.issued | 2025 | |
| dc.identifier.citation | Fosa, Doina; Sipitco, Natalia. ESOFAGUL BARRETT SUB MICROSCOPUL TEHNOLOGIEI - CE E NOU ÎN 2025? = BARRETT'S ESOPHAGUS UNDER THE MICROSCOPE OF TECHNOLOGY - WHAT'S NEW IN 2025?. In: Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences. 2025, vol. 12, Nr. 3/2025, anexa 2, p. 353. ISSN 2345-1467. | en_US |
| dc.identifier.issn | 2345-1467 | |
| dc.identifier.uri | https://cercetare.usmf.md/sites/default/files/2025-10/MJHS_12_2_2025_anexa2site.pdf | |
| dc.identifier.uri | https://repository.usmf.md/handle/20.500.12710/32084 | |
| dc.description | Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”, Chișinău, Republica Moldova | en_US |
| dc.description.abstract | Introducere. În ultimii ani cercetările potenţialului diag-nostico-curativ al Barrett-ului au avansat semnificativ. En-doscopia asistată de Inteligenţa Artificială (IA), biomarkerii moleculari, endoablaţiile asociate imunoterapiei au ameliorat diagnosticul precoce, stratificarea riscului/progresiei spre neoplazie. Scop. Scopul acestei cercetări este de a analiza, sintetiza şi de a aprecia impactul celor mai recente inovaţii în diagnosticul şi tratamentul esofagului Barrett, apărute în perioada 2022-2025. Material şi metode. Lucrarea a fost realizată accesând bazele de date PubMed, Scopus, Embase, Cochrane şi Google Scholar folosind sintaxe constînd din | ro_RO |
| dc.description.abstract | Introduction. In recent years, research into the diagnostic and curative potential of Barrett's has advanced significantly. Artificial Intelligence (Al)-assisted endoscopy, molecular biomarkers, endoablation associated with immunotherapy have improved early diagnosis, risk stratification/progression to neoplasia. Objective. The aim of this research is to analyze, synthesize, and assess the impact of the latest innovations in the diagnosis and treatment of Barrett's esophagus, which emerged during the period 2022-2025. Material and methods. The work was carried out by accessing the PubMed, Scopus, Embase, Cochrane and Google Scholar databases using syntaxes consisting of | en_US |
| dc.publisher | en_US | |
| dc.relation.ispartof | Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences | en_US |
| dc.subject | (“Barrett’s esophagus” | en_US |
| dc.subject | “Esophageal adenocarcinoma” | en_US |
| dc.subject | “Biomarkers” | en_US |
| dc.subject | “GERD” | en_US |
| dc.subject | “Endoluminal treatment”). The search restriction was used in English and the years of publication 2022-2025. Results. Barrett’s diagnosis has new methods and strategies | en_US |
| dc.subject | Non-invasive tests | en_US |
| dc.subject | Cytosponge -TFF3 - validated test in Barrett’s screening | en_US |
| dc.subject | a sponge capsule + TFF3 biomarker) | en_US |
| dc.subject | Molecular biomarkers (TP53 | en_US |
| dc.subject | VIM | en_US |
| dc.subject | NELL1 | en_US |
| dc.subject | CDKN2A) | en_US |
| dc.subject | mi-croRNA (miR-21 | en_US |
| dc.subject | miR-215) | en_US |
| dc.subject | Artificial Intelligence (AI systems incorporated into endoscopy visually detect dysplasia | en_US |
| dc.subject | and associated with biomarkers has a personalized prediction of the risk of neoplasia. In treatment | en_US |
| dc.subject | Radiofrequency (RFA) remains the standard for high-grade dysplasia and uncomplicated Barrett’s esophagus | en_US |
| dc.subject | endoscopic mucosectomy is used for focal lesions or suspected incipient neoplasia. Conclusion. The diagnosis of Barrett’s esophagus is becoming less invasive | en_US |
| dc.subject | based on molecular techniques and AI. The treatment is personalized | en_US |
| dc.subject | risk stratification | en_US |
| dc.subject | AI-guided ablations | en_US |
| dc.subject | alternative methods to RFA. Technical progress validates endoscopic therapy as a key method in the treatment of Barrett’s | en_US |
| dc.title | ESOFAGUL BARRETT SUB MICROSCOPUL TEHNOLOGIEI - CE E NOU ÎN 2025? | ro_RO |
| dc.title.alternative | BARRETT'S ESOPHAGUS UNDER THE MICROSCOPE OF TECHNOLOGY - WHAT'S NEW IN 2025? | en_US |
| dc.type | Article | en_US |