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ESOFAGUL BARRETT SUB MICROSCOPUL TEHNOLOGIEI - CE E NOU ÎN 2025?

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dc.contributor.author Fosa, Doina
dc.contributor.author Sipitco, Natalia
dc.date.accessioned 2025-12-06T12:50:28Z
dc.date.accessioned 2025-12-07T15:43:54Z
dc.date.available 2025-12-06T12:50:28Z
dc.date.available 2025-12-07T15:43:54Z
dc.date.issued 2025
dc.identifier.citation Fosa, Doina; Sipitco, Natalia. ESOFAGUL BARRETT SUB MICROSCOPUL TEHNOLOGIEI - CE E NOU ÎN 2025? = BARRETT'S ESOPHAGUS UNDER THE MICROSCOPE OF TECHNOLOGY - WHAT'S NEW IN 2025?. In: Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences. 2025, vol. 12, Nr. 3/2025, anexa 2, p. 353. ISSN 2345-1467. en_US
dc.identifier.issn 2345-1467
dc.identifier.uri https://cercetare.usmf.md/sites/default/files/2025-10/MJHS_12_2_2025_anexa2site.pdf
dc.identifier.uri https://repository.usmf.md/handle/20.500.12710/32084
dc.description Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”, Chișinău, Republica Moldova en_US
dc.description.abstract Introducere. În ultimii ani cercetările potenţialului diag-nostico-curativ al Barrett-ului au avansat semnificativ. En-doscopia asistată de Inteligenţa Artificială (IA), biomarkerii moleculari, endoablaţiile asociate imunoterapiei au ameliorat diagnosticul precoce, stratificarea riscului/progresiei spre neoplazie. Scop. Scopul acestei cercetări este de a analiza, sintetiza şi de a aprecia impactul celor mai recente inovaţii în diagnosticul şi tratamentul esofagului Barrett, apărute în perioada 2022-2025. Material şi metode. Lucrarea a fost realizată accesând bazele de date PubMed, Scopus, Embase, Cochrane şi Google Scholar folosind sintaxe constînd din ro_RO
dc.description.abstract Introduction. In recent years, research into the diagnostic and curative potential of Barrett's has advanced significantly. Artificial Intelligence (Al)-assisted endoscopy, molecular biomarkers, endoablation associated with immunotherapy have improved early diagnosis, risk stratification/progression to neoplasia. Objective. The aim of this research is to analyze, synthesize, and assess the impact of the latest innovations in the diagnosis and treatment of Barrett's esophagus, which emerged during the period 2022-2025. Material and methods. The work was carried out by accessing the PubMed, Scopus, Embase, Cochrane and Google Scholar databases using syntaxes consisting of en_US
dc.publisher en_US
dc.relation.ispartof Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences en_US
dc.subject (“Barrett’s esophagus” en_US
dc.subject “Esophageal adenocarcinoma” en_US
dc.subject “Biomarkers” en_US
dc.subject “GERD” en_US
dc.subject “Endoluminal treatment”). The search restriction was used in English and the years of publication 2022-2025. Results. Barrett’s diagnosis has new methods and strategies en_US
dc.subject Non-invasive tests en_US
dc.subject Cytosponge -TFF3 - validated test in Barrett’s screening en_US
dc.subject a sponge capsule + TFF3 biomarker) en_US
dc.subject Molecular biomarkers (TP53 en_US
dc.subject VIM en_US
dc.subject NELL1 en_US
dc.subject CDKN2A) en_US
dc.subject mi-croRNA (miR-21 en_US
dc.subject miR-215) en_US
dc.subject Artificial Intelligence (AI systems incorporated into endoscopy visually detect dysplasia en_US
dc.subject and associated with biomarkers has a personalized prediction of the risk of neoplasia. In treatment en_US
dc.subject Radiofrequency (RFA) remains the standard for high-grade dysplasia and uncomplicated Barrett’s esophagus en_US
dc.subject endoscopic mucosectomy is used for focal lesions or suspected incipient neoplasia. Conclusion. The diagnosis of Barrett’s esophagus is becoming less invasive en_US
dc.subject based on molecular techniques and AI. The treatment is personalized en_US
dc.subject risk stratification en_US
dc.subject AI-guided ablations en_US
dc.subject alternative methods to RFA. Technical progress validates endoscopic therapy as a key method in the treatment of Barrett’s en_US
dc.title ESOFAGUL BARRETT SUB MICROSCOPUL TEHNOLOGIEI - CE E NOU ÎN 2025? ro_RO
dc.title.alternative BARRETT'S ESOPHAGUS UNDER THE MICROSCOPE OF TECHNOLOGY - WHAT'S NEW IN 2025? en_US
dc.type Article en_US


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