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Antibioticorezistenta/sensibilitatea in infectiile septico-purulente nosocomiale de profil ortopedo-traumatologic

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dc.contributor.author Prisacari, Viorel
dc.contributor.author Spataru, Diana
dc.date.accessioned 2019-06-26T05:12:58Z
dc.date.available 2019-06-26T05:12:58Z
dc.date.issued 2013
dc.identifier.citation Prisacari, V.. Antibioticorezistenta/sensibilitatea in infectiile septico-purulente nosocomiale de profil ortopedo-traumatologic / V. Prisacari, D. Spataru // Curierul medical. - 2013. - Vol. 56, Nr. 6. - P. 99-106. - Bibliogr. : p. 106. en_US
dc.identifier.issn ISSN 1857-0666
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/5496
dc.description Department of Epidemiology, Nicolae Testemitsanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova en_US
dc.description.abstract The study describes the antibiotic resistance of causative agents of purulent septic infections in patients of hospitals of ortopedic and traumatological profile. It includes 1269 patients from whom 2013 strains of microorganisms have been isolated. As a result of the analysis of antibiograms, a high resistance of strains to antibiotics have been detected (50.16%), including gram-negative microorganisms – 57.72% and gram-positive ones – 46.09%. A high level of antibiotic resistance has been identified in such microorganisms as Acinetobacter (85.72%), E. cloacae (71.43%), C. diversus (64.78%), K. pneumoniae (64.54%) and P. aeruginosa (62.78%). Depending on the antibiotic group, a higher resistance of these strains to penicillins (63.95%), cephalosporins (66.15%) and, especially, to the third generation of cephalosporins (69.35%) has been detected. Purulent septic pathology in hospitals of ortopedic and traumatological profile is of poly-etiologic nature and characterized by a high resistance of the pathogen agents to antibiotics. At the same time, the sensitivity/resistance of the causative agents is very diverse, the values of which, depending on the group of antibiotics, are from 29.0 to 97.0% – sensitive, and vice versa, from 26.0 up to 98.0% – resistant. A high resistance to antibiotics has been established in gram-negative microorganisms (57.72%), including Acinetobacter (85.72%), E. cloacae (free 71.43%), C. diversus (64.78%), K. pneumoniae (64.54%), P. aeruginosa (62.78%), in particular, to penicillins and cephalosporins, the antibiotics widely used in medical practice. The results of the study demonstrate the need for the development and implementation of the programme on surveillance and control of microbial antibiotic resistance suitable to a medical hospital. en_US
dc.language.iso ro en_US
dc.publisher Curierul medical en_US
dc.subject.mesh Drug Resistance, Bacterial en_US
dc.subject.mesh Sepsis - drug therapy en_US
dc.subject.mesh Gram-Positive Bacteria - drug effects en_US
dc.subject.mesh Gram-Negative Bacteria - drug effects en_US
dc.title Antibioticorezistenta/sensibilitatea in infectiile septico-purulente nosocomiale de profil ortopedo-traumatologic en_US
dc.title.alternative Antibiotic resistance/sensitivity of the purulent septic nosocomial infections in hospitals of orthopedic and traumatological profile en_US
dc.type Article en_US


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