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Aplicarea criteriilor neuropsihiatrice ACR, 1999 în lupusul eritematos sistemic

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dc.contributor.author Soroceanu, Ala
dc.contributor.author Mazur-Nicorici, Lucia
dc.contributor.author Lisnic, Vitalie
dc.contributor.author Soroceanu, Sergiu
dc.contributor.author Samohvalov, Elena
dc.contributor.author Mazur, Minodora
dc.date.accessioned 2019-06-25T12:51:28Z
dc.date.available 2019-06-25T12:51:28Z
dc.date.issued 2010
dc.identifier.citation SOROCEANU, Ala, MAZUR-NICORICI, Lucia et al. Aplicarea criteriilor neuropsihiatrice ACR, 1999 în lupusul eritematos sistemic. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 3: Probleme actuale în medicina internă, pp. 83-86. en_US
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/4124
dc.description Catedra Medicină Internă nr.3, Catedra Neurologie USMF “Nicolae Testemiţanu” en_US
dc.description.abstract Nervous system involvement in systemic lupus erythematosus (SLE) is recognized for over 100 years. American College of Rheumatology criteria (ACR) 1997 classification of SLE, include neuropsychiatric (NP) manifestations as seizures and psychosis. ACR lupus research and commission convened in 1999 an ad - hoc multidisciplinary committee to develop standard nomenclature for neuropsychiatric systemic lupus erythematosus (NPSLE). Purpose of the our study was to evaluate neuropsychiatric syndromes in patients with SLE by the NPSLE criteria. We examined 60 consecutive patients with SLE who met the ACR criteria, forming the study group. Special investigations focused assessment of disease activity, estimated implementation of Hamilton depression scale, Hamilton rating scale for anxiety, and cognitive dysfunction assessment by Mini Mental Status Scale. During the study was identified 21 (35. 0%) cases of depression, 7 (11. 7%) of anxiety and 17 (28. 3%) patients of cognitive dysfunction. Application of neuropsychological tests showed early detection of nervous system involvement and adequate treatment of systemic lupus erythematosus Implicarea sistemului nervos în lupusul eritematos sistemic (LES) este recunoscută de peste 100 de ani. Criteriile Colegiului American de Reumatologie (ACR) 1997 pentru clasificarea LES, includ manifestări neuropsihiatrice (NP) convulsiile şi psihoza. ACR şi comisia pentru cercetare a lupusului a convocat în 1999 un comitet ad-hoc multidisciplinar, pentru a dezvolta nomenclatura standard pentru lupusul eritematos sistemic neuropsihiatric. Obiectivul lucrării: evaluarea sindroamelor neuropsihiatrice la pacienţii cu lupus eritematos sistemic prin aplicarea criteriilor neuropsihiatrice ale lupusului eritematos sistemic (NPLES).În studiu am inclus 60 pacienţi consecutivi cu LES care au respectat criteriile ACR, 1997, formând lotul de studiu. Investigaţiile speciale au vizat aprecierea activităţii bolii, aplicarea scalei Hamilton de estimare a depresiei şi de evaluare a anxietăţii, precum şi aprecierea disfuncţiilor cognitive prin scala Mini Mental Status. Pe parcursul studiului au fost identificate 21 (35.0 %) cazuri de depresie, 7(11.7%) cazuri de anxietate şi 17(28.3%) cazuri de disfuncţii cognitive. Aplicarea testelor neuropsihologice a demonstrat depistarea precoce a implicării sistemului nervos şi tratamentul adecvat al lupusului eritematos sistemic en_US
dc.language.iso ro en_US
dc.publisher CEP "Medicina" en_US
dc.subject.mesh Lupus Erythematosus, Systemic - complications en_US
dc.subject.mesh Lupus Erythematosus, Systemic - pathology en_US
dc.subject.mesh Nervous System Diseases - pathology en_US
dc.subject.mesh Neurologic Manifestations en_US
dc.subject.mesh Neurocognitive Disorders-immunology en_US
dc.title Aplicarea criteriilor neuropsihiatrice ACR, 1999 în lupusul eritematos sistemic en_US
dc.type Article en_US


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