Utilizarea procalcitoninei test rapid semi cantitativ ca marker în boala inflamatorie pelvină acută

Abstract

Acute pelvic inflammatory disease is defined as an ascending infection of the upper genital tract leading to infection of the endometrium, fallopian tubes, ovaries and peritoneum. Acute PID is an ill understood, inaccurately diagnosed inadequately treated condition. This often leads to potentially serious squeal such as disseminated infection, infertility, ectopic pregnancy, increased risk of reinfection and chronic pelvic pain. Diagnostic difficulties of acute PID are compounded by the wide variety of clinical presentation. Early diagnosis and appropriate therapy of PID is a daily challenge for doctors. Other diagnostic modalities beside clinical signs and symptoms include: C reactive protein and erythrocyte sedimentation rate, both these tests have been extensively studied and seem to do equally well in term of sensitivity and specificity. Among the newest markers for evaluation of severity , procalcitonin has the highest diagnostic accuracy. Procalcitonin levels rise rapidly after infectious insult with systemic consequences. Daily changes of plasma PCT levels can give an indication of the course of the disease and the prognosis of the septics complications. The priorities in combating pelvic inflammatory disease is to identify the high risk population, educated them find cost effective diagnostic tests. Research needs to address speedy and early diagnosis on an outpatient basis and to identify women who are greatest risk of developing the squeal of pelvic inflammatory disease. Keywords: Procalcitonin (PCT), Pelvic Inflammatory Disease (PID/BIP), PCR

Boala inflamatorie pelvină reprezintă cea mai frecventă cauza de adresare a pacinetelor în cabinetele ginecologice, la medicii de familie şi în serviciile de ginecologie.Boala Inflamatorie Pelvină este o infecţie frecventă unde fiziopatologia rămine puţin cunoscută, întâlnită în 44-65% la femei pâna 25 ani din care 1/3 înainte de 20 ani, la nulipare între 50-75% din cazuri, cu pariteneri multipli, ce poate aparea în perioada de menstra care se explica prin lipsa glerei cervicale în prezenţa sângelui - un mediu excelent de cultură pentru bacterii.